Innovations in two-photon deep tissue microscopy

1999 ◽  
Vol 18 (5) ◽  
pp. 23-30 ◽  
Author(s):  
C. Buehler ◽  
Ki Hean Kim ◽  
C.Y. Dong ◽  
B.R. Masters ◽  
P.T.C. So
Keyword(s):  
Deep Tissue ◽  
Two Photon ◽  
Tissue Microscopy

scholarly journals In vivo deep-tissue microscopy with UCNP/Janus-dendrimers as imaging probes: resolution at depth and feasibility of ratiometric sensing

Nanoscale ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 2657-2672 ◽  
Author(s):  
Shane Plunkett ◽  
Mirna El Khatib ◽  
İkbal Şencan ◽  
Jason E. Porter ◽  
Anand T. N. Kumar ◽  
...  
Keyword(s):  
Energy Transfer ◽  
High Resolution ◽  
Excitation Energy Transfer ◽  
Deep Tissue ◽  
Ratiometric Sensing ◽  
Two Photon ◽  
Imaging Probes ◽  
Tissue Microscopy ◽  
The Brain

UCNP/Janus-dendrimers enable high-resolution two-photon imaging in the brain up to 1 mm-deep under low-power CW excitation. However, ratiometric sensing using UCNPs and excitation energy transfer is strongly obstructed by tissue absorption.

scholarly journals The Power of Single and Multibeam Two-Photon Microscopy for High-Resolution and High-Speed Deep Tissue and Intravital Imaging

2007 ◽  
Vol 93 (7) ◽  
pp. 2519-2529 ◽  
Author(s):  
Raluca Niesner ◽  
Volker Andresen ◽  
Jens Neumann ◽  
Heinrich Spiecker ◽  
Matthias Gunzer
Keyword(s):  
High Resolution ◽  
High Speed ◽  
Intravital Imaging ◽  
Deep Tissue ◽  
Two Photon Microscopy ◽  
Two Photon

Efficient two-photon luminescence for cellular imaging using biocompatible nitrogen-doped graphene quantum dots conjugated with polymers

Nanoscale ◽  
2018 ◽  
Vol 10 (1) ◽  
pp. 109-117 ◽  
Author(s):  
Ping-Ching Wu ◽  
Jiu-Yao Wang ◽  
Wen-Lung Wang ◽  
Chia-Yuan Chang ◽  
Chia-Hung Huang ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Contrast Agent ◽  
Graphene Quantum Dots ◽  
Cellular Imaging ◽  
Deep Tissue ◽  
Nitrogen Doped ◽  
Two Photon ◽  
Nitrogen Doped Graphene ◽  
Doped Graphene

N-doped GQDs conjugated with polymers demonstrate impressive two-photon properties and stability, and can be used as a contrast agent in deep tissue bioimaging.

scholarly journals Ultrabright red AIEgens for two-photon vascular imaging with high resolution and deep penetration

2018 ◽  
Vol 9 (10) ◽  
pp. 2705-2710 ◽  
Author(s):  
Wei Qin ◽  
Pengfei Zhang ◽  
Hui Li ◽  
Jacky W. Y. Lam ◽  
Yuanjing Cai ◽  
...  
Keyword(s):  
High Resolution ◽  
Vascular Imaging ◽  
Tissue Imaging ◽  
Deep Penetration ◽  
High Contrast ◽  
Deep Tissue ◽  
Two Photon ◽  
High Penetration ◽  
Deep Tissue Imaging

A successful strategy for the design of ultrabright red luminogens with aggregation-induced emission (AIE) features is reported. The AIE dots can be utilized as efficient fluorescent probes for in vivo deep-tissue imaging with high penetration depth and high contrast.

scholarly journals Extremely High Brightness from Polymer-Encapsulated Quantum Dots for Two-photon Cellular and Deep-tissue Imaging

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Yanyan Fan ◽  
Helin Liu ◽  
Rongcheng Han ◽  
Lu Huang ◽  
Hao Shi ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Tissue Imaging ◽  
Deep Tissue ◽  
High Brightness ◽  
Two Photon ◽  
Deep Tissue Imaging

scholarly journals NIR in, far-red out: developing a two-photon fluorescent probe for tracking nitric oxide in deep tissue

2016 ◽  
Vol 7 (8) ◽  
pp. 5230-5235 ◽  
Author(s):  
Zhiqiang Mao ◽  
Wenqi Feng ◽  
Zhen Li ◽  
Lingyu Zeng ◽  
Weijie Lv ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Fluorescent Probe ◽  
Deep Tissue ◽  
Two Photon

The first far-red emissive, two-photon fluorescent probe for nitric oxide was rationally designed and applied in detecting nitric oxide in both cells and tissues.

Deep tissue two-photon microscopy

2005 ◽  
Vol 2 (12) ◽  
pp. 932-940 ◽  
Author(s):  
Fritjof Helmchen ◽  
Winfried Denk
Keyword(s):  
Deep Tissue ◽  
Two Photon Microscopy ◽  
Two Photon

scholarly journals Photodamage in deep tissue two-photon optical biopsy of human skin

2014 ◽  
Vol 8 (10) ◽  
pp. 816-825 ◽  
Author(s):  
Luca Dalbosco ◽  
Giulia Zanini ◽  
Elvira D'Amato ◽  
Francesco Tessarolo ◽  
Sebastiana Boi ◽  
...  
Keyword(s):  
Human Skin ◽  
Optical Biopsy ◽  
Deep Tissue ◽  
Two Photon
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