scholarly journals Holsteins Favor Heifers, Not Bulls: Biased Milk Production Programmed during Pregnancy as a Function of Fetal Sex

2014 ◽  
Author(s):  
Katie Hinde ◽  
Abigail J Carpenter ◽  
John C Clay ◽  
Barry J Bradford

Mammalian females pay high energetic costs for reproduction, the greatest of which is imposed by lactation. The synthesis of milk requires, in part, the mobilization of bodily reserves to nourish developing young. Numerous hypotheses have been advanced to predict how mothers will differentially invest in sons and daughters, however few studies have addressed sex-biased milk synthesis. Here we leverage the dairy cow model to investigate such phenomena. Using 2.39 million lactation records from 1.49 million dairy cows, we demonstrate that the sex of the fetus influences the capacity of the mammary gland to synthesize milk during lactation. Cows favor daughters, producing significantly more milk for daughters than for sons across lactation. Using a sub-sample of this dataset (N=113,750 subjects) we further demonstrate that the effects of fetal sex interact dynamically across parities, whereby the sex of the fetus being gestated can enhance or diminish the production of milk during an established lactation. Moreover the sex of the fetus gestated on the first parity has persistent consequences for milk synthesis on the subsequent parity. Specifically, gestation of a daughter on the first parity increases milk production by ~445 kg over the first two lactations. Our results identify a dramatic and sustained programming of mammary function by offspring in utero. Nutritional and endocrine conditions in utero are known to have pronounced and long-term effects on progeny, but the ways in which the progeny has sustained physiological effects on the dam have received little attention to date.

Author(s):  
M.M. Abubakar ◽  
P. Rowlinson

The antibiotic Actaplanin is a complex of glycopeptide compounds produced by Actinoplanes missourrensis. When included in feed as a performance enhancer it has been shown to increase milk production of dairy cows (McGuffey et al. 1983). Actaplanin is associated with reduced proportions of acetate and increased proportions of propionate in rumen fluid and a depression in milk fat proportion may result (Clapperton et al. 1987). The aim of the trial reported here was to monitor the effects of feeding 960 mg Actaplanin/head/d to dairy cows throughout two successive lactations.


2019 ◽  
Vol 59 (8) ◽  
pp. 1510 ◽  
Author(s):  
V. M. Merino ◽  
O. A. Balocchi ◽  
R. G. Pulido

Daily herbage allowance is recognised as the main tool to control pasture utilisation and milk production per cow. The aim of the present study was to evaluate the long-term effects of daily herbage allowance (DHA) on pasture characteristics and milk production of dairy cows. Forty-four dairy cows were randomly assigned to one of four treatments in a 2 × 2 factorial design by considering two levels of DHA (20 and 30 kg DM/cow.day) and two types of supplements (high-moisture maize and maize silage) over a 77-day period. Pre- and post-grazing herbage masses, vertical distribution of herbage mass, species density, botanical and chemical composition, sward depletion and changes in morphological components of the pasture were measured. The effect of DHA on soil compaction was evaluated on the basis of the penetration resistance. Milk production and composition levels, bodyweights and body condition scores were recorded. Post-grazing residual declined as the level of DHA decreased, while grazing efficiency increased from 39.8% to 44.8%. We found no effects of DHA on any pasture characteristics, pasture regrowth or soil compaction. Low-DHA conditions induced a faster sward-height reduction, while the herbage mass remained unaffected. Individual milk production decreased with DHA. However, milk outputs per hectare increased by 2772 L/ha. Milk composition, bodyweight and body condition score were not affected by DHA. The results showed that DHA restriction decreases milk production per cow while increasing both herbage utilisation and milk production per hectare, without affecting long-term pasture condition.


2019 ◽  
Vol 102 (12) ◽  
pp. 11701-11717 ◽  
Author(s):  
M.R. Carvalho ◽  
F. Peñagaricano ◽  
J.E.P. Santos ◽  
T.J. DeVries ◽  
B.W. McBride ◽  
...  

2021 ◽  
Vol 9 (6) ◽  
pp. 1121
Author(s):  
Nathaly Cancino-Padilla ◽  
Natalia Catalán ◽  
Karen Siu-Ting ◽  
Christopher J. Creevey ◽  
Sharon A. Huws ◽  
...  

Dietary lipids increase energy density in dairy cow diets and in some cases can increase beneficial fatty acids (FA) in milk and dairy products. However, the degree of FA saturation may affect the rumen microbiome. The objective of this study was to determine the long-term effects of feeding saturated (hydrogenated vegetable oil; HVO) or unsaturated (olive oil; OO) fatty acid (FA) sources on the rumen microbiome of dairy cows. For 63 days, 15 mid-lactating cows were fed with either a basal diet (no fat supplement), or the basal diet supplemented with 3% dry matter (DM), either HVO or OO. Rumen contents were collected on days 21, 42 and 63 for 16S rRNA gene sequencing using the Illumina MiSeq platform. The results reveal dominance of the phyla Firmicutes (71.5%) and Bacteroidetes (26.2%), and their respective prevalent genera Succiniclasticum (19.4%) and Prevotella (16.6%). Succiniclasticum increased with both treatments at all time points. Prevotella was reduced on day 42 in both diets. Bacterial diversity alpha or beta were not affected by diets. Predicted bacterial functions by CowPI showed changes in energy and protein metabolism. Overall, 3% DM of lipid supplementation over 63 days can be used in dairy cow diets without major impacts on global bacterial community structure.


PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0206046 ◽  
Author(s):  
Amy L. Skibiel ◽  
Bethany Dado-Senn ◽  
Thiago F. Fabris ◽  
Geoffrey E. Dahl ◽  
Jimena Laporta

1989 ◽  
Vol 56 (4) ◽  
pp. 561-577 ◽  
Author(s):  
William H. Broster ◽  
A. June Clements ◽  
Valerie J. Broster ◽  
Tim Smith ◽  
Jonathan W. Siviter ◽  
...  

SummaryEighty-nine autumn-calving first calf and adult Friesian cows participated in an experiment on the effect of feeding over three lactations on milk production and live weight change. Fixed daily allowances of digestible energy (DE) formed two of the treatments (high, H; moderate, M). Diets of similar composition were used for both treatments and rations were weighed daily for each cow. The cows within these treatments were re-randomized to H or M at second and again at third parturition on experiment. A further treatment (ALF), applied continuously over three lactations, consisted of the M allowance of compound feed, weighed daily for each cow, plus ad lib. weighed, group-fed forages. The ALF animals were randomized for each lactation into two groups both of which received the same total compound feed allowance over the first 26 weeks of lactation. For one group (Flat) equal amounts were given daily whilst for the other group (Step) the daily amount was decreased monthly. After week 26 equal rations were fed. Hay, maize silage and grass silage formed the forages in winter. Grass, cut for the H and M groups but grazed for the ALF group, provided the summer forage. Energy intakes covered some 80–110% of requirements (Alderman et al. 1975)Yields of milk and of milk solids responded similarly for both parities. In the first experimental lactation, treatment H led to greater yields compared with M. H also led to smaller losses of live weight in early lactation, equal gains in mid lactation, and smaller gains in late lactation and the dry period, compared with M. Extension of H into a second lactation increased the advantage in milk and solids yields observed in the first lactation on experiment. Recovery of body reserves on treatment M continued. Treatment H in a second lactation on experiment after M in the first lactation led to even greater compensatory gains in live weight at the expense of milk production. There was no effect in the third lactation on experiment of treatments applied in the first lactation. Treatments H and M applied factorially over lactations 2 and 3 gave the same pattern of treatment effects as in lactations 1 and 2. Treatment ALF broadly supported the same milk yield and live weight change as treatment H but improved fat, protein and lactose yields. Within treatment ALF, Flat and Step distribution of compound led to equal performance. Multiple lactation effects of ALF equalled those of H. The effects on milk composition of H compared with M treatment were variable. In general an advantage accrued to ALF over M but without long term effects.The effect of variation in intake on performance of the dairy cow has been extensively documented for short periods within lactations (Broster, 1972), and more so for milk production than live weight change. However, the evidence on the size and development of effects of variation in feeding over protracted periods within the adult life span of the dairy cow, e.g. some four lactations in the UK, is extremely limited (Broster & Broster, 1984; Broster et al. 1984), both for plane of nutrition and for diet composition. The problem has added point with the introduction of simplified feeding systems which lead to the provision of less attention to the individual cow than hitherto (Johnson, 1982; Leaver, 1986). This dearth of information on the long term feeding of the adult contrasts with the widely gathered evidence on the effect of feeding during rearing on the performance of the mature cow, which is also an important long term relationship. More multi-lactation research is needed and in the present trial, with both young and adult lactating cows, the effects of amount and composition of feed allowance over three lactations were studied.


2012 ◽  
Vol 141 (3-4) ◽  
pp. 117-129 ◽  
Author(s):  
Kathrin Wagner ◽  
Kerstin Barth ◽  
Rupert Palme ◽  
Andreas Futschik ◽  
Susanne Waiblinger
Keyword(s):  

The Lancet ◽  
2000 ◽  
Vol 356 (9231) ◽  
pp. 696 ◽  
Author(s):  
Dimitrios Trichopoulos

2007 ◽  
Vol 87 (4) ◽  
pp. 639-646 ◽  
Author(s):  
N. E. Odongo ◽  
D. McKnight ◽  
A. KoekKoek ◽  
J. W. Fisher ◽  
P. Sharpe ◽  
...  

The objective of this study was to assess the long-term effects of feeding a diet with no mineral phosphorus (P) supplementation on performance and P excretion in high-yielding dairy cows. In exp. 1, 24 primiparous (PP) and 40 multiparous (MP) Holstein cows were allocated to one of two treatments at calving: (1) regular corn silage and alfalfa haylage based milking cow total mixed ration (TMR; 0.42% P diet) or (2) milking cow total mixed ration (TMR) without supplemental mineral P (0.35% P diet) in a completely randomized design. The trial lasted until after two lactations were completed or the cow was culled. In exp. 2, eight MP Holstein cows (108 ± 8.0 d in milk) were used to determine P digestibility and retention in a completely randomized block design. In exp. 1, the 0.35% P diet cows had lower body weight, body condition score and milk urea nitrogen and higher faecal P than the 0.42% P cows. The dry matter intake (DMI) of PP cows on the 0.35% P diet was lower than that of PP cows on the 0.42% P diet. There was no difference in the DMI of MP cows. The P intake of 0.35% P diet PP cows was 30% lower than that of 0.42% P diet PP cows. The P intake of 0.35% P diet MP cows was 20% lower than that of 0.42% P diet MP. The digestibility coefficient of P for the 0.35% P diet was higher than that for the 0.42% P diet. These results suggest that the forages used in the present study contained adequate amounts of P to sustain milk production in high-yielding MP cows. However, for PP cows some mineral P supplementation is recommended especially during early lactation. Key words: Phosphorus, environmental pollution, intensive dairy operations


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