Segmentation of brain parenchyma and cerebrospinal fluid in multispectral magnetic resonance images

1995 ◽  
Vol 14 (2) ◽  
pp. 339-349 ◽  
Author(s):  
A. Lundervold ◽  
G. Storvik
2019 ◽  
Author(s):  
Yake Zheng ◽  
Peng Zhao ◽  
yajun lian ◽  
Lihao Li ◽  
Yuan Chen ◽  
...  

Abstract Background We set out to investigate the characteristics and factors related to non-inflammation cerebrospinal fluid (CSF) and normal brain magnetic resonance images (MRI) of autoimmune encephalitis (AE) in patients. Methods The distribution and characteristics of brain MRI and CSF in 124 patients who were living with anti-NMDAR(71), LGI1(26),CASPR2(4),GABAR(23) encephalitis and who had been admitted between October 2016 and May 2018 were analyzed prospectively. Results 12 of the 124 patients(1%) had a normal MRI and non-inflammation CSF.Ten of them were LGI1(83%),while the remaining 1 patient was NMDAR(8.3%),1 patient was CASPR2(8.3%).The clinical symptoms including epilepsy, psychosis, cognitive disorders, conscious disorders, headache, faciobrachial dystonic seizure (FBDS), speech disorders and hypoventilation. AE with non-inflammation CSF and normal MRI with good clinical prognosis. The median modified Rankin Scale (mRS) was low, and recurrence rate was also low. Conclusion The clinical manifestations of on-inflammation CSF and brain MRI-negative patients with AE are not specific, but suggest a better prognosis and a lower recurrence rates.


2018 ◽  
Vol 26 (1) ◽  
pp. 82-85
Author(s):  
Ahmet Gökyar ◽  
Cengiz Cokluk

Background. Detection of a deep-seated lesion located in the brain parenchyma and major neuroanatomical sites is a critical issue in neurosurgery. Some neurosurgical cranial navigation systems have been developed that are available; however, some preparation is necessary, including the installation of complex computer software programs and obtaining specific neuroradiological images. Objective. The purpose of this experimental study was to design and evaluate a superficial stereotaxic frameless lesion locator in order to localize mass lesions within the brain. Methods. A superficial stereotaxic frameless lesion locator system was designed using cardboard and the Cartesian coordinate system as a reference framework. This material was used in a model creating printed magnetic resonance images in the superficially marking of the lesion. This material easily located the lesion placement and superficially projected the lesion location. Results. The results of this study revealed that the superficial stereotaxic frameless lesion location procedure using a coordinate cardboard locator is a safe, fast, and simple procedure. This procedure provides an accurate means of locating the target lesion seated within the brain parenchyma. When compared with other models, we found that this device is reliable and has a high rate of superficial lesion detection. Conclusion. A superficial lesion locator may be used in clinical practice. This experimental study demonstrated the usability and reliability of the procedure. Additional detailed investigations are necessary to improve the procedure.


2004 ◽  
Vol 100 (1) ◽  
pp. 106-114 ◽  
Author(s):  
Hideyuki Higuchi ◽  
Jyun-ichi Hirata ◽  
Yushi Adachi ◽  
Tomiei Kazama

Background The current study was designed to investigate the influence of lumbosacral cerebrospinal fluid (CSF) density, velocity, and volume on the extent and duration of plain bupivacaine spinal anesthesia. Methods Forty-one patients scheduled to undergo orthopedic surgery with spinal block were enrolled. Lumbosacral CSF volumes were calculated from low thoracic, lumbar, and sacral axial magnetic resonance images. CSF velocity at the L3-L4 level was derived from phase-contrast magnetic resonance images. Spinal anesthesia was performed in the lateral decubitus position. CSF (2 ml) was sampled to measure CSF density before injection of 3 ml plain bupivacaine (0.5%). Statistical correlation coefficients (rho) between CSF characteristics and measurements of spinal anesthesia were assessed by Spearman rank correlation. In addition, stepwise multiple linear regression models were used to select important predictors of measures of spinal anesthesia. Results There was a significant correlation between CSF density and peak sensory block level (rho = 0.33, P = 0.034). Lumbosacral CSF volume inversely correlated with peak sensory block level (rho = -0.65, P < 0.0001) and positively correlated with onset time of complete motor block (rho = 0.42, P = 0.008). CSF volume also inversely correlated with time required for regression of the sensory block to L1 (rho = -0.35, P = 0.026) and L2 (rho = -0.33, P = 0.039). There was a significant inverse correlation between peak diastolic CSF velocity and duration of motor blockade (rho = -0.44, P = 0.005). Multiple regression analysis revealed that weight and CSF volume significantly contributed to the peak sensory block level (R2 = 0.46). Conclusions These findings indicate that CSF density and volume influence the spread of spinal anesthesia with plain bupivacaine and that CSF volume also influences the duration of spinal anesthesia. CSF velocity might also influence the duration of plain bupivacaine spinal anesthesia.


1996 ◽  
Vol 85 (4) ◽  
pp. 685-688 ◽  
Author(s):  
Jerry Bauer ◽  
Roger F. Johnson ◽  
Joseph M. Levy ◽  
Donald V. Pojman ◽  
John R. Ruge

✓ Intracranial tuberculomas generally present as either solitary or multiple lesions in the brain parenchyma. They are characterized by a ring-enhancing area on either computerized tomography scans or magnetic resonance images. A case is presented in which an intracranial tuberculoma was dural based and had an appearance similar to an en plaque meningioma.


2003 ◽  
Vol 98 (4) ◽  
pp. 903-907 ◽  
Author(s):  
Dennis A. Nowak ◽  
Sven-Olaf Rodiek ◽  
Jürgen Zinner ◽  
Albrecht Guhlmann ◽  
Helge Topka

✓ The syndrome of spontaneous intracranial hypotension is characterized by orthostatic headaches in conjunction with reduced cerebrospinal fluid (CSF) pressure or CSF volume, and characteristic magnetic resonance (MR) imaging findings. A 50-year-old man presented with a 1-year history of paroxysmal ataxia of gait and short attacks of blurred vision when he stood up from a recumbent position and began to walk. Orthostatic headache was not a feature of his clinical presentation. Magnetic resonance images of the brain revealed diffuse enhancement of the dura mater and hygromas over both cerebral convexities. Magnetic resonance images of the spine demonstrated dilated cervical epidural veins and dilation of the perimedullary veins. Radionuclide cisternography identified a CSF leakage that was localized to the T12—L1 level on subsequent myelograms and on computerized tomography scans obtained after the myelograms. An epidural blood patch was administered and visualized with tungsten powder. The patient's clinical symptoms and sites of disease on imaging completely resolved. The unusual clinical presentation in this case—paroxysmal ataxia of gait, lack of orthostatic headaches, and dilated epidural and perimedullary venous plexus—supports a recently noted broadening of both the clinical and imaging characteristics of spontaneous intracranial hypovolemia.


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