Accuracy of drug infusion pumps under computer control

S.B. Connor; T.J. Quill; J.R. Jacobs

doi:10.1109/10.256432

Draft for comment — Standards Australia drug infusion pumps — Committee HT/18-approval and test specification-medical electrical equipment Part 2: Specific requirements-drug infusion pumps & controllers

Confederation of Australian Critical Care Nurses Journal ◽

10.1016/s1033-3355(11)80047-0 ◽

1990 ◽

Vol 3 (4) ◽

pp. 13

Author(s):

David White

Keyword(s):

Electrical Equipment ◽

Drug Infusion ◽

Infusion Pumps ◽

Equipment Part ◽

Medical Electrical Equipment ◽

Test Specification

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Drug Infusion Pumps in Anesthesia, Critical Care, and Pain Management

The MGH Textbook of Anesthetic Equipment ◽

10.1016/b978-1-4377-0973-5.10017-9 ◽

2011 ◽

pp. 236-246 ◽

Cited By ~ 1

Author(s):

Nathaniel Sims ◽

M. Ellen Kinnealey ◽

Rick Hampton ◽

Gayle Fishman ◽

Harold DeMonaco

Keyword(s):

Critical Care ◽

Pain Management ◽

Drug Infusion ◽

Infusion Pumps

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Changeovers of vasoactive drug infusion pumps: impact of a quality improvement program

Critical Care ◽

10.1186/cc6209 ◽

2007 ◽

Vol 11 (6) ◽

pp. R133 ◽

Cited By ~ 22

Author(s):

Laurent Argaud ◽

Martin Cour ◽

Olivier Martin ◽

Marc Saint-Denis ◽

Tristan Ferry ◽

...

Keyword(s):

Quality Improvement ◽

Quality Improvement Program ◽

Vasoactive Drug ◽

Drug Infusion ◽

Improvement Program ◽

Infusion Pumps

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In vitro comparison of two changeover methods for vasoactive drug infusion pumps: quick-change versus automated relay

Biomedical Engineering / Biomedizinische Technik ◽

10.1515/bmt-2014-0140 ◽

2015 ◽

Vol 60 (4) ◽

Cited By ~ 2

Author(s):

Stéphanie Genay ◽

Bertrand Décaudin ◽

Sébastien Lédé ◽

Frédéric Feutry ◽

Christine Barthélémy ◽

...

Keyword(s):

Vasoactive Drug ◽

Drug Infusion ◽

Infusion Pumps ◽

In Vitro Comparison

AbstractThis study aimed to compare

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Development and in vitro evaluation of a flow-adjustable elastic drug infusion pump

Proceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in Medicine ◽

10.1177/0954411911419008 ◽

2011 ◽

Vol 225 (11) ◽

pp. 1070-1077 ◽

Cited By ~ 1

Author(s):

S-W Choi ◽

S-M Kang ◽

H-Y Kim ◽

K-W Nam

Keyword(s):

Flow Pattern ◽

Infusion Pump ◽

Injection Rate ◽

Chamber Pressure ◽

Elastic Membrane ◽

Physiological Status ◽

Drug Infusion ◽

Short Term ◽

Infusion Pumps

Passive-type drug infusion pumps have several advantages over active-type pumps including a simple drug chamber structure and relatively high operational stability. However, conventional passive-type infusion pumps also have several limitations compared to active ejection pumps, such as a fixed flowrate and monotonic flow pattern. To enhance the clinical feasibility of using passive-type drug infusion pumps, flow readjustment and flow regulation abilities are needed. This paper proposes a new portable elastic drug infusion pump that integrates the advantages of active and passive infusion pumps to improve clinical feasibility. The proposed infusion pump incorporates a passively driven drug chamber and an actively adjusted flow controller, which can adjust and regulate various target flowrates and adjust the flow pattern in accordance with the patient’s time-varying physiological status. The proposed infusion pump uses the contraction force of an expanded elastic membrane to extract the drug from the drug chamber for delivery into the patient’s body through an outlet catheter. It also utilizes a flow sensor, a flow resistor, and a motor-driven flow restrictor that can monitor the real-time flowrate through the outlet catheter and automatically regulate the actual flowrate around the target value. Experiments on the proposed system resulted in actual injection rates of 0.49 ± 0.03 (mean ± standard deviation), 0.98 ± 0.03, 1.49 ± 0.04, and 1.99 ± 0.03 ml/h when the target injection rate was set to 0.5, 1.0, 1.5, and 2.0 ml/h, respectively. During the entire period of operation from the fully filled state to the totally empty state, an inner-chamber pressure of >100 mmHg was maintained, which shows that the proposed infusion pump can stably maintain its target flowrate as the amount of drug remaining to be injected decreases. It appears that the proposed drug infusion pump can be applied to a wide variety of patient treatments that require short-term, accurate, and stable drug delivery.

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