scholarly journals Block of ATP-Binding Cassette B19 Ion Channel Activity by 5-Nitro-2-(3-Phenylpropylamino)-Benzoic Acid Impairs Polar Auxin Transport and Root Gravitropism

2014 ◽  
Vol 166 (4) ◽  
pp. 2091-2099 ◽  
Author(s):  
M. Cho ◽  
E. M. Henry ◽  
D. R. Lewis ◽  
G. Wu ◽  
G. K. Muday ◽  
...  
Keyword(s):  
Benzoic Acid ◽  
Ion Channel ◽  
Auxin Transport ◽  
Polar Auxin Transport ◽  
Atp Binding ◽  
Channel Activity ◽  
Root Gravitropism ◽  
Atp Binding Cassette

scholarly journals LAZY3 plays a pivotal role in positive root gravitropism in Lotus japonicus

2019 ◽  
Vol 71 (1) ◽  
pp. 168-177 ◽  
Author(s):  
Yaping Chen ◽  
Shaoming Xu ◽  
Lu Tian ◽  
Leru Liu ◽  
Mingchao Huang ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Auxin Transport ◽  
Positive Root ◽  
Lotus Japonicus ◽  
Polar Auxin Transport ◽  
Pivotal Role ◽  
Root Gravitropism ◽  
Root Stele

LAZY3, polarly localized to the plasma membrane in root stele cells, is involved in rootward polar auxin transport in roots and required for positive root gravitropism in Lotus japonicus.

scholarly journals SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator

2008 ◽  
Vol 364 (1514) ◽  
pp. 257-267 ◽  
Author(s):  
Jussi Aittoniemi ◽  
Constantina Fotinou ◽  
Tim J Craig ◽  
Heidi de Wet ◽  
Peter Proks ◽  
...  
Keyword(s):  
Ion Channel ◽  
Metabolic Regulation ◽  
Molecular Mechanisms ◽  
Neonatal Diabetes ◽  
Regulatory Subunit ◽  
Atp Binding ◽  
Congenital Hyperinsulinism ◽  
Loss Of Function ◽  
Open Probability ◽  
Atp Binding Cassette

SUR1 is an ATP-binding cassette (ABC) transporter with a novel function. In contrast to other ABC proteins, it serves as the regulatory subunit of an ion channel. The ATP-sensitive (K ATP ) channel is an octameric complex of four pore-forming Kir6.2 subunits and four regulatory SUR1 subunits, and it links cell metabolism to electrical activity in many cell types. ATPase activity at the nucleotide-binding domains of SUR results in an increase in K ATP channel open probability. Conversely, ATP binding to Kir6.2 closes the channel. Metabolic regulation is achieved by the balance between these two opposing effects. Precisely how SUR1 talks to Kir6.2 remains unclear, but recent studies have identified some residues and domains that are involved in both physical and functional interactions between the two proteins. The importance of these interactions is exemplified by the fact that impaired regulation of Kir6.2 by SUR1 results in human disease, with loss-of-function SUR1 mutations causing congenital hyperinsulinism and gain-of-function SUR1 mutations leading to neonatal diabetes. This paper reviews recent data on the regulation of Kir6.2 by SUR1 and considers the molecular mechanisms by which SUR1 mutations produce disease.

scholarly journals Extracellular ATP Inhibits Root Gravitropism at Concentrations That Inhibit Polar Auxin Transport

2003 ◽  
Vol 131 (1) ◽  
pp. 147-154 ◽  
Author(s):  
Wenqiang Tang ◽  
Shari R. Brady ◽  
Yu Sun ◽  
Gloria K. Muday ◽  
Stanley J. Roux
Keyword(s):  
Auxin Transport ◽  
Extracellular Atp ◽  
Polar Auxin Transport ◽  
Root Gravitropism

scholarly journals The role of Arabidopsis Actin-Related Protein 3 in amyloplast sedimentation and polar auxin transport in root gravitropism

2016 ◽  
Vol 67 (18) ◽  
pp. 5325-5337 ◽  
Author(s):  
Jun-Jie Zou ◽  
Zhong-Yu Zheng ◽  
Shan Xue ◽  
Han-Hai Li ◽  
Yu-Ren Wang ◽  
...  
Keyword(s):  
Auxin Transport ◽  
Polar Auxin Transport ◽  
Related Protein ◽  
Root Gravitropism

scholarly journals Regulation von ABC-Transportern durch FKBPs

BIOspektrum ◽  
2021 ◽  
Vol 27 (2) ◽  
pp. 131-134
Author(s):  
Markus Geisler
Keyword(s):  
Abc Transporter ◽  
Abc Transporters ◽  
Plant Hormone ◽  
Auxin Transport ◽  
Current Knowledge ◽  
Binding Protein ◽  
Atp Binding ◽  
Fk506 Binding Protein ◽  
Atp Binding Cassette

AbstractThe plant hormone auxin is distributed in the plant by a sophisticated network of importers and exporters, including members of the ABCB subclass of ATP-binding cassette (ABC) transporters. ABCB-mediated auxin transport is controlled by Twisted Dwarf1, a member of the FK506-binding protein (FKBP) family. Here, we summarize current knowledge on ABC transporter regulation by FKBPs, which seems to be conserved over kingdoms and ABC subfamilies arguing for conserved mechanism of plant and mammalian post-translational transporter regulation.

Auxin Transport Inhibitors. II. 2-(1-Pyrenol)Benzoic Acid, a Potent Inhibitor of Polar Auxin Transport

1977 ◽  
Vol 4 (3) ◽  
pp. 321 ◽  
Author(s):  
GF Katekar ◽  
AE Geissler
Keyword(s):  
Benzoic Acid ◽  
Auxin Transport ◽  
Indoleacetic Acid ◽  
Potent Inhibitor ◽  
Polar Auxin Transport ◽  
Active Inhibitor ◽  
Polar Transport ◽  
Highly Active ◽  
Transport Inhibitors ◽  
Auxin Transport Inhibitors

2-(1-Pyrenoyl)benzoic acid is shown to be a highly active inhibitor of auxin transport by its ability to prevent the polar transport of indoleacetic acid in bean petioles. It is comparable in activity to other known auxin transport inhibitors, and also affects apical dominance and the geotropic and phototropic responses.

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