Lonestar: An Energy-Aware Disk Based Long-Term Archival Storage System

Author(s):  
Matthias Grawinkel ◽  
Markus Pargmann ◽  
Hubert Domer ◽  
Andre Brinkmann
2009 ◽  
Vol 5 (2) ◽  
pp. 1-35 ◽  
Author(s):  
Mark W. Storer ◽  
Kevin M. Greenan ◽  
Ethan L. Miller ◽  
Kaladhar Voruganti

2016 ◽  
Vol 51 (4) ◽  
pp. 637-649 ◽  
Author(s):  
James Bornholt ◽  
Randolph Lopez ◽  
Douglas M. Carmean ◽  
Luis Ceze ◽  
Georg Seelig ◽  
...  

Blood ◽  
2019 ◽  
Vol 134 (Supplement_1) ◽  
pp. 4995-4995
Author(s):  
Jose A Cancelas ◽  
F. Bernadette West ◽  
Matthew Karaffin ◽  
Tatsuro Yoshida ◽  
Neeta Rugg ◽  
...  

Oxidative damage, dysmetabolism and decreased levels of 2, 3-diphosphoglycerate (2,3-DPG) affect red blood cell (RBC) survival and the affinity of Hemoglobin for oxygen are relevant hallmarks of RBC storage lesion, especially in specific clinical contexts. We hypothesized that oxygen and carbon dioxide reduction followed by hypoxic/hypocapnic storage would result in amelioration of RBC lesion assessed at the end of their shelf-life and at the shelf-life mode (21 days).To determine the relevance of hypoxic/hypocapnic storage in humans, a pivotal, prospective, randomized, two‐arm, crossover, three‐center trial was conducted to evaluate [Hemanext®] hypoxic/hypocapnic processing system and was used to assess whether this process and storage method met standard FDA acceptability criteria for long-term RBC storage. The Test arm consisted of whole blood (WB)‐derived, leukoreduced RBC in AS-3 additive processed at room temperature with the Hemanext system for 3 hours to achieve hypoxic/hypocapnic state within 12 hours of phlebotomy which was maintained hypoxic during storage for up to 43 days at 1‐6°C (Test).Unprocessed units (Control) were stored within 8 hours under conventional storage conditions. Subjects (N=100) donated CP2D WB (500 ± 50 mL) and a minimum of 93 pairs of RBC units per arm were analyzed for in vitroquality parameters. For in vivo analysis at end of storage, RBCs from 19 test subjects and 21 control subjects (14 paired) from two sites were radiolabeled with 51‐Cr/99‐Tc(m), autologously transfused, and analyzed for 24-hour recovery. Differences between the Test and Control groups were analyzed using the paired t-test (Wilcoxon test where necessary). Paired analyses of 24-hour in vivorecoveries on day 43 was 89.3±4.5% and 84.8±6.2% for the test and control, respectively; p<0.01). Significantly higher levels of 2,3-DPG and adenosine 5'-triphosphate (ATP) were maintained for the Test group by days 21 and 42/43 of storage (Table 1). Percentage of hemolysis was similar in both groups. In summary, these data demonstrate that RBCs preserved in a user-friendly, self-contained hypoxic storage system are superior than the conventionally stored RBCs and may provide more viable RBCs for transfusion at 6 weeks of storage. Disclaimer: The51‐Cr/99‐Tc(m)labeling at one of the three sites occurred without prior RDRC approval and did not meet GMP standards. Disclosures Cancelas: Fresenius-Kabi: Research Funding; Cerus Co.: Research Funding; TerumoBCT: Consultancy, Research Funding; Hemanext: Consultancy, Research Funding; Macopharma Inc: Research Funding; Cytosorbents: Research Funding; Cellphire: Research Funding; Velico: Consultancy, Research Funding. Yoshida:New Health Sciences Inc.: Employment, Equity Ownership. Dioguardi:Hemanext: Employment. Iselin:Hemanext: Employment. Dunham:Hemanext: Employment.


2021 ◽  
Author(s):  
Min Li ◽  
Junbiao Dai ◽  
Qingshan Jiang ◽  
Yang Wang

Abstract Current research on DNA storage usually focuses on the improvement of storage density with reduced gene synthesis cost by developing effective encoding and decoding schemes while lacking the consideration on the uncertainty in ultra long-term data storage and retention. Consequently, the current DNA storage systems are often not self-containment, implying that they have to resort to external tools for the restoration of the stored gene data. This may result in high risks in data loss since the required tools might not be available due to the high uncertainty in far future. To address this issue, we propose in this paper a self-contained DNA storage system that can make self-explanatory to its stored data without relying on any external tools. To this end, we design a specific DNA file format whereby a separate storage scheme is developed to reduce the data redundancy while an effective indexing is designed for random read operations to the stored data file. We verified through experimental data that the proposed self-contained and self-explanatory method can not only get rid of the reliance on external tools for data restoration but also minimize the data redundancy brought about when the amount of data to be stored reaches a certain scale.


Author(s):  
Albert Alvarez-Carulla ◽  
Yaiza Montes-Cebrian ◽  
Manel Puig-Vidal ◽  
Jaime Lopez-Sanchez ◽  
Jordi Colomer-Farrarons ◽  
...  
Keyword(s):  

Energies ◽  
2020 ◽  
Vol 13 (4) ◽  
pp. 979 ◽  
Author(s):  
Caner Çuhac ◽  
Anne Mäkiranta ◽  
Petri Välisuo ◽  
Erkki Hiltunen ◽  
Mohammed Elmusrati

Solar heat, already captured by vast asphalt fields in urban areas, is potentially a huge energy resource. The vertical soil temperature profile, i.e., low enthalpy geothermal energy, reveals how efficiently the irradiation is absorbed or radiated back to the atmosphere. Measured solar irradiation, heat flux on the asphalt surface and temperature distribution over a range of depths describe the thermal energy from an asphalt surface down to 10 m depth. In this study, those variables were studied by long-term measurements in an open-air platform in Finland. To compensate the nighttime heat loss, the accumulated heat on the surface should be harvested during the sunny daytime periods. A cumulative heat flux over one year from asphalt to the ground was 70% of the cumulative solar irradiance measured during the same period. However, due to the nighttime heat losses, the net heat flux during 5 day period was only 18% of the irradiance in spring, and was negative during autumn, when the soil was cooling. These preliminary results indicate that certain adaptive heat transfer and storage mechanisms are needed to minimize the loss and turn the asphalt layer into an efficient solar heat collector connected with a seasonal storage system.


Author(s):  
Shinichi Kaita ◽  
Toshikazu Shibasaki ◽  
Takayasu Tahara

Considering long term stable supply of oil fuel, the world largest long-term storage system of crude oil has been installed in Japan. In order to ensure safety of large size above ground storage tanks, global assessment system for structural integrity of tank considering risk level and shut down inspection interval has been developed on Risk Based Inspection, RBI and Fitness-For-Service, FFS for storage tanks of crude oil for national security reserve.


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