scholarly journals Involvement of theGli3 (Extra-Toes)Gene Region in Body Weight in Mice

2007 ◽  
Vol 7 ◽  
pp. 83-86 ◽  
Author(s):  
Benoît Martin ◽  
Eve Lapouble ◽  
Yohan Chaix

The mutation extra-toes (Gli3Xt-J) on chromosome (Chr) 13 of the mouse is known to be involved in the development of the skeleton. The only visible manifestation is the presence of an extra digit on each hind foot. Here we report evidence from several experiments that Gli3XtJ/+mice weigh more than littermate Gli3+/+mice, suggesting an effect on body weight ofGli3or of a gene tightly linked to it on Chr 13. Four independent experiments in different environments were conducted on mice with different genetic backgrounds derived from the C3XtEso Gli3Xt-J/+Eso/+linkage testing strain and the JE/Le strain at adult age. The analyses have shown an association between the Gli3Xt-Jallele and a body weight increase of about 6.5%. This effect is genetically dominant. It would appear that if the gene of interest is notGli3itself, it must be very close to this locus. Indeed, the expected size for this fragment is 7.9 ± 5.3 cM. The manifestation of this gene, observed in two animal facilities and on different genetic backgrounds, is consistent with the idea that the effect of the gene(s) is displayed in a stable manner. It accounts for a variation of 6.5% of body weight.

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 930
Author(s):  
Odysseas Androutsos ◽  
Maria Perperidi ◽  
Christos Georgiou ◽  
Giorgos Chouliaras

Previous studies showed that the coronavirus disease 2019 (COVID-19) lockdown imposed changes in adults’ lifestyle behaviors; however, there is limited information regarding the effects on youth. The COV-EAT study aimed to report changes in children’s and adolescents’ lifestyle habits during the first COVID-19 lockdown and explore potential associations between changes of participants’ lifestyle behaviors and body weight. An online survey among 397 children/adolescents and their parents across 63 municipalities in Greece was conducted in April–May 2020. Parents self-reported changes of their children’s lifestyle habits and body weight, as well as sociodemographic data of their family. The present study shows that during the lockdown, children’s/adolescents’ sleep duration and screen time increased, while their physical activity decreased. Their consumption of fruits and fresh fruit juices, vegetables, dairy products, pasta, sweets, total snacks, and breakfast increased, while fast-food consumption decreased. Body weight increased in 35% of children/adolescents. A multiple regression analysis showed that the body weight increase was associated with increased consumption of breakfast, salty snacks, and total snacks and with decreased physical activity. The COV-EAT study revealed changes in children’s and adolescents’ lifestyle behaviors during the first COVID-19 lockdown in Greece. Effective strategies are needed to prevent excessive body weight gain in future COVID-19 lockdowns.


Author(s):  
Daniela Reyes-Olavarría ◽  
Pedro Ángel Latorre-Román ◽  
Iris Paola Guzmán-Guzmán ◽  
Daniel Jerez-Mayorga ◽  
Felipe Caamaño-Navarrete ◽  
...  

The association between the changes in lifestyle during coronavirus disease 2019 (COVID-19) confinement and body weight have not been studied deeply. Therefore, the aim of the present study was to determine lifestyle changes, such as eating habits and physical activity (PA) patterns, caused by confinement during the COVID-19 pandemic and to analyze its association with changes in body weight. Seven hundred participants (women, n = 528 and men, n = 172) aged between 18–62 years old of the Chilean national territory participated in the study. Food habits, PA, body weight, and sociodemographic variables were measured through a survey in May and June 2020. The body weight increase presented positive association with the consumption of fried foods ≥ 3 times per week (OR; 3.36, p < 0.001), low water consumption (OR; 1.58, p = 0.03), and sedentary time ≥6 h/day (OR; 1.85, p = 0.01). Conversely, fish consumed (OR; 0.67, p = 0.03), active breaks (OR; 0.72, p = 0.04), and PA ≥ 4 times per week (OR; 0.51, p = 0.001) presented an inverse association with body weight increase. Daily alcohol consumption (OR; 4.77, p = 0.003) was associated with PA decrease. Food habits, PA, and active breaks may be protective factors for weight increase during COVID-19 confinement.


1957 ◽  
Vol 35 (1) ◽  
pp. 1113-1118
Author(s):  
George H. Beaton ◽  
Hannah Z. Banky ◽  
Audrey M. Haufschild

Doses of growth hormone which were minimal with respect to body weight increase were sufficient to produce significant alterations in liver alanine – glutamic transaminase and arginase activities and blood urea and amino nitrogen levels. The biochemical effects of the hormone appeared coincident with the body weight increase. Female rats showed a more pronounced response to growth hormone than did male rats. This sex difference was evident with respect to all of the metabolic alterations observed. Although it is not possible to state whether the metabolic alterations are direct effects of the hormone, they do take an integral part in bringing about the over-all biological effect.


1982 ◽  
Vol 99 (2) ◽  
pp. 355-358 ◽  
Author(s):  
G. D. Braithwaite

SUMMARYA re-examination of the results from 374 sheep used in previovis studies of calcium metabolism show there is a highly significant linear relationship between endogenous faecal loss of Oa and food intake, endogenous loss increasing by about 0·64 mg/day/kg body weight for each 1 g/day/kg body weight increase in food intake. This loss was unaltered by Ca intake or by pregnancy and lactation but was slightly higher in young animals than in adult animals given the same Ca intake on a body-weight basis. It is suggested that a variable factor for endogenous Ca loss, based upon some measure of level of feeding, should be introduced into rationing schemes.


2013 ◽  
Vol 60 (6) ◽  
pp. 303-307 ◽  
Author(s):  
Eduardo Alejandro Mormandi ◽  
Patricia Otero ◽  
Ana Laura Bertone ◽  
Mariela Calvo ◽  
Graciela Astarita ◽  
...  

2020 ◽  
Vol 45 (2) ◽  
pp. 16-20
Author(s):  
J. O. Egahi ◽  
O. M. Momoh ◽  
F. B. P. Abang

The normal feathered (NF), frizzle feathered (FF) and naked neck (Na) native chickens of Nigeria were outcrossed under the savanna ecology. Eggs were collected and artificially incubated in electric type incubator. Chicks were weighed at hatch, identified and raised on a standard compounded ration. Body weight increase was evaluated at 4-20 weeks of age. Heterosis was evaluated for hatch weight and body weight at 20 weeks of age. Results revealed that percent heterosis ranged from -12.11to 1.66 and 1.93 to 12.80 for hatch weight and body weight at 20 weeks of age, respectively. The outcrosses using the NF as males had a higher body weight at 20 weeks of age. Consequently, the environmental limitation on growth impinged more on the NF than on the FF and Na genotypes. It was also noted that there is a greater divergence between the NF and the FF, the NF and Na than between the FF and Na birds. Outcrossing the NF birds with the FF and Na birds in the savanna may therefore improve body weight at 20 weeks of age in the outcrosses than in the respective straight bred genotypes.


Author(s):  
Asit Chakrabarti ◽  
Pradip Kumar Sarkar ◽  
P.R. Kumar ◽  
V.K. Yadav ◽  
S.K. Naik ◽  
...  

Background: In view of abundant availability of Spilanthes paniculata in flora of Jharkhand and widely reported benefits of its dried flowers, the current study aimed to explore the possibility and to quantify the effect of use of flowers of S. paniculata as feed additives in stimulating body growth in poultry birds. Methods: A four week experiment consisting of 60 numbers of poultry birds (Divyan Red) of five months old subjected to four treatments consisting of 15 birds in each treatment distributed equally with 5 replications, was undertaken during 2016-19 following randomized block design to observe the effect of feeding dried flowers of S. paniculata on body weight increase in poultry birds. Result: Feeding of dried flowers of S. paniculata @ 10 g/bird/day resulted in a gradual increase in rate of weight gain up to 14 days of feeding, whereas feeding @ 15 g and 20 g/bird/day resulted in increase in body weight gain up to 7 days. Feeding @ 10 g/bird/day resulted in highest body weight increase after feeding for four weeks and improved in the feed conversion ratio (FCR) significantly (P ˂ 0.05) than the other 3 treatments. It is advisable for poultry owners to incorporate dried flowers of S. paniculata at a dose of 10 grams per bird per day for three weeks for attaining maximum growth in body weight in poultry birds.


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