scholarly journals From genome to "venome": Molecular origin and evolution of the snake venom proteome inferred from phylogenetic analysis of toxin sequences and related body proteins

2005 ◽  
Vol 15 (3) ◽  
pp. 403-420 ◽  
Author(s):  
B. G. Fry
2016 ◽  
Vol 84 (1) ◽  
pp. 8-11 ◽  
Author(s):  
Jordan Debono ◽  
Bing Xie ◽  
Aude Violette ◽  
Rudy Fourmy ◽  
Marc Jaeger ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Kuan Hu ◽  
Yiming Tao ◽  
Juanni Li ◽  
Zhuang Liu ◽  
Xinyan Zhu ◽  
...  

CCN gene family members have recently been identified as multifunctional regulators involved in diverse biological functions, especially in vascular and skeletal development. In the present study, a comparative genomic and phylogenetic analysis was performed to show the similarities and differences in structure and function of CCNs from different organisms and to reveal their potential evolutionary relationship. First, CCN homologs of metazoans from different species were identified. Then we made multiple sequence alignments, MEME analysis, and functional sites prediction, which show the highly conserved structural features among CCN metazoans. The phylogenetic tree was further established, and thus CCNs were found undergoing extensive lineage-specific duplication events and lineage-specific expansion during the evolutionary process. Besides, comparative analysis about the genomic organization and chromosomal CCN gene surrounding indicated a clear orthologous relationship among these species counterparts. At last, based on these research results above, a potential evolutionary scenario was generated to overview the origin and evolution of the CCN gene family.


Genome ◽  
2013 ◽  
Vol 56 (4) ◽  
pp. 233-237
Author(s):  
Leilei Zhan ◽  
Chao Jiang

Mutually exclusive splicing, one type of alternative splicing, involves selection of alternatively spliced exons arranged in tandem and creates protein products with substitution of one segment of the amino acid sequence for another. Previous studies revealed that exon 5 of 14-3-3ξ from Apis mellifera (western honeybee) had three mutually exclusive exons, while orthologous exon of Nasonia vitripennis (parasitic wasp) had only two, suggesting that cases of exon gain or loss might have happened during the evolution of hymenopteran species. In the current study, we annotated and analyzed the 14-3-3ξ genes from 20 hymenopteran species successfully, and the results of phylogenetic analysis revealed the presence of a new mutually exclusive exon in corbiculate bees. In addition, we found that duplication via staggered homologous recombination was responsible for the origin of the new exon.


2007 ◽  
Vol 26 (1) ◽  
pp. 69-85 ◽  
Author(s):  
Maurício V. Mazzi ◽  
Angelo J. Magro ◽  
Saulo F. Amui ◽  
Clayton Z. Oliveira ◽  
Fábio K. Ticli ◽  
...  

Evolution ◽  
2015 ◽  
Vol 69 (11) ◽  
pp. 2995-3003 ◽  
Author(s):  
Constanze Bickelmann ◽  
James M. Morrow ◽  
Jing Du ◽  
Ryan K. Schott ◽  
Ilke van Hazel ◽  
...  

1989 ◽  
Vol 63 (5) ◽  
pp. 677-690 ◽  
Author(s):  
Fernando E. Novas

The tarsus and distal end of the tibia are described in Herrerasauridae, a family that includes the oldest known dinosaurs. This tarsal configuration is compared to those of more advanced dinosaurs and to other archosaurs. Through phylogenetic analysis of the morphological characters, a picture emerges of the evolutionary changes in the ankles of early dinosaurs.The tibia of the herrerasaurids has a quadrangular distal articular surface, with a shallow ventrolateral notch. This morphology is strikingly similar to that of the lagosuchid thecodontsPseudolagosuchusandLagosuchusand represents the most primitive tibial condition known for Dinosauria.Aside from the derived states possessed by Theropoda, Sauropodomorpha, and Ornithischia, respectively, it was impossible to recognize synapomorphies in tibiotarsal anatomy shared by these groups exclusive of Herrerasauridae. The transverse broadening of the distal end of the tibia seems to have been attained independently by ornithischians, theropods, and sauropodomorphs.The tarsus of herrerasaurids is characterized by an astragalus with a small but conspicuous lateroventral depression, by a pyramidal calcaneum with a ventromedial projection that articulates into the cavity of the astragalus just mentioned, and by a posterolaterally directed calcaneal tuber. These characters are also seen inLagosuchus(a close relative of dinosaurs), in the prosauropodRiojasaurusand, insofar as the astragalus is concerned, in the primitive dinosaurWalkeria, which suggests that dinosaurs of different lineages shared the same tarsal condition.By definition, this type of articulation between the astragalus and calcaneum follows the “crocodile-reversed” tarsal condition, suggesting that the tarsus in lagosuchids and dinosaurs could be derived from the “crocodile-reversed” pattern present in Ornithosuchidae andEuparkeria. In contrast, the mesotarsal ankle of lagosuchids and dinosaurs lacks the synapomorphies of the “crocodile-normal” ankle present in Crocodylia, Rauisuchidae, Aetosauria, and other archosaurs.It is concluded that Herrerasauridae retained the primitive tibiotarsal condition for Dinosauria, from which those of the Ornithischia, Sauropodomorpha, and Theropoda were derived. Furthermore, tibiotarsal anatomy supports monophyly of Dinosauria.


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