First demonstration of copper-plated through-package-via (TPV) reliability in ultra-thin 3D glass interposers with double-side component assembly

2015 ◽  
Author(s):  
Kaya Demir ◽  
Saumya Gandhi ◽  
Tomonori Ogawa ◽  
Raghu Pucha ◽  
Vanessa Smet ◽  
...  
Keyword(s):  
Side Component ◽  
Component Assembly

scholarly journals PAT for Continuous Chromatography Integrated into Continuous Manufacturing of Biologics towards Autonomous Operation

Processes ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 472
Author(s):  
Florian Lukas Vetter ◽  
Steffen Zobel-Roos ◽  
Jochen Strube
Keyword(s):  
Molecular Weight ◽  
Zero Point ◽  
Test System ◽  
Target Component ◽  
Array Detector ◽  
Continuous Manufacturing ◽  
Fluorescence Detector ◽  
Autonomous Operation ◽  
Side Component ◽  
Process Disturbances

This study proposes a reliable inline PAT concept for the simultaneous monitoring of different product components after chromatography. The feed for purification consisted of four main components, IgG monomer, dimer, and two lower molecular weight components of 4.4 kDa and 1 kDa molecular weight. The proposed measurement setup consists of a UV–VIS diode-array detector and a fluorescence detector. Applying this system, a R2 of 0.93 for the target component, a R2 of 0.67 for the dimer, a R2 of 0.91 for the first side component and a R2 of 0.93 for the second side component is achieved. Root mean square error for IgG monomer was 0.027 g/L, for dimer 0.0047 g/L, for side component 1 0.016 g/L and for the side component 2 0.014 g/L. The proposed measurement concept tracked component concentration reliably down to 0.05 g/L. Zero-point fluctuations were kept within a standard deviation of 0.018 g/L for samples with no IgG concentration but with side components present, allowing a reliable detection of the target component. The main reason inline concentration measurements have not been established yet, is the false-positive measurement of target components when side components are present. This problem was eliminated using the combination of fluorescence and UV–VIS data for the test system. The use of this measurement system is simulated for the test system, allowing an automatic fraction cut at 0.05 g/L. In this simulation a consistent yield of >99% was achieved. Process disturbances for processed feed volume, feed purity and feed IgG concentration can be compensated with this setup. Compared to a timed process control, yield can be increased by up to 12.5%, if unexpected process disturbances occur.

The Influence of Manufacturing Tolerances on Swirler Durability

2014 ◽  
Author(s):  
Nagaraja S. Rudrapatna ◽  
Richard R. Bohman ◽  
Jonathan K. Anderson ◽  
Rudolph Dudebout ◽  
Richard Hausen
Keyword(s):  
Damage Mechanism ◽  
Jet Fuel ◽  
Combustible Mixture ◽  
Fuel Injector ◽  
Component Level ◽  
Pareto Chart ◽  
Flow Features ◽  
Manufacturing Tolerances ◽  
Oxidation Damage ◽  
Component Assembly

Jet fuel flowing through the fuel injector is atomized and then mixed with high temperature compressed air flowing through the swirler to create a combustible mixture inside a gas turbine combustor. Individual geometric and flow features are carefully tuned at a component level to deliver optimum combustion performance. In a critical interface such as the fuel injector and swirler, manufacturing tolerances not only have an impact on combustor performance and operability but also on durability, as the relative position of the fuel injector to the swirler significantly impacts the swirler temperature. This paper studies the influence of manufacturing tolerances on component assembly and the resulting impact on swirler temperature. The oxidation damage mechanism of the swirler is used as a measure to assess swirler durability. A Pareto chart of the effect of manufacturing tolerances on metal temperature is used to highlight the key influencing parameters. Probability distribution associated with manufacturing tolerances is gathered with Monte Carlo simulation to guide the design.

scholarly journals Shock Pulse Shaping in a Small-Form Factor Velocity Amplifier

2010 ◽  
Vol 17 (6) ◽  
pp. 787-802 ◽  
Author(s):  
Gerard Kelly ◽  
Jeff Punch ◽  
Suresh Goyal ◽  
Michael Sheehy
Keyword(s):  
Pulse Shaping ◽  
Vertical Axis ◽  
Mechanical Shock ◽  
Practical Applications ◽  
Shock Testing ◽  
Acceleration Signal ◽  
High Acceleration ◽  
Component Assembly ◽  
Small Form Factor ◽  
Shock Pulses

This theme of this paper is the design and characterisation of a velocity amplifier (VAMP) machine for high-acceleration shock testing of micro-scale devices. The VAMP applies multiple sequential impacts to amplify velocity through a system of three progressively smaller masses constrained to move in the vertical axis. Repeatable, controlled, mechanical shock pulses are created through the metal-on-metal impact between pulse shaping test rods, which form part of the penultimate and ultimate masses. The objectives are to investigate the controllable parameters that affect the shock pulses induced on collision, namely; striker and incident test rod material; test rod length; pulse shaping mechanisms; and impact velocity. The optimum VAMP configuration was established as a 60 mm long titanium striker test rod and a 120 mm long titanium incident rod. This configuration exhibited an acceleration magnitude and a primary pulse duration range of 5,800–23,400 g and 28.0–44.0μs respectively. It was illustrated that the acceleration spectral content can be manipulated through control of the test rod material and length. This is critical in the context of practical applications, where it is postulated that the acceleration signal can be controlled to effectively excite specific components in a multi-component assembly affixed to the VAMP incident test rod.

scholarly journals Structural and Thermodynamic Analysis of a Three-Component Assembly Forming ortho-Iminophenylboronate Esters

2016 ◽  
Vol 81 (18) ◽  
pp. 8319-8330 ◽  
Author(s):  
Brette M. Chapin ◽  
Pedro Metola ◽  
Vincent M. Lynch ◽  
John F. Stanton ◽  
Tony D. James ◽  
...  
Keyword(s):  
Thermodynamic Analysis ◽  
Component Assembly

Some conceptual issues in component-assembly modelling

2001 ◽  
Vol 15 (2) ◽  
pp. 109-119 ◽  
Author(s):  
Mike Rosenman ◽  
Simeon J. Simoff
Keyword(s):  
Component Assembly

scholarly journals In-Process Measurement for the Process Control of the Real-Time Manufacturing of Tapered Roller Bearings

Materials ◽  
2018 ◽  
Vol 11 (8) ◽  
pp. 1371 ◽  
Author(s):  
Francisco Brosed ◽  
A. Zaera ◽  
Emilio Padilla ◽  
Fernando Cebrián ◽  
Juan Aguilar
Keyword(s):  
Real Time ◽  
Measurement Procedure ◽  
Axial Loads ◽  
Machining Processes ◽  
Process Measurement ◽  
Roller Bearings ◽  
Tapered Roller ◽  
Environmental Process ◽  
Tapered Roller Bearings ◽  
Component Assembly

Tapered roller bearings can accommodate high radial loads as well as high axial loads. The manufacturing process consists of machining processes for ring and component assembly. In this contribution, the parameters of influence on the measurement procedure were studied. These parameters of influence were classified as environmental, process, and machine parameters. The main objective of this work was to optimize the process using real-time measurements, which required the study of the influence of several parameters on the measurement uncertainty and how to correct their effects.

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