Possible determinants of pulse-wave velocity in vivo

1988 ◽  
Vol 35 (5) ◽  
pp. 357-361 ◽  
Author(s):  
M. Okada
2017 ◽  
Author(s):  
Maria Zontak ◽  
Matthew Bruce ◽  
Michelle Hippke ◽  
Alan Schwartz ◽  
Matthew O'Donnell

2009 ◽  
Vol 61 (6) ◽  
pp. 1293-1299 ◽  
Author(s):  
Volker Herold ◽  
Marco Parczyk ◽  
Philipp Mörchel ◽  
Christian H. Ziener ◽  
Gert Klug ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Zhongshuai Teng ◽  
Feng Gao ◽  
Hua Xia ◽  
Wenliang Chen ◽  
Chenxi Li

Continuous monitoring of in vivo pulsatile blood flow and pulse wave velocity (PWV) is important for clinical applications. These parameters are correlated with physiological parameters, such as blood pressure and elasticity of blood vessels. A multimode fiber diffuse speckle contrast analysis (MMF-DSCA) system was developed for fast measurement of in vivo pulsatile blood flow and pulse wave velocity. With MMF and CCD sensor, the diffuse speckle could be captured and processed with higher temporal resolution of 3 ms. We also induced for the first time an MMF-DSCA for evaluation of PWV, which allows estimation of the blood pressure continuously. To validate its performance, both phantom and in vivo experiments were conducted. The results demonstrate that MMF-DSCA could achieve fast pulsatile blood flow measurement with detailed information of the pulse wave profile and velocity. Taking the advantages of being simple and cost-effective, the flexible system can be easily adapted for continuous monitoring of vital biosigns, such as heart rate, pulse wave, and blood pressure.


2016 ◽  
Vol 13 (C) ◽  
pp. 17 ◽  
Author(s):  
John Runciman ◽  
Martine McGregor ◽  
Gonçalo Silva ◽  
Gabrielle Monteith ◽  
Laurent Viel ◽  
...  

Ultrasonics ◽  
2015 ◽  
Vol 55 ◽  
pp. 92-103 ◽  
Author(s):  
Ryo Nagaoka ◽  
Genta Masuno ◽  
Kazuto Kobayashi ◽  
Shin Yoshizawa ◽  
Shin-ichiro Umemura ◽  
...  

2017 ◽  
Vol 12 (1) ◽  
Author(s):  
Marit H. N. van Velzen ◽  
Arjo J. Loeve ◽  
Egbert G. Mik ◽  
Sjoerd P. Niehof

The multiphotodiode array (MPA) is a novel transmission photoplethysmography (PPG) sensor to measure pulse wave velocity (PWV) in the finger. To validate the MPA, a setup was built to generate a red laser dot traveling over the MPA with known and constant scanning velocities. These scanning velocities were chosen to include speeds at least twice as high as those found in the normal range of PWV in healthy populations and were set at 12.9, 25.8, 36, or 46.7 m/s. The aim of this study was to verify the functionality of the MPA: performing local noninvasive PWV measurements. To illustrate the applicability of the MPA in clinical practice, an in vivo pilot study was conducted using the flow-mediated dilation (FMD) technique. The in vitro accuracy of the MPA was ±0.2%, 0.3%, 0.5%, and 0.6% at the applied scanning velocities. The MPA can measure PWVs with a maximum deviation of 3.0%. The in vivo pilot study showed a PWV before the FMD of 1.1±0.2 m/s. These results suggest that this novel MPA can reliably and accurately measure PWV within clinically relevant ranges and even well beyond.


2018 ◽  
Vol 314 (6) ◽  
pp. H1264-H1278 ◽  
Author(s):  
Junjing Su ◽  
Charmilie C. Logan ◽  
Alun D. Hughes ◽  
Kim H. Parker ◽  
Niti M. Dhutia ◽  
...  

Arterial stiffness and wave reflection are important components of the ventricular afterload. Therefore, we aimed to assess the arterial wave characteristics and mechanical properties of the proximal pulmonary arteries (PAs) in the hypoxic pulmonary hypertensive rat model. After 21 days in normoxic or hypoxic chambers (24 animals/group), animals underwent transthoracic echocardiography and PA catheterization with a dual-tipped pressure and Doppler flow sensor wire. Wave intensity analysis was performed. Artery rings obtained from the pulmonary trunk, right and left PAs, and aorta were subjected to a tensile test to rupture. Collagen and elastin content were determined. In hypoxic rats, proximal PA wall thickness, collagen content, tensile strength per unit collagen, maximal elastic modulus, and wall viscosity increased, whereas the elastin-to-collagen ratio and arterial distensibility decreased. Arterial pulse wave velocity was also increased, and the increase was more prominent in vivo than ex vivo. Wave intensity was similar in hypoxic and normoxic animals with negligible wave reflection. In contrast, the aortic maximal elastic modulus remained unchanged, whereas wall viscosity decreased. In conclusion, there was no evidence of altered arterial wave propagation in proximal PAs of hypoxic rats while the extracellular matrix protein composition was altered and collagen tensile strength increased. This was accompanied by altered mechanical properties in vivo and ex vivo. NEW & NOTEWORTHY In rats exposed to chronic hypoxia, we have shown that pulse wave velocity in the proximal pulmonary arteries increased and pressure dependence of the pulse wave velocity was steeper in vivo than ex vivo leading to a more prominent increase in vivo.


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