A New Sex Chromosome Marker, Similar to DNA Polymerase Type B, in the Platyfish Xiphophorus Maculatus

2008 ◽  
Author(s):  
Qingchun Zhou ◽  
Alexander Froschauer ◽  
Christina Schultheis ◽  
Ingo Braasch ◽  
Manfred Scahartl ◽  
...  
Keyword(s):  
Dna Polymerase ◽  
Sex Chromosome ◽  
Type B ◽  
Chromosome Marker ◽  
Xiphophorus Maculatus

Type B Hepatitis: The Infectivity of Blood Positive for E Antigen and DNA Polymerase after Accidental Needlestick Exposure

1976 ◽  
Vol 295 (17) ◽  
pp. 909-913 ◽  
Author(s):  
Harvey J. Alter ◽  
Leonard B. Seeff ◽  
Paul M. Kaplan ◽  
Vincent J. McAuliffe ◽  
Elizabeth C. Wright ◽  
...  
Keyword(s):  
Dna Polymerase ◽  
Type B

scholarly journals Homology of melanoma-inducing loci in the genus Xiphophorus.

Genetics ◽  
1990 ◽  
Vol 126 (4) ◽  
pp. 1083-1091 ◽  
Author(s):  
M Schartl
Keyword(s):  
Receptor Tyrosine Kinase ◽  
Sex Chromosome ◽  
Duplication Event ◽  
Molecular Probes ◽  
Fish Populations ◽  
Gene Duplication Event ◽  
Oncogenic Potential ◽  
Mendelian Genetics ◽  
Xiphophorus Maculatus ◽  
Different Populations

Abstract Several species of the genus Xiphophorus are polymorphic for specific pigment patterns. Some of these give rise to malignant melanoma following the appropriate crossings. For one of these pattern loci from the playfish Xiphophorus maculatus the melanoma-inducing gene has been cloned and found to encode a novel receptor tyrosine kinase, designated Xmrk. Using molecular probes from this gene in Southern blot analyses on single fish DNA preparations from 600 specimens of different populations of various species of the genus Xiphophorus and their hybrids, either with or without melanoma-predisposing pattern, it was shown that all individuals contain the Xmrk gene as a proto-oncogene. It is located on the sex chromosome. All fish that carry a melanoma-predisposing locus which has been identified by Mendelian genetics contain an additional copy of Xmrk, closely linked to a specific melanophore pattern locus on the sex chromosome. The melanoma-inducing loci of the different species and populations are homologous. The additional copy of Xmrk obviously arose by a gene-duplication event, thereby acquiring the oncogenic potential. The homology of the melanoma-inducing loci points to a similar mechanism of tumor suppression in all feral fish populations of the different species of the genus Xiphophorus.

scholarly journals MAINTENANCE OF THE THREE SEX CHROMOSOME POLYMORPHISM IN THE PLATYFISH, XIPHOPHORUS MACULATUS

Evolution ◽  
1980 ◽  
Vol 34 (4) ◽  
pp. 663-672 ◽  
Author(s):  
Steven Hecht Orzack ◽  
Joel J. Sohn ◽  
Klaus D. Kallman ◽  
Simon A. Levin ◽  
Ross Johnston
Keyword(s):  
Sex Chromosome ◽  
Chromosome Polymorphism ◽  
Xiphophorus Maculatus

Maintenance of the Three Sex Chromosome Polymorphism in the Platyfish, Xiphophorus maculatus

Evolution ◽  
1980 ◽  
Vol 34 (4) ◽  
pp. 663 ◽  
Author(s):  
Steven Hecht Orzack ◽  
Joel J. Sohn ◽  
Klaus D. Kallman ◽  
Simon A. Levin ◽  
Ross Johnston
Keyword(s):  
Sex Chromosome ◽  
Chromosome Polymorphism ◽  
Xiphophorus Maculatus

Gene structure, purification and characterization of DNA polymerase β from Xiphophorus maculatus

2004 ◽  
Vol 138 (3) ◽  
pp. 311-324 ◽  
Author(s):  
Leon P. Oehlers ◽  
Sheila J. Heater ◽  
J. Douglas Rains ◽  
Melissa C. Wells ◽  
Wendi M. David ◽  
...  
Keyword(s):  
Dna Polymerase ◽  
Gene Structure ◽  
Purification And Characterization ◽  
Dna Polymerase Β ◽  
Xiphophorus Maculatus

scholarly journals HUMAN MIXED LEUKOCYTE CULTURE: IDENTIFICATION OF THE PROLIFERATING LYMPHOCYTE SUBPOPULATION BY SEX CHROMOSOME MARKERS

1974 ◽  
Vol 140 (1) ◽  
pp. 54-60 ◽  
Author(s):  
Hans-Peter Lohrmann ◽  
Jacqueline Whang-Peng
Keyword(s):  
B Cells ◽  
Sex Chromosome ◽  
Lymphocyte Subpopulation ◽  
T And B Cells ◽  
Proliferating Cells ◽  
Chromosome Marker ◽  
Chromosome Markers ◽  
Opposite Sex ◽  
Culture Identification

The nature of the cells which proliferate in response to allogeneic histoincompatible lymphocytes in human mixed leukocyte cultures (MLC) was investigated. Direct information on the differentiation of proliferating cells was obtained in an in vitro chimeric system with T- and B-cell sex chromosome markers. Highly purified T and B cells were prepared from the peripheral blood of three pairs of HL-A genotype identical, MLC-negative siblings of opposite sex by E-rosette sedimentation techniques. Recombined T and B cells of the siblings were stimulated with allogeneic cells, and karyotype analysis of proliferating cells performed. 96% of the proliferating cells were found to carry the sex chromosome marker of the respective T-cell population. These results indicate that proliferation in human MLCs is a feature of T cells.

Sex chromosome marker: Clinical significance and DNA characterization

1991 ◽  
Vol 39 (1) ◽  
pp. 97-101 ◽  
Author(s):  
Virginia P. Johnson ◽  
Paul G. McDonough ◽  
Sau W. Cheung ◽  
Li Sun
Keyword(s):  
Clinical Significance ◽  
Sex Chromosome ◽  
Chromosome Marker ◽  
Dna Characterization
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