scholarly journals Complete genome of a Measles virus from Roraima state, Brazil

2018 ◽  
Author(s):  
Cátia Alexandra Ribeiro Meneses ◽  
Valdinete Alves do Nascimento ◽  
Victor Costa de Souza ◽  
Rodrigo Melo Maito ◽  
Marconi Aragão Gomes ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Latin America ◽  
Genome Sequencing ◽  
Complete Genome ◽  
Measles Virus ◽  
Current Knowledge ◽  
Wild Type ◽  
The Usa ◽  
Global Concern ◽  
Human Infectious Disease

SUMMARYMeasles is a human infectious disease of global concern caused by the measles virus. In this study, we report the complete genome sequencing of one measles isolate, genotype D8, obtained in Boa Vista city, the capital of the Roraima State, Brazil, directly from the urine sample. Phylogenetics reconstruction grouped the genome described in this study with samples from Australia, Italy, United Kingdom, and the USA. To our knowledge, this is the first complete genome of a wild-type measles virus from Latin America. Therefore, the present data strengthens the current knowledge about the molecular epidemiology of measles worldwide.SponsorshipsCNPq / CAPES / MS-DECIT / Fiocruz

scholarly journals Complete Genome Sequences of Six Measles Virus Strains

2018 ◽  
Vol 6 (13) ◽  
Author(s):  
My V. T. Phan ◽  
Claudia M. E. Schapendonk ◽  
Bas B. Oude Munnink ◽  
Marion P. G. Koopmans ◽  
Rik L. de Swart ◽  
...  
Keyword(s):  
Next Generation Sequencing ◽  
Complete Genome ◽  
Measles Virus ◽  
Genetic Characterization ◽  
Critical Component ◽  
Wild Type ◽  
Genome Sequences ◽  
Virus Strains ◽  
Generation Sequencing

ABSTRACT Genetic characterization of wild-type measles virus (MV) strains is a critical component of measles surveillance and molecular epidemiology. We have obtained complete genome sequences of six MV strains belonging to different genotypes, using random-primed next generation sequencing.

scholarly journals Complete Genome Sequencing of 10 Brucella abortus Biovar 3 Strains Isolated from Water Buffalo

2018 ◽  
Vol 6 (16) ◽  
pp. e00180-18 ◽  
Author(s):  
Rubina Paradiso ◽  
Massimiliano Orsini ◽  
Daniela Criscuolo ◽  
Rosanna Borrelli ◽  
Ornella Valvini ◽  
...  
Keyword(s):  
Latin America ◽  
Central Asia ◽  
Genome Sequencing ◽  
Genome Assembly ◽  
Brucella Abortus ◽  
Complete Genome ◽  
Water Buffalo ◽  
Mediterranean Area ◽  
Campania Region ◽  
Content Type

ABSTRACT Brucellosis is a zoonotic disease that affects both humans and animals. Its distribution is global, concentrated in the Mediterranean area, India, Central Asia, and Latin America. Here, we present a complete genome assembly of 10 Brucella abortus strains isolated from water buffaloes farmed in the Campania region of Italy.

scholarly journals Complete Genome Sequences of Measles Virus Genotype D8 Isolates from South Korea in 2016

2019 ◽  
Vol 8 (29) ◽  
Author(s):  
You-Jin Kim ◽  
Hae Ji Kang ◽  
Su-Jin Kim ◽  
Hye Min Lee ◽  
Sung Soon Kim
Keyword(s):  
Genetic Diversity ◽  
South Korea ◽  
Complete Genome ◽  
Measles Virus ◽  
Virus Transmission ◽  
Wild Type ◽  
Genome Sequences ◽  
Virus Genotype

The complete genome sequences of three wild-type measles viruses (genotype D8) isolated from patients in South Korea were determined. These are the first reported complete genome sequences of measles viruses obtained from South Korea, and the availability of these sequences will improve our understanding of measles virus transmission and genetic diversity.

scholarly journals Whole-Genome Sequencing of an Unusual Human Papillomavirus (HPV71) from Latin America (Brazil)

2020 ◽  
Vol 9 (24) ◽  
Author(s):  
Edivaldo Costa Sousa Junior ◽  
Allan Kaio Silva ◽  
Laryssa Danielle da Silva Reis ◽  
Lana Patricia da Silva Fonseca ◽  
Fabiano Reis da Silva ◽  
...  
Keyword(s):  
Latin America ◽  
Human Papillomavirus ◽  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Complete Genome ◽  
Whole Genome ◽  
Complete Genome Sequencing

ABSTRACT We report the complete genome sequencing of human papillomavirus 71 from Latin America (Brazil).

scholarly journals Complete Genome Sequence of a Wild-Type Measles Virus Isolated during a 2016 Winter Outbreak in a Refugee Settlement in Calais, France

2017 ◽  
Vol 5 (10) ◽  
Author(s):  
Julia Dina ◽  
Justine Hamel ◽  
Denise Antona ◽  
Astrid Vabret
Keyword(s):  
Health Care ◽  
Health Care Worker ◽  
Genome Sequence ◽  
Vaccination Coverage ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Measles Virus ◽  
Wild Type ◽  
Measles Outbreaks ◽  
Care Worker

ABSTRACT Measles outbreaks are regularly reported in European countries despite efforts to improve vaccination coverage. In January 2016, an outbreak occurred in a refugee settlement in Calais, France. We report here the complete genome sequence of a wild-type measles virus isolated from a health care worker (MVi/Calais. FRA/01.16) infected during this outbreak.

scholarly journals Complete Genome Sequence of a Wild-Type Measles Virus Isolated during the Spring 2013 Epidemic in Germany

2014 ◽  
Vol 2 (2) ◽  
Author(s):  
K. M. J. Sparrer ◽  
S. Krebs ◽  
G. Jager ◽  
S. Santibanez ◽  
A. Mankertz ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Measles Virus ◽  
Wild Type

scholarly journals Complete Genome Characterization of Two Wild-Type Measles Viruses from Vietnamese Infants during the 2014 Outbreak

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Bas B. Oude Munnink ◽  
My V. T. Phan ◽  
Paul Kellam ◽  
Matthew Cotten ◽  
Keyword(s):  
Complete Genome ◽  
Measles Virus ◽  
Pediatric Patients ◽  
Wild Type ◽  
Genome Sequences ◽  
Genome Characterization ◽  
Measles Outbreak ◽  
Stool Samples ◽  
Virus Genomes

A large measles virus outbreak occurred across Vietnam in 2014. We identified and obtained complete measles virus genomes in stool samples collected from two diarrheal pediatric patients in Dong Thap Province. These are the first complete genome sequences of circulating measles viruses in Vietnam during the 2014 measles outbreak.

scholarly journals A 44-kb deleted-type copy number variation is associated with decreasing complement component activity and calf mortality in Japanese Black cattle

BMC Genomics ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Shinji Sasaki ◽  
Youko Miki ◽  
Takayuki Ibi ◽  
Hiroyuki Wakaguri ◽  
Yuichi Yoshida ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Copy Number Variation ◽  
Copy Number ◽  
Risk Allele ◽  
Wild Type ◽  
Japanese Black Cattle ◽  
Complement Activity ◽  
Categorical Trait ◽  
Number Variation ◽  
Calf Mortality

Abstract Background Calf mortality generally occurs in calves prior to weaning, which is a serious problem in cattle breeding. Several causative variants of monogenic Mendelian disorders in calf mortality have been identified, whereas genetic factors affecting the susceptibility of calves to death are not well known. To identify variants associated with calf mortality in Japanese Black cattle, we evaluated calf mortality as a categorical trait with a threshold model and performed a genome-wide copy number variation (CNV) association study on calf mortality. Results We identified a 44-kb deleted-type CNV ranging from 103,317,687 to 103,361,802 bp on chromosome 5, which was associated with the mortality of 1–180-day-old calves. The CNV harbored C1RL, a pseudogene, and an IncRNA localized in the C1R and C1S gene cluster, which is a component of the classical complement activation pathway for immune complexes for infectious pathogens. The average complement activity in CNVR_221 homozygotes at postnatal day 7 was significantly lower than that of wild-type animals and heterozygotes. The frequency of the risk allele in dead calves suffering from diarrhea and pneumonia and in healthy cows was 0.35 and 0.28, respectively (odds ratio = 2.2, P = 0.016), suggesting that CNVR_221 was associated with the mortality of Japanese Black calves suffering from an infectious disease. Conclusions This study identified a deleted-type CNV associated with the mortality of 1–180-day-old calves. The complement activity in CNVR_221 homozygotes was significantly lower than that in heterozygotes and wild type animals. The frequency of the risk allele was higher in dead calves suffering from an infectious disease than in healthy cows. These results suggest that the existence of CNVR_221 in calves could be attributed to a reduction in complement activity, which in turn leads to susceptibility to infections. Thus, the risk allele could serve as a useful marker to reduce the mortality of infected Japanese Black calves.

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