scholarly journals Potential antigenic mismatch of the H3N2 component of the 2019 Southern Hemisphere influenza vaccine

2019 ◽  
Author(s):  
Sigrid Gouma ◽  
Madison Weirick ◽  
Scott E. Hensley

AbstractHere, we find that the egg-adapted H3N2 component of the 2019 Southern Hemisphere influenza vaccine elicits an antibody response in ferrets that is highly focused on antigenic site A of hemagglutinin. This is potentially problematic since most H3N2 viruses currently circulating in the Southern Hemisphere possess antigenic site A substitutions.

2019 ◽  
Vol 70 (11) ◽  
pp. 2432-2434 ◽  
Author(s):  
Sigrid Gouma ◽  
Madison Weirick ◽  
Scott E Hensley

Abstract Here, we find that the egg-adapted H3N2 component of the 2019 Southern Hemisphere influenza vaccine elicits an antibody response in ferrets that is highly focused on antigenic site A of hemagglutinin. This is potentially problematic as most H3N2 viruses currently circulating in the Southern Hemisphere possess antigenic site A substitutions.


Vaccine ◽  
2012 ◽  
Vol 30 (2) ◽  
pp. 436-441 ◽  
Author(s):  
Ema Sacadura-Leite ◽  
Antonio Sousa-Uva ◽  
Helena Rebelo-de-Andrade

Vaccine ◽  
2020 ◽  
Vol 38 (33) ◽  
pp. 5171-5177
Author(s):  
Krissy K. Moehling ◽  
Richard K. Zimmerman ◽  
Mary Patricia Nowalk ◽  
Chyongchiou Jeng Lin ◽  
Judith M. Martin ◽  
...  

2008 ◽  
Vol 2 (3) ◽  
pp. 93-98
Author(s):  
Christopher Burrell ◽  
Robert Booy ◽  
Nicholas Wood ◽  
Anne-Marie Egan ◽  
David Taverner ◽  
...  

2021 ◽  
Author(s):  
Gratis Research

Intranasal vaccine is a novel candidate that could improve the current injectable vaccine for the to prevent seasonal influenza epidemics. Influenza intranasal spray vaccine causes a local antibody response.


PEDIATRICS ◽  
2021 ◽  
pp. e2020019901
Author(s):  
Danielle J. Wall ◽  
Manish M. Patel ◽  
Jessie R. Chung ◽  
Benjamin Lee ◽  
Fatimah S. Dawood

1979 ◽  
Vol 10 (2) ◽  
pp. 184-187 ◽  
Author(s):  
D L Murray ◽  
D T Imagawa ◽  
D M Okada ◽  
J W St Geme

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