Quantitative evaluation of long-term locomotor activity of rats

2002 ◽  
Vol 51 (2) ◽  
pp. 393-397 ◽  
Author(s):  
A. Jobbagy ◽  
L. Gyongy ◽  
E. Monos
Amyloid ◽  
2002 ◽  
Vol 9 (2) ◽  
pp. 126-133 ◽  
Author(s):  
Mamede de Carvalho ◽  
Isabel Conceiçato ◽  
Carla Bentes ◽  
M. L. Sales Luis

IEEE Access ◽  
2020 ◽  
Vol 8 ◽  
pp. 111420-111432
Author(s):  
Mingyue Li ◽  
Zhenhai Gao ◽  
Fei Gao ◽  
Tianyao Zhang ◽  
Xingtai Mei ◽  
...  

2017 ◽  
Vol 270 ◽  
pp. 183-188
Author(s):  
Dagmar Jandová

Conventional (CCT) and accelerated (ACT) creep tests of a weld joint made of COST F and COST FB2 steels were carried out over a temperature range from 550 °C to 650 °C. Fracturing of the crept specimens was located in the heat affected zone (HAZ) of the F steel. Two specimens were selected after CCT and ACT for quantitative evaluation of the precipitates and compared to the weld joint in as-received conditions. Scanning and transmission electron micrographs were used to measure the precipitate size. Both methods were compared and the accuracy of the results was discussed. It was concluded that ACT can simulate the precipitation of chromium carbides and structure recovery during long term creep exposures. However, precipitation of Laves phase during CCT was not recorded after ACT. Therefore, it is difficult to use ACT in this experiment for estimating the long term creep strength.


2001 ◽  
Vol 26 (12) ◽  
pp. 1317-1332 ◽  
Author(s):  
Jeffrey D. Niemann ◽  
Nicole M. Gasparini ◽  
Gregory E. Tucker ◽  
Rafael L. Bras

1989 ◽  
Vol 98 (4) ◽  
pp. 448-452 ◽  
Author(s):  
Charanjit S. Aulakh ◽  
Joseph Zohar ◽  
Krystyna M. Wozniak ◽  
James L. Hill ◽  
Dennis L. Murphy

Endocrinology ◽  
2007 ◽  
Vol 148 (11) ◽  
pp. 5165-5172 ◽  
Author(s):  
Zeina S. Malek ◽  
Dominique Sage ◽  
Paul Pévet ◽  
Sylvie Raison

Tryptophan hydroxylase (TPH, the rate-limiting enzyme of serotonin synthesis) protein and mRNA levels display a circadian expression in the rat dorsal and median raphe. These patterns suggest a rhythmic synthesis of serotonin under the control of the master clock of suprachiasmatic nuclei. In the present study, we examined the involvement of endocrine and behavioral output signals of the master clock upon the Tph2 mRNA levels by quantitative in situ hybridization. In the absence of adrenals, a complete suppression of Tph2 mRNA rhythm was observed in dorsal and median raphe over 24 h. The restoration of corticosterone daily variations in adrenalectomized rats induced a Tph2 mRNA rhythmic pattern de novo, indicating that Tph2 mRNA rhythm is dependent upon daily fluctuations of glucocorticoids. Enhanced voluntary locomotor activity during 6 wk increased the level of Tph2 mRNA in both raphe nuclei of control rats without concomitant increase of corticosterone plasma levels. Moreover, this long-term enhanced locomotor activity was able to restore significant variation of Tph2 mRNA in adrenalectomized rats. In conclusion, both endocrine and behavioral cues can modulate Tph2 expression in dorsal and median raphe. The corticosterone surge acts as a rhythmic cue that induces the rhythmic expression of Tph2 in the raphe neurons. On the other hand, long-term exercise modulates the expression levels of this gene. Thus, the serotonin neurons are a target for both endocrine and behavioral circadian cues, and the serotoninergic input to the suprachiasmatic nuclei might feedback and influence the functioning of the clock itself.


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