Practical iterative reconstruction methods for quantitative cardiac SPECT image reconstruction

1994 ◽  
Vol 41 (1) ◽  
pp. 325-330
Author(s):  
B.M.W. Tsui ◽  
Xide Zhao
2019 ◽  
Vol 7 (2A) ◽  
Author(s):  
Melissa Furlaneto Lellis Leite ◽  
Marilia Alves dos Reis ◽  
Cássio Miri Oliveira ◽  
Mario Luiz Vieira Castiglioni ◽  
Rodrigo Affonseca Bressan

TRODAT-1 is a radiopharmaceutical derived from tropane and linked to tecnecium-99m ([99mTc] TRODAT-1) has been used in studies of dopamine transporter (DAT) in central nervous system. Associated with the SPECT technique of acquisition, is able to detect changes in neurological disorders like Parkinson´s disease, evaluating the binding potential (BP) of DAT. The aim of this study was to evaluate the influence of the image reconstruction methods, Filtered Back Projection (FBP) and iterative reconstruction (OSEM), in BP values at the striatal region in 30 healthy volunteers. Images were analyzed by visual inspection and semi-quantitative analysis. Regions of interest (ROI) were made over striatal areas on both sides. Nonparametric Wilcoxon statistical analysis was performed between the BP values from the FBP and OSEM methods. Our results showed that the reconstruction methods have a statistical significant BP values difference in the total striatum (Z = -2,2787 p = 0.005), right striatum (Z = -2,602 p = 0.009) and left striatum (Z= 2,746 p = 0.006). The effect size was calculated to see if there influence in this test: the "large effect size" for all measurements was observed (total striatum r= -0.51; right striatum r= -0.48; left striatum r= -0.50). FBP is the usual method of reconstruction for brain SPECT images, and our results showed influence of the OSEM method in BP. It is concluded that the method of image reconstruction adopted should be standardized to avoid incorrect evaluations of BP values using [99mTc]TRODAT-1.


2012 ◽  
Vol 68 (4) ◽  
pp. 404-412 ◽  
Author(s):  
Tadanori Takata ◽  
Katsuhiro Ichikawa ◽  
Hiroyuki Hayashi ◽  
Wataru Mitsui ◽  
Keita Sakuta ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Maria Lyra ◽  
Agapi Ploussi ◽  
Maritina Rouchota ◽  
Stella Synefia

Nuclear cardiac imaging is a noninvasive, sensitive method providing information on cardiac structure and physiology. Single photon emission tomography (SPECT) evaluates myocardial perfusion, viability, and function and is widely used in clinical routine. The quality of the tomographic image is a key for accurate diagnosis. Image filtering, a mathematical processing, compensates for loss of detail in an image while reducing image noise, and it can improve the image resolution and limit the degradation of the image. SPECT images are then reconstructed, either by filter back projection (FBP) analytical technique or iteratively, by algebraic methods. The aim of this study is to review filters in cardiac 2D, 3D, and 4D SPECT applications and how these affect the image quality mirroring the diagnostic accuracy of SPECT images. Several filters, including the Hanning, Butterworth, and Parzen filters, were evaluated in combination with the two reconstruction methods as well as with a specified MatLab program. Results showed that for both 3D and 4D cardiac SPECT the Butterworth filter, for different critical frequencies and orders, produced the best results. Between the two reconstruction methods, the iterative one might be more appropriate for cardiac SPECT, since it improves lesion detectability due to the significant improvement of image contrast.


1997 ◽  
Vol 44 (3) ◽  
pp. 1336-1341 ◽  
Author(s):  
W. Xia ◽  
S.J. Glick ◽  
Tin-Su Pan ◽  
E.J. Soares ◽  
Der-Shan Luo

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