scholarly journals Making Sense of Senescence (Molecular Genetic Regulation and Manipulation of Leaf Senescence)

1997 ◽  
Vol 113 (2) ◽  
pp. 313-319 ◽  
Author(s):  
S. Gan ◽  
R. M. Amasino
2004 ◽  
Vol 18 (5) ◽  
pp. 705-709 ◽  
Author(s):  
Lin Lin ◽  
David Hicks ◽  
Bo Xu ◽  
Jessica E Sigel ◽  
Wilma F Bergfeld ◽  
...  

2020 ◽  
Vol 25 (10) ◽  
pp. 3933
Author(s):  
T. B. Pecherina ◽  
A. G. Kutikhin

Currently, the development of chronic heart failure (CHF) is considered from the perspective of pathological structural remodeling of myocardium and fibrosis. Despite the widespread use of molecular genetic markers in clinical practice, only a small number of them are used to evaluate remodeling processes, as well as to predict potential complications associated with heart failure (HF). In addition, the relationship between many biomarkers with instrumental and histological confirmation of myocardial fibrosis has not yet been determined. Myocardial fibrosis remains quite debatable and controversial subject, which actualizes the further study of this direction. The discovery of pathogenetic and diagnostic markers of myocardial fibrosis could contribute to the development of targeted therapy. Of particular interest is the search for possible pathogenetic markers, since this is relevant for clinical practice.


2016 ◽  
Vol 30 (1) ◽  
pp. 77-91 ◽  
Author(s):  
Ryan K. Mitchell ◽  
Ming Hu ◽  
Pauline L. Chabosseau ◽  
Matthew C. Cane ◽  
Gargi Meur ◽  
...  

2020 ◽  
Vol 1 (1) ◽  
pp. 01-07
Author(s):  
George Zhu

Anemia is clinical common event. In this study,a retrospective study of 36 different types of anemias was place in proper interpretative review for their therapeutical outcome. By using comprehensive treatment regimen according to patients’ condition, 23 patients obtained cure or complete remission (CR), with the exception of refractory cancers and uremic anemia. Iron supplement was provided in 5 iron deficiency anemia. One megaloblastic anemia required the prescription of the supplement of vitamin B12 or folate deficiency. 2 aplastic anemia obtained complete remission with the integrated protocol of methyltestosterone,adenine,leucogen,and levamisol. Steroid hormone (e.g. prednisone) mixed traditional medicine were occasionally promising benefit in a nephrotic syndrome and renal insufficiency. Among 2 cases with dug- induced immune hemolytic anemia (DIIHA), laboratory studies a patient's serum contained paracetamol -dependent antibody that in the presence of paracetamol, agglutinated in vitro with "O" red cells with or without complement. Drug antibody titer was 1:4 positive. The reactive mechanism was attributed to both immune complex type and drug-adsorption, whereas another herba origanum vulgare- induced hemolysis secondary to drug adsorption only. In addition, regarding anemia caused by malignant tumours, the molecular genetic regulation of retinoic acid in acute promyelocytic leukemia (APL) has been further illustrated(see figure in full text). Therefore,to strengthen the active prevention and/or early interceptive treatment of anemia is our care.


2000 ◽  
Vol 28 (5) ◽  
pp. A243-A243
Author(s):  
G. R. Teakle ◽  
E. P. Kop ◽  
L. B. Smith ◽  
C. D. Ryder ◽  
E. R. McClenaghan ◽  
...  

1992 ◽  
pp. 149-165
Author(s):  
Alan B. Bennett ◽  
Ellen M. Klann ◽  
Coralie C. Lashbrook ◽  
Serge Yelle ◽  
Roger T. Chetelat ◽  
...  

2008 ◽  
Vol 363 (1496) ◽  
pp. 1569-1578 ◽  
Author(s):  
Christopher J Lowe

Progress in developmental biology, phylogenomics and palaeontology over the past five years are all making major contributions to a long-enduring problem in comparative biology: the early origins of the deuterostome phyla. Recent advances in the developmental biology of hemichordates have given a unique insight into developmental similarities between this phylum and chordates. Transcriptional and signalling gene expression patterns between the two groups during the early development of the anteroposterior and dorsoventral axes reveal close similarities, despite large morphological disparity between the body plans. These genetic networks have been proposed to play conserved roles in patterning centralized nervous systems in metazoans, yet seem to play a conserved role in patterning the diffusely organized basiepithelial nerve net of the hemichordates. Developmental genetic data are providing a unique insight into early deuterostome evolution, revealing a complexity of genetic regulation previously attributed only to vertebrates. While these data allow for key insights into the development of early deuterostomes, their utility for reconstructing ancestral morphologies is less certain, and morphological, palaeontological and molecular datasets should all be considered carefully when speculating about ancestral deuterostome features.


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