scholarly journals TauG-Guidance Of Neonatal Vocalizing

2017 ◽  
Author(s):  
David N Lee ◽  
Mateo Obregon ◽  
Jonathan Delafield-Butt
Keyword(s):  
Experimental Evidence ◽  
High Precision ◽  
Temporal Pattern ◽  
Full Term ◽  
Theory Of Action ◽  
Mathematical Function ◽  
Term Neonates ◽  
Tau Theory ◽  
General Tau Theory ◽  
Human Neonates

AbstractA theory of action control (General Tau Theory) is applied to analyzing the vocalizations of human neonates. A central aspect of the theory, which is supported by experimental evidence across various actions and species, is that the trajectories of competent skilled actions follow a particular temporal pattern, which is described by the mathematical function, tauG. It was found that the acoustic waveform of vocalizations of healthy, full-term babies followed the tauG pattern with high precision. We conclude that healthy full-term neonates can be born with the ability to tauG-guide their vocalizations.

scholarly journals Improving tauG-control of action in PD

2017 ◽  
Author(s):  
Benjaman Schögler ◽  
Rachel Polokoff ◽  
Gert-Jan Pepping ◽  
Jon Perkins ◽  
David N Lee
Keyword(s):  
Nervous System ◽  
Movement Control ◽  
Theory Of Action ◽  
Body Sway ◽  
Mathematical Function ◽  
Abnormal Movements ◽  
Lateral Body ◽  
Before And After ◽  
Tau Theory ◽  
General Tau Theory

AbstractA theory of action control (General Tau Theory) is applied to analyzing normal and abnormal movements in PD; and to designing and testing the efficacy of a sonic aid for PD. A central aspect of the theory, which is supported by experimental evidence across a variety of actions and species, is that the trajectories of competent skilled actions follow a particular temporal pattern, which is described by the mathematical function, tauG. Since tauG-control of actions can be largely deficient in PD, we designed a device that generates whoop-like sounds, where the fundamental frequency of the sound follows the tauG pattern. Our hypothesis was that by listening to these sounds the nervous system of someone with PD might be helped subsequently to self-generate tauG patterns in their nervous system, which might facilitate movement control in different situations. Five adults with PD, and five age-matched controls, took part in the study. They each listened to the sounds under two conditions: (a) experimental - turning a handle for 5 minutes while the sounds were played (b) control - turning the handle without the sounds. Before and after each condition, the tauG-control of lateral body sway while standing was measured (without the sounds playing), using force-plates, on two tasks: (i) keeping the feet down, (ii) lifting the trailing foot. The number of participants out of five, who showed greater ratio improvement following practice with whoop sounds compared to without sounds, was, on each task, high for the PDs compared with the age-matched controls (4 vs 2 or 3). Thus, for the PDs, listening to the tauG whoop-like sounds while performing one action (handle turning) improved subsequent tauG-control on a different task (body-swaying).

Assessment of serum levels of vitamin B12 in full term neonates with indirect hyperbilirubinemia

2019 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Gamal Mohamed ◽  
Reem Abdel-Salam ◽  
Rabie Mortada
Keyword(s):  
Vitamin B12 ◽  
Serum Levels ◽  
Full Term ◽  
Term Neonates

Cord Blood Alkaline Phosphatase as a predictor of Neonatal Jaundice in full term neonates

2020 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Samah Esmail ◽  
Ali Abdo ◽  
Sherief Elgebaly ◽  
Marwa Mostafa
Keyword(s):  
Alkaline Phosphatase ◽  
Cord Blood ◽  
Neonatal Jaundice ◽  
Full Term ◽  
Term Neonates

scholarly journals Sufentanil Disposition and Pharmacokinetic Model-Based Dosage Regimen for Sufentanil in Ventilated Full-Term Neonates

Pharmacology ◽  
2021 ◽  
pp. 1-6
Author(s):  
Pavla Pokorná ◽  
Martin Šíma ◽  
Birgit Koch ◽  
Dick Tibboel ◽  
Ondřej Slanař
Keyword(s):  
Linear Regression ◽  
Dosage Regimen ◽  
Regression Models ◽  
Drug Disposition ◽  
Prospective Trial ◽  
Full Term ◽  
Pharmacokinetic Parameters ◽  
Therapeutic Drug ◽  
Linear Regression Models ◽  
Term Neonates

<b><i>Introduction:</i></b> Sufentanil is a potent synthetic opioid used for analgesia in neonates; however, data concerning drug disposition of sufentanil and dosage regimen are sparse in this population. Therefore, the aim of the study was to explore sufentanil disposition and to propose optimal loading and maintenance doses of sufentanil in ventilated full-term neonates. <b><i>Methods:</i></b> Individual sufentanil pharmacokinetic parameters were calculated based on therapeutic drug monitoring data using a 2-compartmental model. Linear regression models were used to explore the covariates. <b><i>Results:</i></b> The median (IQR) central volume of distribution (Vd<sub>c</sub>) and clearance (CL) for sufentanil were 4.7 (4.1–5.4) L/kg and 0.651 (0.433–0.751) L/h/kg, respectively. Linear regression models showed relationship between Vd<sub>c</sub> (L) and GA (<i>r</i><sup>2</sup> = 0.3436; <i>p</i> = 0.0452) as well as BW (<i>r</i><sup>2</sup> = 0.4019; <i>p</i> = 0.0268). Median optimal sufentanil LD and MD were 2.13 (95% CI: 1.78–2.48) μg/kg and 0.29 (95% CI: 0.22–0.37) μg/kg/h, respectively. Median daily COMFORT-B (IQR) scores ranged from 6 to 23 while no significant relationship between pharmacokinetic parameters and COMFORT-B scores was found. <b><i>Discussion/Conclusion:</i></b> Body weight and gestational age were found as weak covariates for sufentanil distribution, and the dosage regimen was developed for a prospective trial.

CXCR5‐CXCL13 axis markers in full‐term and preterm human neonates in the first weeks of life

2021 ◽  
Author(s):  
Carlo Pietrasanta ◽  
Pasqualina De Leo ◽  
Tatiana Jofra ◽  
Andrea Ronchi ◽  
Lorenza Pugni ◽  
...  
Keyword(s):  
Full Term ◽  
Human Neonates

The Hemodynamically Significant Ductus Arteriosus in Critically Ill Full-Term Neonates

Neonatology ◽  
2006 ◽  
Vol 91 (4) ◽  
pp. 260-265 ◽  
Author(s):  
Linh G. Ly ◽  
Judith Hawes ◽  
Hilary E. Whyte ◽  
Lilian S. Teixeira ◽  
Patrick J. McNamara
Keyword(s):  
Critically Ill ◽  
Ductus Arteriosus ◽  
Full Term ◽  
Term Neonates

Bifidobacterium longum and Bifidobacterium breve isolates from preterm and full term neonates: Comparison of cell surface properties

Anaerobe ◽  
2014 ◽  
Vol 28 ◽  
pp. 212-215 ◽  
Author(s):  
Valérie Andriantsoanirina ◽  
Anne-Claire Teolis ◽  
Liu Xin Xin ◽  
Marie Jose Butel ◽  
Julio Aires
Keyword(s):  
Cell Surface ◽  
Surface Properties ◽  
Bifidobacterium Longum ◽  
Full Term ◽  
Term Neonates ◽  
Bifidobacterium Breve ◽  
Cell Surface Properties

Magnetic Resonance Imaging Evaluation of Neonates With Retinal Hemorrhages

PEDIATRICS ◽  
1992 ◽  
Vol 89 (2) ◽  
pp. 332-333
Author(s):  
WILBUR L. SMITH ◽  
RANDELL C. ALEXANDER ◽  
G. FRANK JUDISCH ◽  
YUTAKA SATO ◽  
SIMON C. S. KAO
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Abusive Head Trauma ◽  
Full Term ◽  
Resonance Imaging ◽  
Retinal Hemorrhages ◽  
Imaging Evaluation ◽  
Term Neonates ◽  
Magnetic Resonance Imaging Evaluation ◽  
A Prospective Study

Retinal hemorrhages occur frequently in association with abusive head trauma.1 The injuries are venous [See table in the PDF] in origin and, as such, are similar to the retinal hemorrhages which frequently occur in full-term neonates after vaginal delivery. Because retinal hemorrhages in child abuse frequently are associated with intracranial bleeding, we questioned the possibility of a relationship between parturitional retinal hemorrhages and concurrent intracranial injuries. To answer this question we designed a prospective study in which we performed magnetic resonance imaging on 10 randomly selected full-term neonates in whom the presence of retinal hemorrhages was confirmed on fundascopic examination by a pediatric ophthalmologist.

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