A New Mutation Analysis Method for Testing Java Exception Handling

2009 ◽  
Author(s):  
Changbing Ji ◽  
Zhenyu Chen ◽  
Baowen Xu ◽  
Ziyuan Wang
Keyword(s):  
Mutation Analysis ◽  
Exception Handling ◽  
Analysis Method ◽  
New Mutation

A Case of Congenital Glucose Galactose Malabsorption with a New Mutation in the SLC5A1 Gene

2020 ◽  
Author(s):  
Hasan Akduman ◽  
Dilek Dilli ◽  
Serdar Ceylaner
Keyword(s):  
Mutation Analysis ◽  
Autosomal Recessive ◽  
Glucose Transporter ◽  
Neonatal Period ◽  
Autosomal Recessive Disorder ◽  
Homozygous Mutation ◽  
New Mutation ◽  
Early Neonatal Period ◽  
Sodium Dependent ◽  
Hypernatremic Dehydration

AbstractCongenital glucose-galactose malabsorption (CGGM) is an autosomal recessive disorder originating from an abnormal transporter mechanism in the intestines. It was sourced from a mutation in the SLC5A1 gene, which encodes a sodium-dependent glucose transporter. Here we report a 2-day-old girl with CGGM who presented with severe hypernatremic dehydration due to diarrhea beginning in the first hours of life. Mutation analysis revealed a novel homozygous mutation NM_000343.3 c.127G > A (p.Gly43Arg) in the SLC5A1 gene. Since CGGM can cause fatal diarrhea in the early neonatal period, timely diagnosis of the disease seems to be essential.

scholarly journals Design and Generation of MLPA Probe Sets for Combined Copy Number and Small-Mutation Analysis of Human Genes: EGFR as an Example

2010 ◽  
Vol 10 ◽  
pp. 2003-2018 ◽  
Author(s):  
Malgorzata Marcinkowska ◽  
Kwok-Kin Wong ◽  
David J. Kwiatkowski ◽  
Piotr Kozlowski
Keyword(s):  
Mutation Analysis ◽  
Copy Number ◽  
Analysis Method ◽  
Copy Number Analysis ◽  
Short Oligonucleotide ◽  
Human Genes ◽  
Simple Protocol ◽  
Commercial Kits ◽  
Genomic Regions ◽  
Dependent Probe

Multiplex ligation-dependent probe amplification (MLPA) is a multiplex copy number analysis method that is routinely used to identify large mutations in many clinical and research labs. One of the most important drawbacks of the standard MLPA setup is a complicated, and therefore expensive, procedure of generating long MLPA probes. This drawback substantially limits the applicability of MLPA to those genomic regions for which ready-to-use commercial kits are available. Here we present a simple protocol for designing MLPA probe sets that are composed entirely of short oligonucleotide half-probes generated through chemical synthesis. As an example, we present the design and generation of an MLPA assay for parallel copy number and small-mutation analysis of theEGFRgene.

Mutation analysis of TBX22 reveals new mutation in Tunisian CPX family

2005 ◽  
Vol 14 (1) ◽  
pp. 23-25 ◽  
Author(s):  
Myriam Chaabouni ◽  
Nizar Smaoui ◽  
Neila Benneji ◽  
Ridha M??rad ◽  
Lamia Ben Jemaa ◽  
...  
Keyword(s):  
Mutation Analysis ◽  
New Mutation

scholarly journals Mutation Analysis Approach to Develop Reliable Object-Oriented Software

2014 ◽  
Vol 2014 ◽  
pp. 1-16 ◽  
Author(s):  
Monalisa Sarma
Keyword(s):  
Mutation Analysis ◽  
Object Oriented ◽  
Exception Handling ◽  
Analysis Approach ◽  
Test Cases ◽  
Large Set ◽  
Java Programming ◽  
Mutation Operators ◽  
Analysis Technique ◽  
Mutation Score

In general, modern programs are large and complex and it is essential that they should be highly reliable in applications. In order to develop highly reliable software, Java programming language developer provides a rich set of exceptions and exception handling mechanisms. Exception handling mechanisms are intended to help developers build robust programs. Given a program with exception handling constructs, for an effective testing, we are to detect whether all possible exceptions are raised and caught or not. However, complex exception handling constructs make it tedious to trace which exceptions are handled and where and which exceptions are passed on. In this paper, we address this problem and propose a mutation analysis approach to develop reliable object-oriented programs. We have applied a number of mutation operators to create a large set of mutant programs with different type of faults. We then generate test cases and test data to uncover exception related faults. The test suite so obtained is applied to the mutant programs measuring the mutation score and hence verifying whether mutant programs are effective or not. We have tested our approach with a number of case studies to substantiate the efficacy of the proposed mutation analysis technique.

A probabilistic analysis method for functional qualification under Mutation Analysis

2012 ◽  
Author(s):  
Hsiu-Yi Lin ◽  
Chun-Yao Wang ◽  
Shih-Chieh Chang ◽  
Yung-Chih Chen ◽  
Hsuan-Ming Chou ◽  
...  
Keyword(s):  
Mutation Analysis ◽  
Probabilistic Analysis ◽  
Analysis Method

scholarly journals A genome-wide mutation analysis method enabling high-throughput identification of chemical mutagen signatures

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Shoji Matsumura ◽  
Yurika Fujita ◽  
Masayuki Yamane ◽  
Osamu Morita ◽  
Hiroshi Honda
Keyword(s):  
Mutation Analysis ◽  
High Throughput ◽  
Chemical Mutagen ◽  
Analysis Method ◽  
Genome Wide ◽  
A Genome

Determination of haemophilia A carrier status by mutation analysis

Haemophilia ◽  
2001 ◽  
Vol 7 (1) ◽  
pp. 20-25 ◽  
Author(s):  
S. Oranwiroon ◽  
V. Akkarapatumwong ◽  
P. Pung-Amritt ◽  
A. Treesucon ◽  
G. Veerakul ◽  
...  
Keyword(s):  
Mutation Analysis ◽  
Carrier Status ◽  
Haemophilia A

homeodomain mutation analysis in patients with Müllerian system anomalies

1998 ◽  
Vol 5 (1) ◽  
pp. 140A-140A ◽  
Author(s):  
J STELLING ◽  
B BHAGAVATH ◽  
M GRAY ◽  
R REINDOLLAR
Keyword(s):  
Mutation Analysis
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