scholarly journals A structure-based deep learning framework for protein engineering

2019 ◽  
Author(s):  
Raghav Shroff ◽  
Austin W. Cole ◽  
Barrett R. Morrow ◽  
Daniel J. Diaz ◽  
Isaac Donnell ◽  
...  
Keyword(s):  
Neural Network ◽  
Amino Acids ◽  
Deep Learning ◽  
Protein Engineering ◽  
Convolutional Neural Network ◽  
State Of The Art ◽  
A Priori ◽  
Novel Proteins ◽  
Learning Framework

AbstractWhile deep learning methods exist to guide protein optimization, examples of novel proteins generated with these techniques require a priori mutational data. Here we report a 3D convolutional neural network that associates amino acids with neighboring chemical microenvironments at state-of-the-art accuracy. This algorithm enables identification of novel gain-of-function mutations, and subsequent experiments confirm substantive phenotypic improvements in stability-associated phenotypes in vivo across three diverse proteins.

scholarly journals Identifying Ethnics of People through Face Recognition: A Deep CNN Approach

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Ahmed Jawad A. AlBdairi ◽  
Zhu Xiao ◽  
Mohammed Alghaili
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Face Recognition ◽  
Convolutional Neural Network ◽  
State Of The Art ◽  
Research Community ◽  
Facial Features ◽  
New Model ◽  
Image Dataset ◽  
Deep Cnn

The interest in face recognition studies has grown rapidly in the last decade. One of the most important problems in face recognition is the identification of ethnics of people. In this study, a new deep learning convolutional neural network is designed to create a new model that can recognize the ethnics of people through their facial features. The new dataset for ethnics of people consists of 3141 images collected from three different nationalities. To the best of our knowledge, this is the first image dataset collected for the ethnics of people and that dataset will be available for the research community. The new model was compared with two state-of-the-art models, VGG and Inception V3, and the validation accuracy was calculated for each convolutional neural network. The generated models have been tested through several images of people, and the results show that the best performance was achieved by our model with a verification accuracy of 96.9%.

scholarly journals Liver Cancer Detection Using Hybridized Fully Convolutional Neural Network Based on Deep Learning Framework

IEEE Access ◽  
2020 ◽  
Vol 8 ◽  
pp. 129889-129898
Author(s):  
Xin Dong ◽  
Yizhao Zhou ◽  
Lantian Wang ◽  
Jingfeng Peng ◽  
Yanbo Lou ◽  
...  
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Liver Cancer ◽  
Convolutional Neural Network ◽  
Cancer Detection ◽  
Learning Framework

scholarly journals Investigation of optimal configurations of a convolutional neural network for the identification of objects in real-time

2019 ◽  
pp. 417-423
Author(s):  
M A Isayev ◽  
D A Savelyev
Keyword(s):  
Neural Network ◽  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Network ◽  
Real Time ◽  
State Of The Art ◽  
Average Precision ◽  
The Core ◽  
Particular Solution ◽  
Optimal Configurations

The comparison of different convolutional neural networks which are the core of the most actual solutions in the computer vision area is considers in hhe paper. The study includes benchmarks of this state-of-the-art solutions by some criteria, such as mAP (mean average precision), FPS (frames per seconds), for the possibility of real-time usability. It is concluded on the best convolutional neural network model and deep learning methods that were used at particular solution.

scholarly journals Segmentation of Overlapping Cervical Cells with Mask Region Convolutional Neural Network

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Jiajia Chen ◽  
Baocan Zhang
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Convolutional Neural Network ◽  
State Of The Art ◽  
Cytological Analysis ◽  
Segmentation Method ◽  
Challenging Tasks ◽  
Diagnostic Technology ◽  
Cervical Cells ◽  
Bounding Boxes

The task of segmenting cytoplasm in cytology images is one of the most challenging tasks in cervix cytological analysis due to the presence of fuzzy and highly overlapping cells. Deep learning-based diagnostic technology has proven to be effective in segmenting complex medical images. We present a two-stage framework based on Mask RCNN to automatically segment overlapping cells. In stage one, candidate cytoplasm bounding boxes are proposed. In stage two, pixel-to-pixel alignment is used to refine the boundary and category classification is also presented. The performance of the proposed method is evaluated on publicly available datasets from ISBI 2014 and 2015. The experimental results demonstrate that our method outperforms other state-of-the-art approaches with DSC 0.92 and FPRp 0.0008 at the DSC threshold of 0.8. Those results indicate that our Mask RCNN-based segmentation method could be effective in cytological analysis.

Unsupervised Representation High-Resolution Remote Sensing Image Scene Classification via Contrastive Learning Convolutional Neural Network

2021 ◽  
Vol 87 (8) ◽  
pp. 577-591
Author(s):  
Fengpeng Li ◽  
Jiabao Li ◽  
Wei Han ◽  
Ruyi Feng ◽  
Lizhe Wang
Keyword(s):  
Neural Network ◽  
Remote Sensing ◽  
Deep Learning ◽  
High Resolution ◽  
Convolutional Neural Network ◽  
State Of The Art ◽  
Remote Sensing Image ◽  
Scene Classification ◽  
Data Set ◽  
Unsupervised Deep Learning

Inspired by the outstanding achievement of deep learning, supervised deep learning representation methods for high-spatial-resolution remote sensing image scene classification obtained state-of-the-art performance. However, supervised deep learning representation methods need a considerable amount of labeled data to capture class-specific features, limiting the application of deep learning-based methods while there are a few labeled training samples. An unsupervised deep learning representation, high-resolution remote sensing image scene classification method is proposed in this work to address this issue. The proposed method, called contrastive learning, narrows the distance between positive views: color channels belonging to the same images widens the gaps between negative view pairs consisting of color channels from different images to obtain class-specific data representations of the input data without any supervised information. The classifier uses extracted features by the convolutional neural network (CNN)-based feature extractor with labeled information of training data to set space of each category and then, using linear regression, makes predictions in the testing procedure. Comparing with existing unsupervised deep learning representation high-resolution remote sensing image scene classification methods, contrastive learning CNN achieves state-of-the-art performance on three different scale benchmark data sets: small scale RSSCN7 data set, midscale aerial image data set, and large-scale NWPU-RESISC45 data set.

scholarly journals Global and Local Attention-Based Free-Form Image Inpainting

Sensors ◽  
2020 ◽  
Vol 20 (11) ◽  
pp. 3204
Author(s):  
S. M. Nadim Uddin ◽  
Yong Ju Jung
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Convolutional Neural Network ◽  
State Of The Art ◽  
Image Inpainting ◽  
Experimental Results ◽  
Free Form ◽  
Local Similarity ◽  
Global And Local ◽  
Similarity Information

Deep-learning-based image inpainting methods have shown significant promise in both rectangular and irregular holes. However, the inpainting of irregular holes presents numerous challenges owing to uncertainties in their shapes and locations. When depending solely on convolutional neural network (CNN) or adversarial supervision, plausible inpainting results cannot be guaranteed because irregular holes need attention-based guidance for retrieving information for content generation. In this paper, we propose two new attention mechanisms, namely a mask pruning-based global attention module and a global and local attention module to obtain global dependency information and the local similarity information among the features for refined results. The proposed method is evaluated using state-of-the-art methods, and the experimental results show that our method outperforms the existing methods in both quantitative and qualitative measures.

scholarly journals Image Steganalysis via Diverse Filters and Squeeze-and-Excitation Convolutional Neural Network

Mathematics ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 189
Author(s):  
Feng Liu ◽  
Xuan Zhou ◽  
Xuehu Yan ◽  
Yuliang Lu ◽  
Shudong Wang
Keyword(s):  
Neural Network ◽  
Neural Networks ◽  
Deep Learning ◽  
Convolutional Neural Network ◽  
Convolutional Neural Networks ◽  
State Of The Art ◽  
Image Steganalysis ◽  
Process Information ◽  
Effective Network ◽  
Convolution Filters

Steganalysis is a method to detect whether the objects contain secret messages. With the popularity of deep learning, using convolutional neural networks (CNNs), steganalytic schemes have become the chief method of combating steganography in recent years. However, the diversity of filters has not been fully utilized in the current research. This paper constructs a new effective network with diverse filter modules (DFMs) and squeeze-and-excitation modules (SEMs), which can better capture the embedding artifacts. As the essential parts, combining three different scale convolution filters, DFMs can process information diversely, and the SEMs can enhance the effective channels out from DFMs. The experiments presented that our CNN is effective against content-adaptive steganographic schemes with different payloads, such as S-UNIWARD and WOW algorithms. Moreover, some state-of-the-art methods are compared with our approach to demonstrate the outstanding performance.

scholarly journals Automated Fruit Classification Using Deep Convolutional Neural Network

2020 ◽  
Vol 3 (2) ◽  
pp. 177-178
Author(s):  
John Jowil D. Orquia ◽  
El Jireh Bibangco
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Convolutional Neural Network ◽  
New Technologies ◽  
Learning Algorithm ◽  
State Of The Art ◽  
Complex Model ◽  
Deep Convolutional Neural Network ◽  
Machine Learning Algorithm ◽  
Learning Models

Manual Fruit classification is the traditional way of classifying fruits. It is manual contact-labor that is time-consuming and often results in lesser productivity, inconsistency, and sometimes damaging the fruits (Prabha & Kumar, 2012). Thus, new technologies such as deep learning paved the way for a faster and more efficient method of fruit classification (Faridi & Aboonajmi, 2017). A deep convolutional neural network, or deep learning, is a machine learning algorithm that contains several layers of neural networks stacked together to create a more complex model capable of solving complex problems. The utilization of state-of-the-art pre-trained deep learning models such as AlexNet, GoogLeNet, and ResNet-50 was widely used. However, such models were not explicitly trained for fruit classification (Dyrmann, Karstoft, & Midtiby, 2016). The study aimed to create a new deep convolutional neural network and compared its performance to fine-tuned models based on accuracy, precision, sensitivity, and specificity.

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