scholarly journals Terasaki Spiral Ramps and Intracellular Diffusion

2019 ◽  
Author(s):  
Greg Huber ◽  
Michael Wilkinson
Keyword(s):  
Endoplasmic Reticulum ◽  
Water Soluble ◽  
Eukaryotic Cells ◽  
Bilayer Membranes ◽  
Highly Efficient ◽  
Intracellular Diffusion ◽  
Efficient Transport

AbstractThe sheet-like endoplasmic reticulum (ER) of eukaryotic cells has been found to be riddled with spiral dislocations, known as ‘Terasaki ramps’, in the vicinity of which the doubled bilayer membranes which make up ER sheets can be approximately modeled by helicoids. Here we analyze diffusion on a surface with locally helicoidal topological dislocations, and use the results to argue that the Terasaki ramps facilitate a highly efficient transport of water-soluble molecules within the lumen of the endoplasmic reticulum.

Oxonol dyes

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Heinz Mustroph
Keyword(s):  
Silver Halide ◽  
Medical Diagnostics ◽  
Water Soluble ◽  
Eukaryotic Cells ◽  
Polymethine Dyes ◽  
Technical Application ◽  
Structural Types ◽  
Oxonol Dyes ◽  
Oxygen Atoms

Abstract Oxonol dyes are classified as anionic polymethine dyes, which cover a wide variety of structural types. The name of the class originates from the oxygen atoms which terminate each end of the polymethine chains that form the backbone of their structure. In technically useful dyes, these oxygen atoms tend to be substituents of heterocycles. The main technical application of water soluble oxonol dyes was in silver halide photography as filter dyes and antihalation dyes. Lipophilic oxonol dyes are used in bio-analysis and medical diagnostics to stain cells, bacteria or liposomes for example. Their main bioanalytical usage is in the determination of membrane potentials in eukaryotic cells and prokaryotic bacteria.

Highly efficient water-soluble visible light photoinitiators

2015 ◽  
Vol 54 (4) ◽  
pp. 473-479 ◽  
Author(s):  
Stephan Benedikt ◽  
Jieping Wang ◽  
Marica Markovic ◽  
Norbert Moszner ◽  
Kurt Dietliker ◽  
...  
Keyword(s):  
Visible Light ◽  
Water Soluble ◽  
Highly Efficient

Intramembrane proteolysis and post-targeting functions of signal peptides

2003 ◽  
Vol 31 (6) ◽  
pp. 1243-1247 ◽  
Author(s):  
B. Martoglio
Keyword(s):  
Endoplasmic Reticulum ◽  
Lipid Bilayer ◽  
Signal Peptide ◽  
Eukaryotic Cells ◽  
Endoplasmic Reticulum Membrane ◽  
Signal Peptides ◽  
Peptide Fragments ◽  
Intramembrane Proteolysis ◽  
Signal Sequences ◽  
Membrane Spanning

Signal sequences are the addresses of proteins destined for secretion. In eukaryotic cells, they mediate targeting to the endoplasmic reticulum membrane and insertion into the translocon. Thereafter, signal sequences are cleaved from the pre-protein and liberated into the endoplasmic reticulum membrane. We have recently reported that some liberated signal peptides are further processed by the intramembrane-cleaving aspartic protease signal peptide peptidase. Cleavage in the membrane-spanning portion of the signal peptide promotes the release of signal peptide fragments from the lipid bilayer. Typical processes that include intramembrane proteolysis is the regulatory or signalling function of cleavage products. Likewise, signal peptide fragments liberated upon intramembrane cleavage may promote such post-targeting functions in the cell.

Highly Efficient, Water-Soluble Polarizing Agents for Dynamic Nuclear Polarization at High Frequency

2013 ◽  
Vol 125 (41) ◽  
pp. 11058-11061 ◽  
Author(s):  
Claire Sauvée ◽  
Melanie Rosay ◽  
Gilles Casano ◽  
Fabien Aussenac ◽  
Ralph T. Weber ◽  
...  
Keyword(s):  
Dynamic Nuclear Polarization ◽  
High Frequency ◽  
Nuclear Polarization ◽  
Water Soluble ◽  
Highly Efficient
Sign in / Sign up

Export Citation Format

Share Document