scholarly journals Dynamic Characteristics of a Mechanical Ventilation System With Spontaneous Breathing

IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 172847-172859 ◽  
Author(s):  
Liming Hao ◽  
Yan Shi ◽  
Maolin Cai ◽  
Shuai Ren ◽  
Yixuan Wang ◽  
...  
2016 ◽  
Vol 2016 ◽  
pp. 1-13 ◽  
Author(s):  
Dongkai Shen ◽  
Qian Zhang ◽  
Yan Shi

In recent studies on the dynamic characteristics of ventilation system, it was considered that human had only one lung, and the coupling effect of double lungs on the air flow can not be illustrated, which has been in regard to be vital to life support of patients. In this article, to illustrate coupling effect of double lungs on flow dynamics of mechanical ventilation system, a mathematical model of a mechanical ventilation system, which consists of double lungs and a bi-level positive airway pressure (BIPAP) controlled ventilator, was proposed. To verify the mathematical model, a prototype of BIPAP system with a double-lung simulators and a BIPAP ventilator was set up for experimental study. Lastly, the study on the influences of key parameters of BIPAP system on dynamic characteristics was carried out. The study can be referred to in the development of research on BIPAP ventilation treatment and real respiratory diagnostics.


2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Yan Shi ◽  
Shuai Ren ◽  
Maolin Cai ◽  
Weiqing Xu ◽  
Qiyou Deng

Mechanical ventilation is an important life support treatment of critically ill patients, and air pressure dynamics of human lung affect ventilation treatment effects. In this paper, in order to obtain the influences of seven key parameters of mechanical ventilation system on the pressure dynamics of human lung, firstly, mechanical ventilation system was considered as a pure pneumatic system, and then its mathematical model was set up. Furthermore, to verify the mathematical model, a prototype mechanical ventilation system of a lung simulator was proposed for experimental study. Last, simulation and experimental studies on the air flow dynamic of the mechanical ventilation system were done, and then the pressure dynamic characteristics of the mechanical system were obtained. The study can be referred to in the pulmonary diagnostics, treatment, and design of various medical devices or diagnostic systems.


Energies ◽  
2021 ◽  
Vol 14 (11) ◽  
pp. 3008
Author(s):  
Agnieszka W. Lach ◽  
André V. Gaathaug

This paper presents a series of experiments on the effectiveness of existing mechanical ventilation systems during accidental hydrogen releases in confined spaces, such as underground garages. The purpose was to find the mass flow rate limit, hence the TPRD diameter limit, that will not require a change in the ventilation system. The experiments were performed in a 40 ft ISO container in Norway, and hydrogen gas was used in all experiments. The forced ventilation system was installed with a standard 315 mm diameter outlet. The ventilation parameters during the investigation were British Standard with 10 ACH and British Standard with 6 ACH. The hydrogen releases were obtained through 0.5 mm and 1 mm nozzles from different hydrogen reservoir pressures. Both types of mass flow, constant and blowdown, were included in the experimental matrix. The analysis of the hydrogen concentration of the created hydrogen cloud in the container shows the influence of the forced ventilation on hydrogen releases, together with TPRD diameter and reservoir pressure. The generated experimental data will be used to validate a CFD model in the next step.


2010 ◽  
Vol 36 (8) ◽  
pp. 1427-1435 ◽  
Author(s):  
Dietrich Henzler ◽  
Nadine Hochhausen ◽  
Ralf Bensberg ◽  
Alexander Schachtrupp ◽  
Sonja Biechele ◽  
...  

2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110100
Author(s):  
Ju Gong ◽  
Bibo Zhang ◽  
Xiaowen Huang ◽  
Bin Li ◽  
Jian Huang

Objective Clinicians cannot precisely determine the time for withdrawal of ventilation. We aimed to evaluate the performance of driving pressure (DP)×respiratory rate (RR) to predict the outcome of weaning. Methods Plateau pressure (Pplat) and total positive end-expiratory pressure (PEEPtot) were measured during mechanical ventilation with brief deep sedation and on volume-controlled mechanical ventilation with a tidal volume of 6 mL/kg and a PEEP of 0 cmH2O. Pplat and PEEPtot were measured by patients holding their breath for 2 s after inhalation and exhalation, respectively. DP was determined as Pplat minus PEEPtot. The rapid shallow breathing index was measured from the ventilator. The highest RR was recorded within 3 minutes during a spontaneous breathing trial. Patients who tolerated a spontaneous breathing trial for 1 hour were extubated. Results Among the 105 patients studied, 44 failed weaning. During ventilation withdrawal, DP×RR was 136.7±35.2 cmH2O breaths/minute in the success group and 230.2±52.2 cmH2O breaths/minute in the failure group. A DP×RR index >170.8 cmH2O breaths/minute had a sensitivity of 93.2% and specificity of 88.5% to predict failure of weaning. Conclusions Measurement of DP×RR during withdrawal of ventilation may help predict the weaning outcome. A high DP×RR increases the likelihood of weaning failure. Statement: This manuscript was previously posted as a preprint on Research Square with the following link: https://www.researchsquare.com/article/rs-15065/v3 and DOI: 10.21203/rs.2.24506/v3


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