In vivo quantification of a homogeneous brain deformation model for updating preoperative images during surgery

2000 ◽  
Vol 47 (2) ◽  
pp. 266-273 ◽  
Author(s):  
M.I. Miga ◽  
K.D. Paulsen ◽  
P.J. Hoopes ◽  
F.E. Kennedy ◽  
A. Hartov ◽  
...  
Author(s):  
Yangyang Zhang ◽  
Bingwei Lu ◽  
Chaofeng Lü ◽  
Xue Feng

Self-powered implantable devices with flexible energy harvesters are of significant interest due to their potential to solve the problem of limited battery life and surgical replacement. The flexible electronic devices made of piezoelectric materials have been employed to harvest energy from the motion of biological organs. Experimental measurements show that the output voltage of the device mounted on porcine left ventricle in chest closed environment decreases significantly compared to the case of chest open. A restricted-space deformation model is proposed to predict the impeding effect of pleural cavity, surrounding tissues, as well as respiration on the efficiency of energy harvesting from heartbeat using flexible piezoelectric devices. The analytical solution is verified by comparing theoretical predictions to experimental measurements. A simple scaling law is established to analyse the intrinsic correlations between the normalized output power and the combined system parameters, i.e. the normalized permitted space and normalized electrical load. The results may provide guidelines for optimization of in vivo energy harvesting from heartbeat or the motions of other biological organs using flexible piezoelectric energy harvesters.


2018 ◽  
Vol 140 (3) ◽  
Author(s):  
Lee F. Gabler ◽  
Hamed Joodaki ◽  
Jeff R. Crandall ◽  
Matthew B. Panzer

Linking head kinematics to injury risk has been the focus of numerous brain injury criteria. Although many early forms were developed using mechanics principles, recent criteria have been developed using empirical methods based on subsets of head impact data. In this study, a single-degree-of-freedom (sDOF) mechanical analog was developed to parametrically investigate the link between rotational head kinematics and brain deformation. Model efficacy was assessed by comparing the maximum magnitude of displacement to strain-based brain injury predictors from finite element (FE) human head models. A series of idealized rotational pulses covering a broad range of acceleration and velocity magnitudes (0.1–15 krad/s2 and 1–100 rad/s) with durations between 1 and 3000 ms were applied to the mechanical models about each axis of the head. Results show that brain deformation magnitude is governed by three categories of rotational head motion each distinguished by the duration of the pulse relative to the brain's natural period: for short-duration pulses, maximum brain deformation depended primarily on angular velocity magnitude; for long-duration pulses, brain deformation depended primarily on angular acceleration magnitude; and for pulses relatively close to the natural period, brain deformation depended on both velocity and acceleration magnitudes. These results suggest that brain deformation mechanics can be adequately explained by simple mechanical systems, since FE model responses and experimental brain injury tolerances exhibited similar patterns to the sDOF model. Finally, the sDOF model was the best correlate to strain-based responses and highlighted fundamental limitations with existing rotational-based brain injury metrics.


Author(s):  
Arnold D. Gomez ◽  
Andrew Knutsen ◽  
Deva Chan ◽  
Yuan-Chiao Lu ◽  
Dzung L. Pham ◽  
...  
Keyword(s):  

2020 ◽  
Vol 1 ◽  
pp. 100015 ◽  
Author(s):  
Andrew K Knutsen ◽  
Arnold D. Gomez ◽  
Mihika Gangolli ◽  
Wen-Tung Wang ◽  
Deva Chan ◽  
...  

2001 ◽  
Author(s):  
Karen E. Lunn ◽  
Alex Hartov ◽  
Francis E. Kennedy ◽  
Michael I. Miga ◽  
David W. Roberts ◽  
...  

2000 ◽  
Vol 3 (2) ◽  
pp. 129-146 ◽  
Author(s):  
MICHAEL I. MIGA ◽  
KEITH D. PAULSEN ◽  
FRANCIS E. KENNEDY ◽  
P. JACK HOOPES ◽  
ALEX HARTOV ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document