scholarly journals Inter- and intracellular colonization of Arabidopsis roots by endophytic actinobacteria and the impact of plant hormones on their antimicrobial activity

2017 ◽  
Author(s):  
Anne van der Meij ◽  
Joost Willemse ◽  
Martinus A. Schneijderberg ◽  
René Geurts ◽  
Jos M. Raaijmakers ◽  
...  
Keyword(s):  
Plant Hormones ◽  
Antibiotic Production ◽  
Close Association ◽  
Root Tissue ◽  
Substantial Part ◽  
Natural Ecosystem ◽  
Life Styles ◽  
Subsequent Exposure ◽  
The Impact ◽  
Endophytic Actinobacteria

ABSTRACTMany actinobacteria live in close association with eukaryotes like fungi, insects, animals and plants. Plant-associated actinobacteria display (endo)symbiotic, saprophytic or pathogenic life styles, and can make up a substantial part of the endophytic community. Here, we characterised endophytic actinobacteria isolated from root tissue ofArabidopsis thaliana(Arabidopsis) plants grown in soil from a natural ecosystem. Many of these actinobacteria belong to the family ofStreptomycetaceaewithStreptomyces olivochromogenesandStreptomyces claviferas well represented species. When seeds of Arabidopsis were inoculated with spores ofStreptomycesstrain coa1, which shows high similarity toS. olivochromogenes, roots were colonised intercellularly and, unexpectedly, also intracellularly. Subsequent exposure of endophytic isolates to plant hormones typically found in root and shoot tissues of Arabidopsis led to altered antibiotic production againstEscherichia coliandBacillus subtilis. Taken together, our work reveals remarkable colonization patterns of endophytic streptomycetes with specific traits that may allow a competitive advantage inside root tissue.

scholarly journals Inter- and intracellular colonization of Arabidopsis roots by endophytic actinobacteria and the impact of plant hormones on their antimicrobial activity

2018 ◽  
Vol 111 (5) ◽  
pp. 679-690 ◽  
Author(s):  
Anne van der Meij ◽  
Joost Willemse ◽  
Martinus A. Schneijderberg ◽  
René Geurts ◽  
Jos M. Raaijmakers ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Plant Hormones ◽  
The Impact ◽  
Endophytic Actinobacteria

scholarly journals Consideration of Gut Microbiome in Murine Models of Diseases

2021 ◽  
Vol 9 (5) ◽  
pp. 1062
Author(s):  
Chunye Zhang ◽  
Craig L. Franklin ◽  
Aaron C. Ericsson
Keyword(s):  
Animal Models ◽  
Mouse Models ◽  
Biomedical Research ◽  
Gut Microbiome ◽  
Close Association ◽  
Disease Model ◽  
Potential Contributor ◽  
Potential Factors ◽  
Models Of Disease ◽  
The Impact

The gut microbiome (GM), a complex community of bacteria, viruses, protozoa, and fungi located in the gut of humans and animals, plays significant roles in host health and disease. Animal models are widely used to investigate human diseases in biomedical research and the GM within animal models can change due to the impact of many factors, such as the vendor, husbandry, and environment. Notably, variations in GM can contribute to differences in disease model phenotypes, which can result in poor reproducibility in biomedical research. Variation in the gut microbiome can also impact the translatability of animal models. For example, standard lab mice have different pathogen exposure experiences when compared to wild or pet store mice. As humans have antigen experiences that are more similar to the latter, the use of lab mice with more simplified microbiomes may not yield optimally translatable data. Additionally, the literature describes many methods to manipulate the GM and differences between these methods can also result in differing interpretations of outcomes measures. In this review, we focus on the GM as a potential contributor to the poor reproducibility and translatability of mouse models of disease. First, we summarize the important role of GM in host disease and health through different gut–organ axes and the close association between GM and disease susceptibility through colonization resistance, immune response, and metabolic pathways. Then, we focus on the variation in the microbiome in mouse models of disease and address how this variation can potentially impact disease phenotypes and subsequently influence research reproducibility and translatability. We also discuss the variations between genetic substrains as potential factors that cause poor reproducibility via their effects on the microbiome. In addition, we discuss the utility of complex microbiomes in prospective studies and how manipulation of the GM through differing transfer methods can impact model phenotypes. Lastly, we emphasize the need to explore appropriate methods of GM characterization and manipulation.

scholarly journals Inadequate management of natural ecosystem in the Brazilian Amazon region results in the emergence and reemergence of arboviruses

2001 ◽  
Vol 17 (suppl) ◽  
pp. S155-S164 ◽  
Author(s):  
Pedro F. C. Vasconcelos ◽  
Amélia P. A. Travassos da Rosa ◽  
Sueli G. Rodrigues ◽  
Elizabeth S. Travassos da Rosa ◽  
Nicolas Dégallier ◽  
...  
Keyword(s):  
Environmental Changes ◽  
Epidemiological Data ◽  
Brazilian Amazon ◽  
Host Population ◽  
Amazon Region ◽  
Laboratory Animals ◽  
Natural Ecosystem ◽  
Brazilian Amazon Region ◽  
Mining Dam ◽  
The Impact

A total of 187 different species of arboviruses and other viruses in vertebrates were identified at the Evandro Chagas Institute (IEC) from 1954 to 1998, among more than 10,000 arbovirus strains isolated from humans, hematophagous insects, and wild and sentinel vertebrates. Despite intensive studies in the Brazilian Amazon region, especially in Pará State, very little is known about most of these viruses, except for information on date, time, source, and method of isolation, as well as their capacity to infect laboratory animals. This paper reviews ecological and epidemiological data and analyzes the impact of vector and host population changes on various viruses as a result of profound changes in the natural environment. Deforestation, mining, dam and highway construction, human colonization, and urbanization were the main manmade environmental changes associated with the emergence and/or reemergence of relevant arboviruses, including some known pathogens for humans.

scholarly journals Cell responses to the impact of physiological doses of ultraviolet radiation and their modulation by plant polyphenols

2019 ◽  
pp. 13-21
Author(s):  
Vladimir A. Kostyuk ◽  
Ahmed Albuhaydar ◽  
Alla I. Potapovich ◽  
Lyudmila G. Korkinа
Keyword(s):  
Experimental Data ◽  
Ultraviolet Radiation ◽  
Signaling Pathways ◽  
Polyphenolic Compounds ◽  
Plant Polyphenols ◽  
Inflammatory Signaling ◽  
Cell Responses ◽  
Subsequent Exposure ◽  
Cultured Human Cells ◽  
The Impact

In this study it was investigated the responses of cultured human cells – keratinocytes and fibroblasts to physiological doses of ultraviolet radiation (UVR) applied with or without plant polyphenolic compounds: rutin, quercetin, taxofolin, silybin and baikalein. Experimental data obtained in this work indicate the presence of synergism in the action of physiological doses of UVR and plant polyphenolic compounds on inflammatory signaling pathways in keratinocytes and fibroblasts. It is concluded that the identified synergies can contribute to the adaptation of the skin to subsequent exposure to UVR, and thus be one of the photoprotective mechanisms of the plant polyphenolic compounds.

scholarly journals Legal procuring of international information/cyber security of the digital economy: economic and legal aspects

E-Management ◽  
2019 ◽  
pp. 61-66
Author(s):  
L. O. Gontar’
Keyword(s):  
European Union ◽  
Cyber Security ◽  
Law And Economics ◽  
Integrated Approach ◽  
Legal Regulation ◽  
Legal Aspects ◽  
Digital Economy ◽  
Substantial Part ◽  
The European Union ◽  
The Impact

The article considers a problem of the definition of the digital economy, as well as presents a new theme on the legal procuring of international cyber security. The above mentioned new direction serves as an indicator of possible interdisciplinary research in the field of law and economics in the sphere of digital processes. As a justification the acts of the European Union have been adduced and their characteristic features, which consist in consideration of a substantial part of digital economy (economic party) have been allocated. This integration association has a unique structure and history, but the process of regulating the digital economy in the European Union began not so long ago. The European Union is one of the few integration associations that has started to work on improving the mechanisms of legal regulation of the digital market. This circumstance certainly affects the development of an integrated approach to the understanding of the digital economy, as well as further actualizes the issue of considering the legal procuring of international cyber security of this phenomenon. Legal procuring of security is a new direction in the international legal field, which will allow to consider the legal aspects in demand in the digital economy. The challenges in relation to international cyber security and the impact of the conceptual apparatus on the issues of the legal procuring of the security of the digital economy have been considered. It is important to note that the article suggests possible solutions to the problem posed. At the end of the article three proposals for improving approaches to the security of the digital economy have been elaborated. In terms of their qualitative characteristics, the proposals, undoubtedly, relate to legal and technical aspects, but also solutions regarding the conceptual component of the legal procuring of the security have been presented.

scholarly journals Effects of Baekje Weir Operation on the Stream–Aquifer Interaction in the Geum River Basin, South Korea

Water ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 2984
Author(s):  
Hyeonju Lee ◽  
Min-Ho Koo ◽  
Byong Wook Cho ◽  
Yong Hwa Oh ◽  
Yongje Kim ◽  
...  
Keyword(s):  
South Korea ◽  
Groundwater Flow ◽  
Groundwater Quality ◽  
Flow System ◽  
Natural Ecosystem ◽  
Visual Modflow ◽  
Ecosystem Recovery ◽  
Groundwater Use ◽  
Groundwater Flow System ◽  
The Impact

Hydraulic structures have a significant impact on riverine environment, leading to changes in stream–aquifer interactions. In South Korea, 16 weirs were constructed in four major rivers, in 2012, to secure sufficient water resources, and some weirs operated periodically for natural ecosystem recovery from 2017. The changed groundwater flow system due to weir operation affected the groundwater level and quality, which also affected groundwater use. In this study, we analyzed the changes in the groundwater flow system near the Geum River during the Baekje weir operation using Visual MODFLOW Classic. Groundwater data from 34 observational wells were evaluated to analyze the impact of weir operation on stream–aquifer interactions. Accordingly, the groundwater discharge rates increased from 0.23 to 0.45 cm/day following the decrease in river levels owing to weir opening, while the hydrological condition changed from gaining to losing streams following weir closure. The variation in groundwater flow affected the groundwater quality during weir operation, changing the groundwater temperature and electrical conductivity (EC). Our results suggest that stream–aquifer interactions are significantly affected by weir operation, consequently, these repeated phenomena could influence the groundwater quality and groundwater use.

The Arab Spring and the International Defense Market

2020 ◽  
pp. 1-19
Author(s):  
Jeroen Klomp
Keyword(s):  
Political Violence ◽  
Abnormal Return ◽  
Arab Spring ◽  
Substantial Part ◽  
Dynamic Panel Model ◽  
Panel Model ◽  
Stock Market Return ◽  
The One ◽  
The Arab Spring ◽  
The Impact

Abstract The aim of this study is to analyze the impact of the political violence during the Arab Spring on the stock market return of international defense firms. The direction of this impact is not directly straightforward as the civil unrests influence the expectations of investors in two opposite ways. On the one hand, investors might expect that when the peaceful demonstrations were turned into violent events, the Arab governments involved will start acquiring more military-strategic goods to repress the protests or send a strong signal of power to ensure their stay in office. However, on the other hand, when the popular protests escalated, investors, perhaps, became more concerned about the possible imposition of international military sanctions against the Arab Spring countries to restore peace and protect human rights. The main empirical findings of a dynamic panel model clearly confirm this pattern and point out that when the Arab Spring originated, the abnormal return of international defense stocks starts to rise immediately. However, in the course of time, the concerns of the introduction of arms embargoes become stronger and eventually start to dominate, causing the abnormal return to fall again, while the idiosyncratic risk began to fall due to enhanced diversification. It turns out that firm-specific factors can explain a substantial part of the effect found. For instance, the reaction of investors to the Arab Spring is significantly larger for firms that produce predominantly military goods.

scholarly journals Chemical sensing of plant stress at the ecosystem scale

2008 ◽  
Vol 5 (5) ◽  
pp. 1287-1294 ◽  
Author(s):  
T. Karl ◽  
A. Guenther ◽  
A. Turnipseed ◽  
E. G. Patton ◽  
K. Jardine
Keyword(s):  
Plant Hormones ◽  
Systemic Acquired Resistance ◽  
Chilling Injury ◽  
Plant Stress ◽  
Acquired Resistance ◽  
Warning Signal ◽  
Ambient Air ◽  
Aerosol Formation ◽  
Night Time ◽  
The Impact

Abstract. Significant ecosystem-scale emissions of methylsalicylate (MeSA), a semivolatile plant hormone thought to act as the mobile signal for systemic acquired resistance (SAR), were observed in an agroforest. Our measurements show that plant internal defence mechanisms can be activated in response to temperature stress and are modulated by water availability on large scales. Highest MeSA fluxes (up to 0.25 mg/m2/h) were observed after plants experienced ambient night-time temperatures of ~7.5°C followed by a large daytime temperature increase (e.g. up to 22°C). Under these conditions estimated night-time leaf temperatures were as low as ~4.6°C, likely inducing a response to prevent chilling injury. Our observations imply that plant hormones can be a significant component of ecosystem scale volatile organic compound (VOC) fluxes (e.g. as high as the total monoterpene (MT) flux) and therefore contribute to the missing VOC budget. If generalized to other ecosystems and different types of stresses these findings suggest that semivolatile plant hormones have been overlooked by investigations of the impact of biogenic VOCs on aerosol formation events in forested regions. Our observations show that the presence of MeSA in canopy air serves as an early chemical warning signal indicating ecosystem-scale stresses before visible damage becomes apparent. As a chemical metric, ecosystem emission measurements of MeSA in ambient air could therefore support field studies investigating factors that adversely affect plant growth.

scholarly journals The impact of Schiff bases on antibiotic production by Streptomyces hygroscopicus

2009 ◽  
Vol 19 (7) ◽  
pp. 690-697 ◽  
Author(s):  
Slavica B. Ilić ◽  
Sandra S. Konstantinović ◽  
Dragiša S. Savić ◽  
Vlada B. Veljković ◽  
G. Gojgić-Cvijović
Keyword(s):  
Schiff Bases ◽  
Antibiotic Production ◽  
Streptomyces Hygroscopicus ◽  
The Impact
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