scholarly journals Less is More: Oligomer extraction and hydrothermal annealing increase PDMS bonding forces for new microfluidics assembly and for biological studies

2017 ◽  
Author(s):  
L. J. Millet ◽  
A. Jain ◽  
M. U. Gillette
Keyword(s):  
Network Formation ◽  
Low Cost ◽  
Covalent Bond ◽  
High Strength ◽  
Combined Processes ◽  
Less Is More ◽  
Cell Network ◽  
Biological Studies ◽  
Clinical Biology ◽  
Network Studies

Key determinants in the emergence of complex cellular morphologies and functions are cues in the micro-environment. Primary among these is the presence of neighboring cells as networks form. Therefore, for high-resolution analysis, it is crucial to develop micro-environments that permit exquisite control of network formation. This is especially true in cell science, tissue engineering, and clinical biology. We introduce a new approach for assembling polydimethylsiloxane (PDMS)-based microfluidic environments that enhances cell network formation and analyses. We report that the combined processes of PDMS solvent-extraction (E-PDMS) and hydrothermal annealing create unique conditions that produce high-strength bonds between E-PDMS and glass – properties not associated with conventional PDMS. Extraction followed by hydrothermal annealing removes unbound oligomers, promotes polymer cross-linking, facilitates covalent bond formation with glass, and retains the highest biocompatibility. Our extraction protocol accelerates oligomer removal from 5 to 2 days. Resulting microfluidic platforms are uniquely suited for cell-network studies owing to high bond strengths, effectively corralling cellular extensions and eliminating harmful oligomers. We demonstrate simple, simultaneous actuation of multiple microfluidic domains for invoking ATP- and glutamate-induced Ca2+ signaling in glial-cell networks. These low-cost, simple E-PMDS modifications and flow manipulations further enable microfluidic technologies for cell-signaling and network studies as well as novel applications.

Decomposition of the metastable beta titanium alloy Ti-15-3

1983 ◽  
Vol 41 ◽  
pp. 264-265
Author(s):  
Y. L. Chen ◽  
S. Fujlshiro
Keyword(s):  
Low Cost ◽  
High Strength ◽  
Alpha Phase ◽  
Thick Sheet ◽  
Omega Phase ◽  
Beta Titanium Alloy ◽  
Beta Titanium ◽  
Beta Matrix ◽  
Metastable Beta ◽  
Very High

Metastable beta titanium alloys have been known to have numerous advantages such as cold formability, high strength, good fracture resistance, deep hardenability, and cost effectiveness. Very high strength is obtainable by precipitation of the hexagonal alpha phase in a bcc beta matrix in these alloys. Precipitation hardening in the metastable beta alloys may also result from the formation of transition phases such as omega phase. Ti-15-3 (Ti-15V- 3Cr-3Al-3Sn) has been developed recently by TIMET and USAF for low cost sheet metal applications. The purpose of the present study was to examine the aging characteristics in this alloy.The composition of the as-received material is: 14.7 V, 3.14 Cr, 3.05 Al, 2.26 Sn, and 0.145 Fe. The beta transus temperature as determined by optical metallographic method was about 770°C. Specimen coupons were prepared from a mill-annealed 1.2 mm thick sheet, and solution treated at 827°C for 2 hr in argon, then water quenched. Aging was also done in argon at temperatures ranging from 316 to 616°C for various times.

INCONEL ALLOY X-750

Alloy Digest ◽  
1966 ◽  
Vol 15 (7) ◽  
Keyword(s):  
Gas Turbines ◽  
Rupture Strength ◽  
Low Cost ◽  
High Strength ◽  
Heat Treating ◽  
Chromium Alloy ◽  
Cryogenic Temperatures ◽  
Inconel Alloy ◽  
Nickel Chromium ◽  
Corrosion And Oxidation

Abstract INCONEL alloy X-750 is an age-hardenable, nickel-chromium alloy used for its corrosion and oxidation resistance and high creep rupture strength at temperature up to 1500 F. It also has excellent properties at cryogenic temperatures. It was originally developed for use in gas turbines, but because of its low cost, high strength and weldability it has become the standards choice for a wide variety of applications. This datasheet provides information on composition, physical properties, elasticity, and tensile properties as well as creep and fatigue. It also includes information on forming, heat treating, machining, joining, and surface treatment. Filing Code: Ni-115. Producer or source: Huntington Alloy Products Division, An INCO Company.

Bamboo Waste-based Bio-composite Substance: An application for Low-cost Construction Materials

2020 ◽  
Vol 4 (1) ◽  
pp. 41-48
Author(s):  
Teodoro Astorga Amatosa ◽  
Michael E. Loretero
Keyword(s):  
Composite Materials ◽  
Sea Water ◽  
Raw Materials ◽  
Low Cost ◽  
Construction Materials ◽  
Single Layer ◽  
High Strength ◽  
Green Technology ◽  
Experimental Medium ◽  
Natural Treatment

Bamboo is a lightweight and high-strength raw materials that encouraged researchers to investigate and explore, especially in the field of biocomposite and declared as one of the green-technology on the environment as fully accountable as eco-products. This research was to assess the technical feasibility of making single-layer experimental Medium-Density Particleboard panels from the bamboo waste of a three-year-old (Dendrocalamus asper). Waste materials were performed to produce composite materials using epoxy resin (C21H25C105) from a natural treatment by soaking with an average of pH 7.6 level of sea-water. Three different types of MDP produced, i.e., bamboo waste strip MDP (SMDP), bamboo waste chips MDP (CMDP) and bamboo waste mixed strip-chips MDP (MMDP) by following the same process. The experimental panels tested for their physical-mechanical properties according to the procedures defined by ASTM D1037-12. Conclusively, even the present study shows properties of MDP with higher and comparable to other composite materials; further research must be given better attention as potential substitute to be used as hardwood materials, especially in the production, design, and construction usage.

Causes of gear pump fails and methods for their elimination

2020 ◽  
pp. 98-107
Author(s):  
Vitaliy A. Zuyevskiy ◽  
Daniil O. Klimyuk ◽  
Ivan A. Shemberev
Keyword(s):  
Adhesion Strength ◽  
Production Systems ◽  
Low Cost ◽  
High Strength ◽  
Strength Properties ◽  
Research Purpose ◽  
Working Fluid ◽  
Gear Pump ◽  
Repair Service ◽  
Recovery Method

Gear pumps are an important element of many production systems and their replacement in case of failure can be quite expensive, so it is important to have a modern and well-tuned technology for their recovery. There are many methods for restoring the pump's performance, depending on the reason that led to its failure. (Research purpose) The research purpose is in determining what causes most often lead to loss of pump performance, and developing a recovery method that provides the greatest post-repair service life of the pump and low cost of repair. (Materials and methods) Authors took into account that the applied coatings must have sufficient adhesion strength and resistance to mechanical, thermal and corrosion loads during operation. It was found that most often significant leaks of the working fluid, leading to failure, occur due to an increase in the gap between the inner surface of the housing and the gears due to active wear of the housing wells. Authors determined that the method of electric spark treatment of worn-out housing wells is best suited to perform the task (a large post-repair resource and low costs). (Results and discussion) It was found by laboratory studies of the adhesion strength of electric spark coatings with various electrodes that the best transfer of the material to the substrate is provided by bronze electrodes BrMKts3-1. It was noted that the coatings applied using the BrMKts3-1 electrode have high strength properties. (Conclusions) Research conducted in the center for collective use "Nano-Center" VIM confirmed the possibility of effective recovery of the gear pump by electric spark treatment.

scholarly journals Acoustic Cell Patterning in Hydrogel for Three-Dimensional Cell Network Formation

Micromachines ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 3
Author(s):  
Kyo-in Koo ◽  
Andreas Lenshof ◽  
Le Thi Huong ◽  
Thomas Laurell
Keyword(s):  
Network Formation ◽  
Umbilical Vein ◽  
Three Dimensional ◽  
Extrusion Process ◽  
Fibroblast Cells ◽  
Glass Capillary ◽  
Cell Network ◽  
Significant Difference ◽  
The One ◽  
Umbilical Vein Endothelial Cells

In the field of engineered organ and drug development, three-dimensional network-structured tissue has been a long-sought goal. This paper presents a direct hydrogel extrusion process exposed to an ultrasound standing wave that aligns fibroblast cells to form a network structure. The frequency-shifted (2 MHz to 4 MHz) ultrasound actuation of a 400-micrometer square-shaped glass capillary that was continuously perfused by fibroblast cells suspended in sodium alginate generated a hydrogel string, with the fibroblasts aligned in single or quadruple streams. In the transition from the one-cell stream to the four-cell streams, the aligned fibroblast cells were continuously interconnected in the form of a branch and a junction. The ultrasound-exposed fibroblast cells displayed over 95% viability up to day 10 in culture medium without any significant difference from the unexposed fibroblast cells. This acoustofluidic method will be further applied to create a vascularized network by replacing fibroblast cells with human umbilical vein endothelial cells.

scholarly journals Design of Low-Cost and High-Strength Titanium Alloys Using Pseudo-Spinodal Mechanism through Diffusion Couple Technology and CALPHAD

Materials ◽  
2021 ◽  
Vol 14 (11) ◽  
pp. 2910
Author(s):  
Chaoyi Ding ◽  
Chun Liu ◽  
Ligang Zhang ◽  
Di Wu ◽  
Libin Liu
Keyword(s):  
Diffusion Couple ◽  
Titanium Alloys ◽  
High Throughput ◽  
Volume Fraction ◽  
Raw Materials ◽  
Low Cost ◽  
High Strength ◽  
High Yield ◽  
Α Phase ◽  
Cr System

The high cost of development and raw materials have been obstacles to the widespread use of titanium alloys. In the present study, the high-throughput experimental method of diffusion couple combined with CALPHAD calculation was used to design and prepare the low-cost and high-strength Ti-Al-Cr system titanium alloy. The results showed that ultra-fine α phase was obtained in Ti-6Al-10.9Cr alloy designed through the pseudo-spinodal mechanism, and it has a high yield strength of 1437 ± 7 MPa. Furthermore, application of the 3D strength model of Ti-6Al-xCr alloy showed that the strength of the alloy depended on the volume fraction and thickness of the α phase. The large number of α/β interfaces produced by ultra-fine α phase greatly improved the strength of the alloy but limited its ductility. Thus, we have demonstrated that the pseudo-spinodal mechanism combined with high-throughput diffusion couple technology and CALPHAD was an efficient method to design low-cost and high-strength titanium alloys.

scholarly journals Heterogeneous lamella structure unites ultrafine-grain strength with coarse-grain ductility

2015 ◽  
Vol 112 (47) ◽  
pp. 14501-14505 ◽  
Author(s):  
Xiaolei Wu ◽  
Muxin Yang ◽  
Fuping Yuan ◽  
Guilin Wu ◽  
Yujie Wei ◽  
...  
Keyword(s):  
Large Scale ◽  
Low Cost ◽  
High Strength ◽  
Back Stress ◽  
Coarse Grained ◽  
Ultrafine Grain ◽  
Asymmetric Rolling ◽  
Dislocation Hardening ◽  
Ultrafine Grained ◽  
Lamella Structure

Grain refinement can make conventional metals several times stronger, but this comes at dramatic loss of ductility. Here we report a heterogeneous lamella structure in Ti produced by asymmetric rolling and partial recrystallization that can produce an unprecedented property combination: as strong as ultrafine-grained metal and at the same time as ductile as conventional coarse-grained metal. It also has higher strain hardening than coarse-grained Ti, which was hitherto believed impossible. The heterogeneous lamella structure is characterized with soft micrograined lamellae embedded in hard ultrafine-grained lamella matrix. The unusual high strength is obtained with the assistance of high back stress developed from heterogeneous yielding, whereas the high ductility is attributed to back-stress hardening and dislocation hardening. The process discovered here is amenable to large-scale industrial production at low cost, and might be applicable to other metal systems.

SYNTHESIS AND CHARACTERISATION OF WOVENROVING GLASS MAT FOR EPOXYCOMPOSITES

2020 ◽  
Vol 15 (4) ◽  
Author(s):  
Mahesh Mallampati ◽  
Sreekanth Mandalapu ◽  
Govidarajulu C
Keyword(s):  
Tensile Strength ◽  
Glass Fiber ◽  
Low Cost ◽  
Weight Ratio ◽  
High Strength ◽  
Hardness Test ◽  
Industrial Applications ◽  
Sem Analysis ◽  
Low Thermal Expansion ◽  
Manufacturing Techniques

The composite materials are replacing the traditional materials because oftheir superior properties such as high tensile strength, low thermal expansion, high strength to weight ratio, low cost, lightweight, high specific modulus, renewability and biodegradability which are the most basic & common attractive features of composites that make them useful for industrial applications. The developments of new materials are on the anvil and are growing day by day. The efforts to produce economically attractive composite components have resulted in several innovative manufacturing techniques currently being used in the composites industry. Generally, composites consist of mainly two phases i.e., matrix and fiber. In this study, woven roving mats (E-glass fiber orientation (-45°/45°,0°/90°, - 45°/45°),UD450GSM)were cut in measured dimensions and a mixture of Epoxy Resin (EPOFINE-556, Density-1.15gm/cm3), Hardener (FINE HARDTM 951, Density- 0.94 gm/cm3) and Acetone [(CH3)2CO, M= 38.08 g/mol] was used to manufacture the glass fiber reinforced epoxy composite by hand lay-up method. Mechanical properties such as tensile strength, SEM analysis, hardness test, density tests are evaluated.

Third generation of advanced high-strength steels: Processing routes and properties

2016 ◽  
Vol 233 (2) ◽  
pp. 209-238 ◽  
Author(s):  
Tarun Nanda ◽  
Vishal Singh ◽  
Virender Singh ◽  
Arnab Chakraborty ◽  
Sandeep Sharma
Keyword(s):  
Automobile Industry ◽  
Second Generation ◽  
Low Cost ◽  
High Strength Steels ◽  
High Strength ◽  
Cost Effective ◽  
Processing Route ◽  
Third Generation ◽  
Specific Strength ◽  
Advanced High Strength Steels

The automobile industry is presently focusing on processing of advanced steels with superior strength–ductility combination and lesser weight as compared to conventional high-strength steels. Advanced high-strength steels are a new class of materials to meet the need of high specific strength while maintaining the high formability required for processing, and that too at reasonably low cost. First and second generation of advanced high-strength steels suffered from some limitations. First generation had high strength but low formability while second generation possessed both strength and ductility but was not cost effective. Amongst the different types of advanced high-strength steels grades, dual-phase steels, transformation-induced plasticity steels, and complex phase steels are considered as very good options for being extended into third generation advanced high-strength steels. The present review presents the various processing routes for these grades developed and discussed by different authors. A novel processing route known as quenching and partitioning route is also discussed. The review also discusses the resulting microstructures and mechanical properties achieved under various processing conditions. Finally, the key findings with regards to further research required for the processing of advanced high-strength steels of third generation have been discussed.

Alumina fibre FP

1980 ◽  
Vol 294 (1411) ◽  
pp. 411-417 ◽  
Keyword(s):  
Tensile Strength ◽  
Elevated Temperatures ◽  
Low Cost ◽  
Ferrous Metal ◽  
High Strength ◽  
Textile Fibre ◽  
Continuous Filament ◽  
Fibre Spinning ◽  
Metal Castings ◽  
Room Temperature Strength

A new experimental inorganic fibre currently under development at the Du Pont Company is a continuous filament, polycrystalline a-alumina yarn designated Fibre FP. This fibre is suitable for reinforcing a variety of materials, especially non-ferrous metal castings because of a combination of properties such as high strength and modulus, stability at elevated temperatures, composite castability and potentially low cost. Fibre FP, essentially > 99 % a-Al 2 O 3 , is made by a novel continuous ceramic fibre process utilizing low cost textile fibre spinning technology and is produced as a yarn containing 210 filaments. The modulus of Fibre FP is 379 GPa (55 x 10 6 lbf in -2 ) with a tensile strength of 1380 MPa (200000 lbf in -2 ). The room temperature strength and modulus of the fibre are retained to about 1000 °C. Recently, higher strength FP fibres with a tensile strength of 2070 MPa (300000 lbf in -2 ) have been demonstrated on a laboratory scale.

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