Tumor breast phantom vs breast phantom Microwave ablation: Thermal experimentation and electric property measurements

Author(s):  
R. Ortega-Palacios ◽  
L. Leija ◽  
A. Vera
2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Kristian Segura Félix ◽  
Geshel D. Guerrero López ◽  
Mario F. J. Cepeda Rubio ◽  
José I. Hernández Jacquez ◽  
Francisco G. Flores García ◽  
...  

Introduction. Cancer is the second leading cause of death worldwide. Breast cancer is the second most common cause of cancer-related mortality, accounting for 11.6% of the total number of deaths. The main treatments for this disease are surgical removal of the tumor, radiotherapy, and chemotherapy. Recently, different minimally invasive technologies have been applied (e.g., emission of electromagnetic waves, thermal and chemical means) to overcome the important side effects of these treatment modalities. The objective of this study was to develop and evaluate a predictive computational model of microwave ablation. Materials and Methods. The predictive computational model of microwave ablation was constructed by means of a dual-slot coaxial antenna. The model was compared with an experiment performed using a breast phantom, which emulates the dielectric properties of breast tissue with segmental microcalcifications. The standing wave ratio (SWR) was obtained for both methods to make a comparison and determine the feasibility of applying electromagnetic ablation to premalignant lesions in breasts. Specifically, for the analysis of segmental microcalcifications, a breast phantom with segmental microcalcifications was developed and two computational models were performed under the same conditions (except for blood perfusion, which was excluded in one of the models). Results. The SWR was obtained by triplicate experiments in the phantom, and the measurements had a difference of 0.191 between the minimum and maximum SWR values, implying a change of power reflection of 0.8%. The average of the three measurements was compared with the simulation that did not consider blood perfusion. The comparison yielded a change of 0.104, representing a 0.2% change in power reflection. Discussion. Both experimentation in phantom and simulations demonstrated that ablation therapy can be performed using this antenna. However, an additional optimization procedure is warranted to increase the efficiency of the antenna.


2020 ◽  
Vol 21 (3) ◽  
pp. 1-13
Author(s):  
José Irving Hernández Jacquez ◽  
Mario Francisco Jesús Cepeda Rubio ◽  
Geshel David Guerrero López ◽  
Arturo Vera Hernández ◽  
Lorenzo Leija Salas ◽  
...  

Breast cancer is one of the most common types of cancer in females around the world, surgery is the preferred treatment for this disease in early stages, however there are some emergent treatment options with less clinical and cosmetically repercussions, being one of these the microwave ablation. Microwave ablation is a minimally invasive technique used to treat tumors in different organs of the human body, mainly in liver, lung and kidney. It consist on the destruction of the tumor by rising the temperature of the cells until necrosis is achieve. In breast tumors, this technique has been rarely used in human patients. Depending on the type of tissue, an applicator must be made to be coupled to ensure that energy used is not reflected, so the standing wave ratio is closest to 1. In order to determine an appropriate design for the applicators that could be used for the treatment of breast cancer, an in-silico study of microwave ablation of breast cancer was made to show the difference between micro-coaxial applicators constructed with two different types of coaxial cable (UT-47 and UT-85) utilizing the same design in three possible scenarios breast tissue, tumor tissue and tumor surrounded by breast tissue. The simulation was realized using COMSOL Multiphysics commercial software, due to its capabilities to simulate the electromagnetics and thermals effects. A slot type applicator was selected because of its ease of manufacture and the available literature on it. The results shows a better coupling for the applicator constructed with the UT-47 cable, especially in the tumor phantom surrounded by breast phantom test.


Electronics ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 535 ◽  
Author(s):  
Rocío Ortega-Palacios ◽  
Citlalli Jessica Trujillo-Romero ◽  
Mario Francisco Jesús Cepeda-Rubio ◽  
Lorenzo Leija ◽  
Arturo Vera Hernández

It is worldwide known that the most common type of cancer among women is breast cancer. Traditional procedures involve surgery, chemotherapy and radiation therapy; however, these treatments are invasive and have serious side effects. For this reason, minimally invasive thermal treatments like microwave ablation are being considered. In this study, thermal behavior of three types of slot-coaxial antennas for breast cancer microwave ablation is presented. By using finite element method (FEM), all antennas were modeled to estimate the heat transfer in breast tumor tissue surrounded by healthy breast tissue. Experimentation was carried out by using the antennas inserted inside sphere-shaped-tumor phantoms with two different diameters, 1.0 and 1.5 cm. A microwave radiation system was used to apply microwave energy to each designed antenna, which were located into the phantom. A non-interfering thermometry system was used to measure the temperature increase during the experimentation. Temperature increases, recorded by the thermal sensors placed inside the tumor phantom surrounded by healthy breast phantom, were used to validate the FEM models. The results conclude that, in all the cases, after 240 s, the three types of coaxial slot antenna reached the temperature needed produce hyperthermia of the tumor volume considered in this paper.


Author(s):  
N Nour-Eldin Mohammed ◽  
N Nguib ◽  
S Zangos ◽  
T Lehnert ◽  
T Gruber-Rouh ◽  
...  

2005 ◽  
Vol 8 (4) ◽  
pp. E269-E274 ◽  
Author(s):  
Sydney L. Gaynor ◽  
Gregory D. Byrd ◽  
Michael D. Diodato ◽  
Yosuke Ishii ◽  
Anson M. Lee ◽  
...  

2016 ◽  
Vol 136 (2) ◽  
pp. 93-98 ◽  
Author(s):  
Paolo Mancinelli ◽  
Valentina Santangelo ◽  
Davide Fabiani ◽  
Andrea Saccani ◽  
Maurizio Toselli ◽  
...  

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