Normalization of Functional Magnetic Resonance Images by Classified Cerebrospinal Fluid Cluster

2006 ◽  
Author(s):  
Zhenghui Hu ◽  
Pengcheng Shi
Keyword(s):  
Cerebrospinal Fluid ◽  
Magnetic Resonance ◽  
Magnetic Resonance Images ◽  
Functional Magnetic Resonance

Non-inflammation cerebrospinal fluid and normal brain magnetic resonance images of Autoimmune encephalits

2019 ◽  
Author(s):  
Yake Zheng ◽  
Peng Zhao ◽  
yajun lian ◽  
Lihao Li ◽  
Yuan Chen ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Magnetic Resonance ◽  
Clinical Symptoms ◽  
Brain Mri ◽  
Clinical Manifestations ◽  
Speech Disorders ◽  
Magnetic Resonance Images ◽  
Normal Brain ◽  
Recurrence Rates ◽  
Clinical Prognosis

Abstract Background We set out to investigate the characteristics and factors related to non-inflammation cerebrospinal fluid (CSF) and normal brain magnetic resonance images (MRI) of autoimmune encephalitis (AE) in patients. Methods The distribution and characteristics of brain MRI and CSF in 124 patients who were living with anti-NMDAR(71), LGI1(26),CASPR2(4),GABAR(23) encephalitis and who had been admitted between October 2016 and May 2018 were analyzed prospectively. Results 12 of the 124 patients(1%) had a normal MRI and non-inflammation CSF.Ten of them were LGI1(83%),while the remaining 1 patient was NMDAR(8.3%),1 patient was CASPR2(8.3%).The clinical symptoms including epilepsy, psychosis, cognitive disorders, conscious disorders, headache, faciobrachial dystonic seizure (FBDS), speech disorders and hypoventilation. AE with non-inflammation CSF and normal MRI with good clinical prognosis. The median modified Rankin Scale (mRS) was low, and recurrence rate was also low. Conclusion The clinical manifestations of on-inflammation CSF and brain MRI-negative patients with AE are not specific, but suggest a better prognosis and a lower recurrence rates.

scholarly journals Functional Magnetic Resonance Imaging and Somatosensory Evoked Potentials in Rats with a Neonatally Induced Freeze Lesion of the Somatosensory Cortex

2004 ◽  
Vol 24 (12) ◽  
pp. 1409-1418 ◽  
Author(s):  
Wolfram Schwindt ◽  
Michael Burke ◽  
Frank Pillekamp ◽  
Heiko J. Luhmann ◽  
Mathias Hoehn
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Evoked Potentials ◽  
Somatosensory Cortex ◽  
Somatosensory Evoked Potentials ◽  
Magnetic Resonance Images ◽  
Projection Area ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging

Brain plasticity is an important mechanism for functional recovery from a cerebral lesion. The authors aimed to visualize plasticity in adult rats with a neonatal freeze lesion in the somatosensory cortex using functional magnetic resonance imaging (fMRI), and hypothesized activation outside the primary projection area. A freeze lesion was induced in the right somatosensory cortex of newborn Wistar rats (n = 12). Sham-operated animals (n = 7) served as controls. After 6 or 7 months, a neurologic examination was followed by recording of somatosensory evoked potentials (SSEPs) and magnetic resonance experiments (anatomical images, fMRI with blood oxygen level–dependent contrast and perfusion-weighted imaging) with electrical forepaw stimulation under α-chloralose anesthesia. Lesioned animals had no obvious neurologic deficits. Anatomical magnetic resonance images showed a malformed cortex or hyperintense areas (cysts) in the lesioned hemisphere. SSEPs were distorted and smaller in amplitude, and fMRI activation was significantly weaker in the lesioned hemisphere. Only in a few animals were cortical areas outside the primary sensory cortex activated. The results are discussed in respect to an apparent absence of plasticity, loss of excitable tissue, the excitability of the lesioned hemisphere, altered connectivity, and a disturbed coupling of increased neuronal activity to the hemodynamic response.

Lipsia—a new software system for the evaluation of functional magnetic resonance images of the human brain

2001 ◽  
Vol 25 (6) ◽  
pp. 449-457 ◽  
Author(s):  
Gabriele Lohmann ◽  
Karsten Müller ◽  
Volker Bosch ◽  
Heiko Mentzel ◽  
Sven Hessler ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Human Brain ◽  
Magnetic Resonance Images ◽  
Software System ◽  
Functional Magnetic Resonance

scholarly journals Changes in extra-striatal functional connectivity in patients with schizophrenia in a psychotic episode

2017 ◽  
Vol 210 (1) ◽  
pp. 75-82 ◽  
Author(s):  
Henning Peters ◽  
Valentin Riedl ◽  
Andrei Manoliu ◽  
Martin Scherr ◽  
Dirk Schwerthöffer ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Magnetic Resonance ◽  
Functional Connectivity ◽  
Resting State ◽  
Ventral Striatum ◽  
Magnetic Resonance Images ◽  
Anterior Insula ◽  
Psychotic Episode ◽  
Functional Magnetic Resonance ◽  
Intrinsic Connectivity

BackgroundIn patients with schizophrenia in a psychotic episode, intra-striatal intrinsic connectivity is increased in the putamen but not ventral striatum. Furthermore, multimodal changes have been observed in the anterior insula that interact extensively with the putamen.AimsWe hypothesised that during psychosis, putamen extra-striatal functional connectivity is altered with both the anterior insula and areas normally connected with the ventral striatum (i.e. altered functional connectivity distinctiveness of putamen and ventral striatum).MethodWe acquired resting-state functional magnetic resonance images from 21 patients with schizophrenia in a psychotic episode and 42 controls.ResultsPatients had decreased functional connectivity: the putamen with right anterior insula and dorsal prefrontal cortex, the ventral striatum with left anterior insula. Decreased functional connectivity between putamen and right anterior insula was specifically associated with patients' hallucinations. Functional connectivity distinctiveness was impaired only for the putamen.ConclusionsResults indicate aberrant extra-striatal connectivity during psychosis and a relationship between reduced putamen–right anterior insula connectivity and hallucinations. Data suggest that altered intrinsic connectivity links striatal and insular pathophysiology in psychosis.

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