High-level Accurate Model of High-resolution Pipelined ADC's

Author(s):  
C. Azzolini
2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Sergey V. Ulianov ◽  
Vlada V. Zakharova ◽  
Aleksandra A. Galitsyna ◽  
Pavel I. Kos ◽  
Kirill E. Polovnikov ◽  
...  

AbstractMammalian and Drosophila genomes are partitioned into topologically associating domains (TADs). Although this partitioning has been reported to be functionally relevant, it is unclear whether TADs represent true physical units located at the same genomic positions in each cell nucleus or emerge as an average of numerous alternative chromatin folding patterns in a cell population. Here, we use a single-nucleus Hi-C technique to construct high-resolution Hi-C maps in individual Drosophila genomes. These maps demonstrate chromatin compartmentalization at the megabase scale and partitioning of the genome into non-hierarchical TADs at the scale of 100 kb, which closely resembles the TAD profile in the bulk in situ Hi-C data. Over 40% of TAD boundaries are conserved between individual nuclei and possess a high level of active epigenetic marks. Polymer simulations demonstrate that chromatin folding is best described by the random walk model within TADs and is most suitably approximated by a crumpled globule build of Gaussian blobs at longer distances. We observe prominent cell-to-cell variability in the long-range contacts between either active genome loci or between Polycomb-bound regions, suggesting an important contribution of stochastic processes to the formation of the Drosophila 3D genome.


2010 ◽  
Vol 14 (2) ◽  
pp. 393-405 ◽  
Author(s):  
S. Trevisani ◽  
M. Cavalli ◽  
L. Marchi

Abstract. High-resolution topographic data expand the potential of quantitative analysis of the earth surface, improving the interpretation of geomorphic processes. In particular, the morphologies of the channel beds of mountain streams, which are characterised by strong spatial variability, can be analysed much more effectively with this type of data. In this study, we analysed the aerial LiDAR topographic data of a headwater stream, the Rio Cordon (watershed area: 5 km2), located in the Dolomites (north-eastern Italy). The morphology of the channel bed of Rio Cordon is characterised by alternating step pools, cascades, and rapids with steps. We analysed the streambed morphology by means of ad hoc developed morphometric indices, capable of highlighting morphological features at a high level of spatial resolution. To perform the analysis and the data interpolation, we carried out a channel-oriented coordinate transformation. In the new coordinate system, the calculation of morphometric indices in directions along and transverse to the flow direction is straightforward. Three geomorphometric indices were developed and applied as follows: a slope index computed on the whole width of the channel bed, directional variograms computed along the flow direction and perpendicular to it, and local anomalies, calculated as the difference between directional variograms at different spatial scales. Directional variograms in the flow direction and local anomalies have proven to be effective at recognising morphologic units, such as steps, pools and clusters of large boulders. At the spatial scale of channel reaches, these indices have demonstrated a satisfactory capability to outline patterns associated with boulder cascades and rapids with steps, whereas they did not clearly differentiate between morphologies with less marked morphological differences, such as step pools and cascades.


2018 ◽  
Vol 10 (11) ◽  
pp. 1768 ◽  
Author(s):  
Hui Yang ◽  
Penghai Wu ◽  
Xuedong Yao ◽  
Yanlan Wu ◽  
Biao Wang ◽  
...  

Building extraction from very high resolution (VHR) imagery plays an important role in urban planning, disaster management, navigation, updating geographic databases, and several other geospatial applications. Compared with the traditional building extraction approaches, deep learning networks have recently shown outstanding performance in this task by using both high-level and low-level feature maps. However, it is difficult to utilize different level features rationally with the present deep learning networks. To tackle this problem, a novel network based on DenseNets and the attention mechanism was proposed, called the dense-attention network (DAN). The DAN contains an encoder part and a decoder part which are separately composed of lightweight DenseNets and a spatial attention fusion module. The proposed encoder–decoder architecture can strengthen feature propagation and effectively bring higher-level feature information to suppress the low-level feature and noises. Experimental results based on public international society for photogrammetry and remote sensing (ISPRS) datasets with only red–green–blue (RGB) images demonstrated that the proposed DAN achieved a higher score (96.16% overall accuracy (OA), 92.56% F1 score, 90.56% mean intersection over union (MIOU), less training and response time and higher-quality value) when compared with other deep learning methods.


Author(s):  
Michael Radermacher ◽  
Teresa Ruiz

Biological samples are radiation-sensitive and require imaging under low-dose conditions to minimize damage. As a result, images contain a high level of noise and exhibit signal-to-noise ratios that are typically significantly smaller than 1. Averaging techniques, either implicit or explicit, are used to overcome the limitations imposed by the high level of noise. Averaging of 2D images showing the same molecule in the same orientation results in highly significant projections. A high-resolution structure can be obtained by combining the information from many single-particle images to determine a 3D structure. Similarly, averaging of multiple copies of macromolecular assembly subvolumes extracted from tomographic reconstructions can lead to a virtually noise-free high-resolution structure. Cross-correlation methods are often used in the alignment and classification steps of averaging processes for both 2D images and 3D volumes. However, the high noise level can bias alignment and certain classification results. While other approaches may be implicitly affected, sensitivity to noise is most apparent in multireference alignments, 3D reference-based projection alignments and projection-based volume alignments. Here, the influence of the image signal-to-noise ratio on the value of the cross-correlation coefficient is analyzed and a method for compensating for this effect is provided.


Author(s):  
L. Ruiz Huerta ◽  
A. Caballero-Ruiz ◽  
E. Marin-Aguilar ◽  
G. Velasco-Herrera ◽  
T. Baidyk ◽  
...  

This paper describes the experience of the Laboratory of Micromechanics and Mechatronics in the production of low cost micromechanics. A case of study is discussed and explained. The importance of applying simple mechanisms and high level control systems is presented. The basic elements and components needed to develop a high resolution micromachine tool are presented. This case of study is a MicroMachine Tool of 800nm of resolution in its three translational axes. Every single axis is able to move along 20mm. The configuration of the axes is not conventional, thanks to the use of parallel elements that results in semi circular movements.


2018 ◽  
Vol 18 (6) ◽  
pp. 1567-1582 ◽  
Author(s):  
Denis Feurer ◽  
Olivier Planchon ◽  
Mohamed Amine El Maaoui ◽  
Abir Ben Slimane ◽  
Mohamed Rached Boussema ◽  
...  

Abstract. Monitoring agricultural areas threatened by soil erosion often requires decimetre topographic information over areas of several square kilometres. Airborne lidar and remotely piloted aircraft system (RPAS) imagery have the ability to provide repeated decimetre-resolution and -accuracy digital elevation models (DEMs) covering these extents, which is unrealistic with ground surveys. However, various factors hamper the dissemination of these technologies in a wide range of situations, including local regulations for RPAS and the cost for airborne laser systems and medium-format RPAS imagery. The goal of this study is to investigate the ability of low-tech kite aerial photography to obtain DEMs with decimetre resolution and accuracy that permit 3-D descriptions of active gullying in cultivated areas of several square kilometres. To this end, we developed and assessed a two-step workflow. First, we used both heuristic experimental approaches in field and numerical simulations to determine the conditions that make a photogrammetric flight possible and effective over several square kilometres with a kite and a consumer-grade camera. Second, we mapped and characterised the entire gully system of a test catchment in 3-D. We showed numerically and experimentally that using a thin and light line for the kite is key for a complete 3-D coverage over several square kilometres. We thus obtained a decimetre-resolution DEM covering 3.18 km2 with a mean error and standard deviation of the error of +7 and 22 cm respectively, hence achieving decimetre accuracy. With this data set, we showed that high-resolution topographic data permit both the detection and characterisation of an entire gully system with a high level of detail and an overall accuracy of 74 % compared to an independent field survey. Kite aerial photography with simple but appropriate equipment is hence an alternative tool that has been proven to be valuable for surveying gullies with sub-metric details in a square-kilometre-scale catchment. This case study suggests that access to high-resolution topographic data on these scales can be given to the community, which may help facilitate a better understanding of gullying processes within a broader spectrum of conditions.


2018 ◽  
Author(s):  
Vladimir V. Kalmykov ◽  
Rashit A. Ibrayev ◽  
Maxim N. Kaurkin ◽  
Konstantin V. Ushakov

Abstract. We present new version of the Compact Modeling Framework (CMF3.0) developed for providing the software environment for stand-alone and coupled models of the Global geophysical fluids. The CMF3.0 designed for implementation high and ultra-high resolution models at massive-parallel supercomputers. The key features of the previous CMF version (2.0) are mentioned for reflecting progress in our researches. In the CMF3.0 pure MPI approach with high-level abstract driver, optimized coupler interpolation and I/O algorithms is replaced with PGAS paradigm communications scheme, while central hub architecture evolves to the set of simultaneously working services. Performance tests for both versions are carried out. As addition a parallel realisation of the EnOI (Ensemble Optimal Interpolation) data assimilation method as program service of CMF3.0 is presented.


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