Basic Properties of Calcium Phosphate Cement Containing Chitosan in its Liquid Phase

2009 ◽  
Author(s):  
Hua Liu ◽  
Xiaofeng Chen ◽  
Changren Zhou ◽  
Hong Li
Keyword(s):  
Liquid Phase ◽  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Basic Properties

The pH-Dependent Properties of the Biphasic Calcium Phosphate for Bone Cements

2014 ◽  
Vol 21 ◽  
pp. 3-16 ◽  
Author(s):  
Nuan La Ong Srakaew ◽  
Sirirat Tubsungnoen Rattanachan
Keyword(s):  
Compressive Strength ◽  
Liquid Phase ◽  
Calcium Phosphate ◽  
Phase Analysis ◽  
Calcium Phosphate Cement ◽  
Biphasic Calcium Phosphate ◽  
Setting Time ◽  
Bone Cements ◽  
Apatite Formation ◽  
Apatite Cement

Self-setting calcium phosphate cement (CPC) has been used in bone repair and substitution due to their excellent biocompatibility, bioactive as well as simplicity of preparation and use. The inherent brittleness and slow degradation are the major disadvantages for the use of calcium phosphate cements. To improve the degradation for the traditional CPC, the apatite cement formula incorporated with β-tricalcium phosphate (β-TCP) with varying concentration were studied and the effect of the pH value of liquid phase on the properties of this new calcium phosphate cement formula was evaluated. The apatite cements containing β-TCP for 10 and 40 wt.% were mixed into the aqueous solution with different pH values and then aging in absolute humidity at 37°C for 7 days. The setting time and phase analysis of the biphasic calcium phosphate were determined as compared to the apatite cement. For proper medical application, the compressive strength, the phase analysis and the degradation of the CPC samples at pH 7.0 and 7.4 were evaluated after soaking in the simulated body fluid (SBF) at 37°C for 7 days. The results indicated that the properties of the samples such as the setting time, the compressive strength related to the phase analysis of the set cements. The high degradation of the CPC was found in the cement with increasing β-TCP addition due to the phase after setting. Apatite formation with oriented plate-like morphology was also found to be denser on the surface of the biphasic bone cements after soaking in SBF for 7 days. The obtained results indicated that the cement containing β-TCP mixed with the liquid phase at pH 7.4 could be considered as a highly biodegradable and bioactive bone cement, as compared to the traditional CPC.

Effects of added antibiotics on the basic properties of anti-washout-type fast-setting calcium phosphate cement

1998 ◽  
Vol 39 (2) ◽  
pp. 308-316 ◽  
Author(s):  
Masaaki Takechi ◽  
Youji Miyamoto ◽  
Kunio Ishikawa ◽  
Masaru Nagayama ◽  
Masayuki Kon ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Basic Properties

Effect of Protein Addition on the Setting Behaviour of a Calcium Phosphate Cement

2006 ◽  
Vol 309-311 ◽  
pp. 841-844
Author(s):  
S. Chauhan ◽  
M.P. Hofmann ◽  
R.M. Shelton
Keyword(s):  
Compressive Strength ◽  
Liquid Phase ◽  
Calcium Phosphate ◽  
Mechanical Strength ◽  
Calcium Phosphate Cement ◽  
Tricalcium Phosphate ◽  
Bovine Serum ◽  
Setting Time ◽  
Monocalcium Phosphate ◽  
Foetal Bovine Serum

This study investigated the influence of the addition of various proteins to the liquid phase (albumin, fibrinogen and foetal bovine serum (FBS)) on the mechanical strength and setting time of a brushite forming calcium phosphate cement. Additions of 1wt% protein to the liquid phase led to a deterioration in compressive strength of the set cement by up to 50%. The setting time was not affected by adding albumin and FBS but was increased by 50% with admixtures containing fibrinogen. The conversion of the reactants, β-tricalcium phosphate and monocalcium phosphate, to brushite was found to be unaffected by addition of up to 10wt% proteins.

Basic properties of calcium phosphate cement containing atelocollagen in its liquid or powder phases

Biomaterials ◽  
1998 ◽  
Vol 19 (7-9) ◽  
pp. 707-715 ◽  
Author(s):  
Youji Miyamoto ◽  
Kunio Ishikawa ◽  
Masaaki Takechi ◽  
Taketomo Toh ◽  
Tetsuya Yuasa ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Basic Properties

Meerwein-Ponndorf reduction of benzaldehyde over metal oxides

1980 ◽  
Vol 45 (7) ◽  
pp. 1937-1939 ◽  
Author(s):  
Lubomír Nondek ◽  
Jiří Sedláček
Keyword(s):  
Liquid Phase ◽  
Metal Oxides ◽  
Basic Properties

The Meerwein-Ponndorf reduction of benzaldehyde by 2-propanol in the liquid phase was studied in the presence of metal oxides as the catalysts. Except for aluminia, all the eight metal oxides tested were found to be nearly inactive. The activity of the aluminia-magnesia catalysts decreased with the decreasing aluminia content. No correlation was observed between the basic properties of the aluminia-magnesia catalysts and their activity in the reduction of benzaldehyde.

scholarly journals A bone replacement-type calcium phosphate cement that becomes more porous in vivo by incorporating a degradable polymer

2021 ◽  
Vol 32 (7) ◽  
Author(s):  
Akiyoshi Shimatani ◽  
Hiromitsu Toyoda ◽  
Kumi Orita ◽  
Yuta Ibara ◽  
Yoshiyuki Yokogawa ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Calcium Phosphate Cement ◽  
Alginic Acid ◽  
Setting Time ◽  
Zealand White Rabbit ◽  
Control Group ◽  
Degradable Polymer ◽  
Low Viscosity ◽  
Bone Replacement

AbstractThis study investigated whether mixing low viscosity alginic acid with calcium phosphate cement (CPC) causes interconnected porosity in the CPC and enhances bone replacement by improving the biological interactions. Furthermore, we hypothesized that low viscosity alginic acid would shorten the setting time of CPC and improve its strength. CPC samples were prepared with 0, 5, 10, and 20% low viscosity alginic acid. After immersion in acetate buffer, possible porosification in CPC was monitored in vitro using scanning electron microscopy (SEM), and the setting times and compressive strengths were measured. In vivo study was conducted by placing CPC in a hole created on the femur of New Zealand white rabbit. Microcomputed tomography and histological examination were performed 6 weeks after implantation. SEM images confirmed that alginic acid enhanced the porosity of CPC compared to the control, and the setting time and compressive strength also improved. When incorporating a maximum amount of alginic acid, the new bone mass was significantly higher than the control group (P = 0.0153). These biological responses are promising for the translation of these biomaterials and their commercialization for clinic applications.

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