scholarly journals Evaluating Plastic Deformation and Damage as Potential Mechanisms for Tendon Inelasticity using a Reactive Modeling Framework

2018 ◽  
Author(s):  
Babak N. Safa ◽  
Andrea H. Lee ◽  
Michael H. Santare ◽  
Dawn M. Elliott
Keyword(s):  
Plastic Deformation ◽  
Mechanical Response ◽  
Independent Set ◽  
The Other ◽  
Modeling Framework ◽  
Validation Data ◽  
Molecular Bond ◽  
Experimental Protocols ◽  
Bond Kinetics ◽  
Comprehensive Framework

ABSTRACTInelastic behaviors, such as softening, a progressive decrease in modulus before failure, occur in tendon andare important aspect in degeneration and tendinopathy. These in elastic behaviors are generally attributed to two potential mechanisms: plastic deformation and damage. However, it is not clear which is primarily responsible.In this study, we evaluated these potential mechanisms of tendon in elasticity by using a recently developed reactive in elasticity model (RIE), which is a structurally-inspired continuum mechanics frame work that models tissue in elasticity based on the molecular bond kinetics. Using RIE, we formulated two material models, one specific toplastic deformation and the other to damage. The models were independently fit to published experimental tensiletests of rat tail tendons. We quantified the inelastic effects and compared the performance of the two models infitting the mechanical response during loading, relaxation, unloading, and reloading phases. Additionally, we validated the models by using the resulting fit parameters to predict an independent set of experimental stress-straincurves from ramp-to-failure tests. Overall, the models were both successful in fitting the experiments and predicting the validation data. However, the results did not strongly favor one mechanism over the other. As a result, to distinguish between plastic deformation and damage, different experimental protocols will be needed. Nevertheless, these findings suggest the potential of RIE as a comprehensive framework for studying tendon inelastic behaviors.

scholarly journals Evaluating Plastic Deformation and Damage as Potential Mechanisms for Tendon Inelasticity Using a Reactive Modeling Framework

2019 ◽  
Vol 141 (10) ◽  
Author(s):  
Babak N. Safa ◽  
Andrea H. Lee ◽  
Michael H. Santare ◽  
Dawn M. Elliott
Keyword(s):  
Plastic Deformation ◽  
Mechanical Response ◽  
Independent Set ◽  
Tensile Tests ◽  
The Other ◽  
Modeling Framework ◽  
Validation Data ◽  
Molecular Bond ◽  
Bond Kinetics ◽  
Comprehensive Framework

Inelastic behaviors, such as softening, a progressive decrease in modulus before failure, occur in tendon and are important aspects in degeneration and tendinopathy. These inelastic behaviors are generally attributed to two potential mechanisms: plastic deformation and damage. However, it is not clear which is primarily responsible. In this study, we evaluated these potential mechanisms of tendon inelasticity by using a recently developed reactive inelasticity model (RIE), which is a structurally inspired continuum mechanics framework that models tissue inelasticity based on the molecular bond kinetics. Using RIE, we formulated two material models, one specific to plastic deformation and the other to damage. The models were independently fit to published macroscale experimental tensile tests of rat tail tendons. We quantified the inelastic effects and compared the performance of the two models in fitting the mechanical response during loading, relaxation, unloading, and reloading phases. Additionally, we validated the models by using the resulting fit parameters to predict an independent set of experimental stress–strain curves from ramp-to-failure tests. Overall, the models were both successful in fitting the experiments and predicting the validation data. However, the results did not strongly favor one mechanism over the other. As a result, to distinguish between plastic deformation and damage, different experimental protocols will be needed. Nevertheless, these findings suggest the potential of RIE as a comprehensive framework for studying tendon inelastic behaviors.

Construction of plastic contact deformation maps on ceramics: a case study on aluminum nitride

1996 ◽  
Vol 54 ◽  
pp. 636-637
Author(s):  
D. L. Callahan
Keyword(s):  
Plastic Deformation ◽  
Aluminum Nitride ◽  
Mechanical Response ◽  
Three Dimensional ◽  
Bright Field Image ◽  
Perfectly Plastic ◽  
Contrast Analysis ◽  
Deformation Patterns

Modern polishing, precision machining and microindentation techniques allow the processing and mechanical characterization of ceramics at nanometric scales and within entirely plastic deformation regimes. The mechanical response of most ceramics to such highly constrained contact is not predictable from macroscopic properties and the microstructural deformation patterns have proven difficult to characterize by the application of any individual technique. In this study, TEM techniques of contrast analysis and CBED are combined with stereographic analysis to construct a three-dimensional microstructure deformation map of the surface of a perfectly plastic microindentation on macroscopically brittle aluminum nitride.The bright field image in Figure 1 shows a lg Vickers microindentation contained within a single AlN grain far from any boundaries. High densities of dislocations are evident, particularly near facet edges but are not individually resolvable. The prominent bend contours also indicate the severity of plastic deformation. Figure 2 is a selected area diffraction pattern covering the entire indentation area.

Electron microscope studies of the plastic deformation of ternary alloys based on GaAs

1990 ◽  
Vol 48 (4) ◽  
pp. 1120-1120
Author(s):  
R. Haswell ◽  
U. Bangert ◽  
P. Charsley
Keyword(s):  
Plastic Deformation ◽  
Electron Microscope ◽  
Room Temperature ◽  
Stacking Faults ◽  
The Other ◽  
Ternary Alloys ◽  
Dislocation Mobility ◽  
Semiconducting Materials ◽  
Micro Indentation

A knowledge of the behaviour of dislocations in semiconducting materials is essential to the understanding of devices which use them . This work is concerned with dislocations in alloys related to the semiconductor GaAs . Previous work on GaAs has shown that microtwinning occurs on one of the <110> rosette arms after indentation in preference to the other . We have shown that the effect of replacing some of the Ga atoms by Al results in microtwinning in both of the rosette arms.In the work to be reported dislocations in specimens of different compositions of Gax Al(1-x) As and Gax In(1-x) As have been studied by using micro indentation on a (001) face at room temperature . A range of electron microscope techniques have been used to investigate the type of dislocations and stacking faults/microtwins in the rosette arms , which are parallel to the [110] and [10] , as a function of composition for both alloys . Under certain conditions microtwinning occurs in both directions . This will be discussed in terms of the dislocation mobility.

scholarly journals The Effect of Different Annealing Strategies on the Microstructure Development and Mechanical Response of Austempered Steels

Metals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1041
Author(s):  
Eliseo Hernandez-Duran ◽  
Luca Corallo ◽  
Tanya Ros-Yanez ◽  
Felipe Castro-Cerda ◽  
Roumen H. Petrov
Keyword(s):  
Mechanical Properties ◽  
Retained Austenite ◽  
Mechanical Response ◽  
Steel Grade ◽  
The Other ◽  
Microstructure Development ◽  
Microstructural Refinement ◽  
Heterogeneous Distribution ◽  
Parent Austenite ◽  
Conventional Annealing

This study focuses on the effect of non-conventional annealing strategies on the microstructure and related mechanical properties of austempered steels. Multistep thermo-cycling (TC) and ultrafast heating (UFH) annealing were carried out and compared with the outcome obtained from a conventionally annealed (CA) 0.3C-2Mn-1.5Si steel. After the annealing path, steel samples were fast cooled and isothermally treated at 400 °C employing the same parameters. It was found that TC and UFH strategies produce an equivalent level of microstructural refinement. Nevertheless, the obtained microstructure via TC has not led to an improvement in the mechanical properties in comparison with the CA steel. On the other hand, the steel grade produced via a combination of ultrafast heating annealing and austempering exhibits enhanced ductility without decreasing the strength level with respect to TC and CA, giving the best strength–ductility balance among the studied steels. The outstanding mechanical response exhibited by the UFH steel is related to the formation of heterogeneous distribution of ferrite, bainite and retained austenite in proportions 0.09–0.78–0.14. The microstructural formation after UFH is discussed in terms of chemical heterogeneities in the parent austenite.

Nitrendipine blocks high potassium contractures but not twitches in rat skeletal muscle

1988 ◽  
Vol 66 (9) ◽  
pp. 1210-1213 ◽  
Author(s):  
G. B. Frank ◽  
L. Konya ◽  
T. Subrahmanyam Sudha
Keyword(s):  
Skeletal Muscle ◽  
Calcium Ions ◽  
Calcium Uptake ◽  
Channel Blocker ◽  
Mechanical Response ◽  
Extracellular Calcium ◽  
The Other ◽  
Rat Skeletal Muscle ◽  
Potassium Depolarization ◽  
High Potassium

The effects of the organic calcium channel blocker nitrendipine was tested on electrically evoked twitches and on potassium depolarization-induced contractures of rat lumbricalis muscles. Nitrendipine (10−7 to 5 × 10−5 M) blocked only the potassium contractures. It was concluded that blocking calcium uptake through the slow voltage-senstitive calcium channels during potassium depolarization blocks the mechanical response of the muscle. Thus extracellular calcium ions are required for the excitation–contraction (E–C) coupling during depolarization contractures. On the other hand, electrically evoked twitches were not affected by nitrendipine; therefore, extracellular calcium ions entering via the slow voltage-sensitive channels are not required for E–C coupling during the twitch.

Molecular Dynamics Modeling the Nano-Identation of Titanium

2021 ◽  
Author(s):  
Peiqiang Yang ◽  
Xueping Zhang ◽  
Zhenqiang Yao ◽  
Rajiv Shivpuri
Keyword(s):  
Molecular Dynamics ◽  
Plastic Deformation ◽  
Titanium Alloys ◽  
Large Scale ◽  
Mechanical Response ◽  
Pure Titanium ◽  
Dynamics Modeling ◽  
Dynamics Model ◽  
Nano Indentation ◽  
Molecular Dynamics Modeling

Abstract Titanium alloys’ excellent mechanical and physical properties make it the most popular material widely used in aerospace, medical, nuclear and other significant industries. The study of titanium alloys mainly focused on the macroscopic mechanical mechanism. However, very few researches addressed the nanostructure of titanium alloys and its mechanical response in Nano-machining due to the difficulty to perform and characterize nano-machining experiment. Compared with nano-machining, nano-indentation is easier to characterize the microscopic plasticity of titanium alloys. This research presents a nano-indentation molecular dynamics model in titanium to address its microstructure alteration, plastic deformation and other mechanical response at the atomistic scale. Based on the molecular dynamics model, a complete nano-indentation cycle, including the loading and unloading stages, is performed by applying Large-scale Atomic/Molecular Massively Parallel Simulator (LAMMPS). The plastic deformation mechanism of nano-indentation of titanium with a rigid diamond ball tip was studied under different indentation velocities. At the same time, the influence of different environment temperatures on the nano-plastic deformation of titanium is analyzed under the condition of constant indentation velocity. The simulation results show that the Young’s modulus of pure titanium calculated based on nano-indentation is about 110GPa, which is very close to the experimental results. The results also show that the mechanical behavior of titanium can be divided into three stages: elastic stage, yield stage and plastic stage during the nano-indentation process. In addition, indentation speed has influence on phase transitions and nucleation of dislocations in the range of 0.1–1.0 Å/ps.

Contrasting cybersecurity implementation frameworks (CIF) from three countries

2019 ◽  
Vol 27 (3) ◽  
pp. 373-392
Author(s):  
Adenekan Dedeke ◽  
Katherine Masterson
Keyword(s):  
Risk Management ◽  
Design Methodology ◽  
Document Analysis ◽  
Decision Makers ◽  
The Other ◽  
Management Approach ◽  
Content Type ◽  
Assessment Matrix ◽  
Comprehensive Framework ◽  
Country Specific

Purpose This paper aims to explore the evolution of a trend in which countries are developing or adopting cybersecurity implementation frameworks that are intended to be used nationally. This paper contrasts the cybersecurity frameworks that have been developed in three countries, namely, Australia, UK and USA. Design/methodology/approach The paper uses literature review and qualitative document analysis for the study. The paper developed and used an assessment matrix as its coding protocol. The contents of the three cybersecurity frameworks were then scored to capture the degree to which they covered the themes/items of the cybersecurity assessment matrix. Findings The analysis found that the three cybersecurity frameworks are oriented toward the risk management approach. However, the frameworks also had notable differences with regard to the security domains that they cover. For example, one of the frameworks did not offer guidelines with regard to what to do to respond to attacks or to plan for recovery. Originality/value The results of this study are beneficial to policymakers in the three countries targeted, as they are able to gain insights about how their cybersecurity frameworks compares to those of the other two countries. Such knowledge would be useful as decision-makers take steps to improve their existing frameworks. The results of this study are also beneficial to executives who have branches in all three countries. In such cases, security professionals could deploy the most comprehensive framework across all three countries and then extend the deployment in each location to meet country-specific requirements.

The Influence of the Fatigue Cycles Number on Material Hardness

2014 ◽  
Vol 658 ◽  
pp. 195-200
Author(s):  
Viorel Goanta
Keyword(s):  
Plastic Deformation ◽  
Indentation Load ◽  
The Other ◽  
Stress Cycle ◽  
Elastic Range ◽  
Maximum Value ◽  
Material Hardness ◽  
Stress Fatigue ◽  
Minimum Force ◽  
Maximum Minimum

In this paper we present the experimental results obtained after determining hardness on samples previously subjected to fatigue. Firstly, 6 identical samples have been subjected to stress fatigue in the elastic range a number of 105, 5∙105, 106, 2∙106, 3∙106 and 4∙106 cycles. For all samples we used the same form of stress cycle, respectively, sinusoidal, and the same values of maximum, minimum force and the amplitude of the cycle (50 kN, 30 kN and 10 kN). It is noted that the maximum value of the load was less than that at which samples fall within the plastic deformation. Therefore, the original loading of samples was performed in the elastic range. For each of the six samples determinations of levels of hardness were performed, with the value of indentation load of 10 kgf. Indentations were made on the samples, along the length of the calibration, at a distance of 10 mm one within the other. As it will be seen below, in the areas with the highest hardness were performed several indentations, in order to determine the highest hardness area, which, in our view, also presents the largest degree of plastic deformation.

Comparison of the Neuromuscular Blocking Effect of Atracurium and Vecuronium on the Adductor Pollicis and the Geniohyoid Muscle in Humans 

1995 ◽  
Vol 82 (3) ◽  
pp. 649-654 ◽  
Author(s):  
G. D'Honneur ◽  
B. Guignard ◽  
V. Slavov ◽  
R. Ruggler ◽  
P. Duvaldestin
Keyword(s):  
Mechanical Response ◽  
Elective Surgery ◽  
Onset Time ◽  
Blocking Agent ◽  
Force Transducer ◽  
Neuromuscular Blocking ◽  
Neuromuscular Blocking Agent ◽  
Adductor Pollicis ◽  
The Other ◽  
Airway Patency

Background Residual paralysis of suprahyoid muscles may occur when the adductor pollicis response has completely recovered after the administration of a neuromuscular blocking agent. The response of the geniohyoid muscle to intubating doses of muscle relaxants is evaluated and compared to that of adductor pollicis. Methods Sixteen patients undergoing elective surgery under general anesthesia were given 5-7 mg.kg-1 thiopental and 2 micrograms.kg-1 fentanyl intravenously for induction of anesthesia. Eight (half) patients then received 0.5 mg.kg-1 atracurium, and the other eight received 0.1 mg.kg-1 vecuronium. The evoked response (twitch height, TH) of the adductor pollicis was monitored by measuring the integrated electromyographic response (AP EMG) on one limb and the mechanical response, using a force transducer (AP force), on the other. The activity of geniohyoid muscle (GH EMG) was measured using submental percutaneous electrodes. The following variables were measured: maximal TH depression; onset time for neuromuscular blockade to 50%, 90%, and maximal TH depression (OT50, OT90, and OTmax); times between administration of neuromuscular blocking agent and TH recovery to 10%, 25%, 50%, 75%, and 90% of control; and time for return of train-of-four ratio to return to 0.7. Results The principal findings were (1) OTmax was significantly (P &lt; 0.01) shorter for geniohyoid than for adductor pollicis after either atracurium or vecuronium (OTmax was 216, 256, and 175 s for AP force, AP EMG, and GH EMG, with atracurium and 181, 199, and 144 s with vecuronium, respectively), and (2) the evoked EMG of geniohyoid recovered at the same speed as the EMG of adductor pollicis after an intubating dose of atracurium or vecuronium (recovery of TH to 75% of control at 50, 48, 42 min with AP force, AP EMG, and GH EMG with atracurium and 46, 45, and 42 min with vecuronium, respectively). Conclusions Once the adductor pollicis response has returned to normal values after a single intubating dose of atracurium or vecuronium, the risk of residual depression of the TH of the geniohyoid muscle, one of the principal muscles contributing to airway patency, appears unlikely.

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