scholarly journals Titanium-containing bioactive phosphate glasses

2012 ◽  
Vol 370 (1963) ◽  
pp. 1352-1375 ◽  
Author(s):  
A. Kiani ◽  
N. J. Lakhkar ◽  
V. Salih ◽  
M. E. Smith ◽  
J. V. Hanna ◽  
...  
Keyword(s):  
Physical Properties ◽  
Tissue Regeneration ◽  
Biomedical Applications ◽  
Review Paper ◽  
Phosphate Glasses ◽  
Bone Substitute Material ◽  
Soft Tissue Regeneration ◽  
Recent Developments ◽  
Titanium Incorporation ◽  
Biomedical Field

The use of biomaterials has revolutionized the biomedical field and has received substantial attention in the last two decades. Among the various types of biomaterials, phosphate glasses have generated great interest on account of their remarkable bioactivity and favourable physical properties for various biomedical applications relating to both hard and soft tissue regeneration. This review paper focuses mainly on the development of titanium-containing phosphate-based glasses and presents an overview of the structural and physical properties. The effect of titanium incorporation on the glassy network is to introduce favourable properties. The biocompatibility of these glasses is described along with recent developments in processing methodologies, and the potential of Ti-containing phosphate-based glasses as a bone substitute material is explored.

scholarly journals Polysaccharide-Based Aerogel Production for Biomedical Applications: A Comparative Review

Materials ◽  
2021 ◽  
Vol 14 (7) ◽  
pp. 1631
Author(s):  
Mariangela Guastaferro ◽  
Ernesto Reverchon ◽  
Lucia Baldino
Keyword(s):  
Tissue Regeneration ◽  
Supercritical Co2 ◽  
Biomedical Applications ◽  
Freeze Drying ◽  
Time Interval ◽  
Comparative Review ◽  
Biomedical Field ◽  
Low Cytotoxicity ◽  
Gel Preparation ◽  
Cell Adhesion And Proliferation

A comparative analysis concerning bio-based gels production, to be used for tissue regeneration, has been performed in this review. These gels are generally applied as scaffolds in the biomedical field, thanks to their morphology, low cytotoxicity, and high biocompatibility. Focusing on the time interval 2015–2020, the production of 3D scaffolds of alginate, chitosan and agarose, for skin and bone regeneration, has mainly been investigated. Traditional techniques are critically reviewed to understand their limitations and how supercritical CO2-assisted processes could overcome these drawbacks. In particular, even if freeze-drying represents the most widespread drying technique used to produce polysaccharide-based cryogels, supercritical CO2-assisted drying effectively allows preservation of the nanoporous aerogel structure and removes the organic solvent used for gel preparation. These characteristics are essential for cell adhesion and proliferation.

scholarly journals Current Research on Polyelectrolyte Nanostructures: From Molecular Interactions to Biomedical Applications

Macromol ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 155-172
Author(s):  
Aristeidis Papagiannopoulos
Keyword(s):  
Physical Properties ◽  
Molecular Interactions ◽  
Interdisciplinary Research ◽  
Biomedical Applications ◽  
Electrostatic Interactions ◽  
Soft Matter ◽  
Extracellular Polysaccharides ◽  
Polymer Science ◽  
Biological Matter ◽  
Biomedical Field

Polyelectrolytes have been at the center of interdisciplinary research for many decades. In the field of polymer science and soft matter, they have provided the dimensions of electrostatic interactions, which opens a vast variety of opportunities for new physical properties and applications. In biological matter, polyelectrolytes are present in many forms, from extracellular polysaccharides to complex DNA molecules and proteins. This review discusses the recent research on polyelectrolytes covering the fundamental level of their conformations and nanostructures, their molecular interactions with materials that have close relevance to bioapplications and their applications in the biomedical field. This approach is motivated by the fact that the polyelectrolyte research is constantly active in all the aforementioned levels and continually affects many critical scientific areas.

scholarly journals Applications of magnetic and multiferroic core/shell nanostructures and their physical properties

DYNA ◽  
2018 ◽  
Vol 85 (207) ◽  
pp. 29-35
Author(s):  
Claudia Milena Bedoya-Hincapié ◽  
Elisabeth Restrepo-Parra ◽  
Luis Demetrio López-Carreño
Keyword(s):  
Physical Properties ◽  
Biomedical Applications ◽  
Magnetic Behavior ◽  
Core Shell ◽  
Cellular Functions ◽  
Shell Nanostructures ◽  
Biomedical Field ◽  
Core Shell Structure ◽  
Significant Attention ◽  
Stimulation Of

The potential of nanotechnology in the biomedical field has been crucial for contributing to the possibility of efficiently meeting present necessities with novel materials. Over the last few decades, nanostructures with a core/shell structure have attracted significant attention because of the possibility of changing their physical properties by varying their chemistry and geometry. These structures have become relevant in targeted therapy (drug delivery and treatments to complement chemotherapy and radiotherapy), imaging and in the stimulation of cellular functions. Thus in this paper the current development of core/shell nanostructures is reviewed, emphasizing the physical properties of those that have been proposed as potentially having biomedical applications, which are based in a magnetic behavior or in a mixture of magnetic and electric (multiferroic) phenomena.

scholarly journals Virus-Based Nanomaterials and Nanostructures

Nanomaterials ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 567
Author(s):  
Jin-Woo Oh ◽  
Dong-Wook Han
Keyword(s):  
Energy Harvesting ◽  
Tissue Regeneration ◽  
Biomedical Applications ◽  
Special Issue ◽  
Future Directions ◽  
Biomimetic Materials ◽  
Recent Developments ◽  
Energy Harvesting Devices

This Special Issue highlights the recent developments and future directions of virus-based nanomaterials and nanostructures in energy and biomedical applications. The virus-based biomimetic materials formulated using innovative ideas presented herein are characterized for the applications of biosensors and nanocarriers. The research contributions and trends based on virus-based materials, covering energy-harvesting devices to tissue regeneration over the last two decades, are described and discussed.

scholarly journals Development of Nontoxic Biodegradable Polyurethanes Based on Polyhydroxyalkanoate and L-lysine Diisocyanate with Improved Mechanical Properties as New Elastomers Scaffolds

Polymers ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 1927 ◽  
Author(s):  
Cai Wang ◽  
Jiapeng Xie ◽  
Xuan Xiao ◽  
Shaojun Chen ◽  
Yiping Wang
Keyword(s):  
Tissue Regeneration ◽  
Biomedical Applications ◽  
Poly Ethylene Glycol ◽  
In Vitro Degradation ◽  
Elongation At Break ◽  
Molar Ratios ◽  
Soft Tissue Regeneration ◽  
Biodegradable Polyurethane ◽  
Poly Ethylene

A nontoxic and biodegradable polyurethane was prepared, characterized, and evaluated for biomedical applications. Stretchable, biodegradable, and biocompatible polyurethanes (LPH) based on L-lysine diisocyanate (LDI) with poly(ethylene glycol) (PEG) and polyhydroxyalkanoates(PHA) of different molar ratios were synthesized. The chemical and physical characteristics of the LPH films are tunable, enabling the design of mechanically performance, hydrophilic, and biodegradable behavior. The LPH films have a Young’s modulus, tensile strength, and elongation at break in the range of 3.07–25.61 MPa, 1.01–9.49 MPa, and 102–998%, respectively. The LPH films demonstrate different responses to a change of temperature from 4 to 37 °C, with the swelling ratio for the same sample at equilibrium varying from 184% to 151%. In vitro degradation tests show the same LPH film has completely different degradation morphologies in pH of 3, 7.4, and 11 phosphate buffered solution (PBS). In vitro cell tests show feasibility that some of the LPH films are suitable for culturing rat bone marrow stem cells (rBMSCs), for future soft-tissue regeneration. The results demonstrate the feasibility of the LPH scaffolds for many biomedical applications.

Recent developments in the synthesis, properties, and biomedical applications of core/shell superparamagnetic iron oxide nanoparticles with gold

2017 ◽  
Vol 5 (11) ◽  
pp. 2212-2225 ◽  
Author(s):  
Sandip Sabale ◽  
Priyanka Kandesar ◽  
Vidhya Jadhav ◽  
Rachel Komorek ◽  
Radha Kishan Motkuri ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Core Shell ◽  
Synthesis Properties ◽  
Recent Developments ◽  
Biomedical Field

In the last decade, Gold (Au) coated superparamagnetic iron oxide nanoparticles (SPIONs), have immensely promoted the advancement of diagnostics and theranostics in the biomedical field.

Hyaluronic Acid Fillers in Soft Tissue Regeneration

2017 ◽  
Vol 33 (01) ◽  
pp. 087-096 ◽  
Author(s):  
Arianna Fallacara ◽  
Elisa Durini ◽  
Silvia Vertuani ◽  
Stefano Manfredini
Keyword(s):  
Hyaluronic Acid ◽  
Soft Tissue ◽  
Physical Properties ◽  
Tissue Regeneration ◽  
The Other ◽  
Dermal Fillers ◽  
General Introduction ◽  
Soft Tissue Regeneration ◽  
Cross Linkage ◽  
Unique Chemical

AbstractOver the last years, hyaluronic acid (HA) injectable dermal fillers (DFs) have become the most popular agents for soft tissue contouring and volumizing. HA fillers are characterized by most of the properties that an ideal DF should have, due to HA unique chemical-physical properties, biocompatibility, biodegradability, and versatility. Therefore, HA DFs have revolutionized the filler market with a high number of products, which differ in terms of HA source, cross-linkage (agent and degree), HA concentration, hardness, cohesivity, consistency, inclusion or lack of anesthetic, indication, and longevity of correction. The article first provides a general introduction to DF world, and an overview of the different materials is available for fillers. Second, it describes the characteristics and the peculiarities of HA fillers, their differences from the other available materials, and therefore the reasons at the base of their success. Moreover, an update regarding the main Food and Drug Administration (FDA) approved fillers is presented.

Bacterial Nanocellulose as a Renewable Material for Biomedical Applications

MRS Bulletin ◽  
2010 ◽  
Vol 35 (3) ◽  
pp. 208-213 ◽  
Author(s):  
Paul Gatenholm ◽  
Dieter Klemm
Keyword(s):  
Tissue Regeneration ◽  
Biomedical Applications ◽  
Foreign Body Reaction ◽  
Cell Immobilization ◽  
Gluconacetobacter Xylinus ◽  
Bacterial Nanocellulose ◽  
Renewable Material ◽  
Biomedical Field ◽  
Water Holding ◽  
Cell Support

AbstractNanocellulose, such as that produced by the bacteria Gluconacetobacter xylinus (bacterial cellulose, BC), is an emerging biomaterial with great potential as a biological implant, wound and burn dressing material, and scaffolds for tissue regeneration. BC has remarkable mechanical properties despite the fact that it contains up to 99% water. The water-holding ability is the most probable reason why BC implants do not elicit any foreign body reaction. Moreover, the nanostructure and morphological similarities with collagen make BC attractive for cell immobilization and cell support. The architecture of BC materials can be engineered over length scales ranging from nano to macro by controlling the biofabrication process. This article describes current and future applications of BC in the biomedical field.

scholarly journals Differential GFR estimation of the double moiety kidneys by modified GATE’S formula

2021 ◽  
Vol 3 (3) ◽  
pp. 01-07
Author(s):  
Sivasubramaniyan V
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Physical Properties ◽  
Tissue Regeneration ◽  
Biomedical Applications ◽  
Living Cells ◽  
Advanced Imaging ◽  
Wide Range ◽  
Gfr Estimation ◽  
Or Gene

Since the beginning of the twenty-one century, carbon based nanomaterial (CNTs) has been introduced in (pharmacy and medicine) in therapeutic for system of drug delivery. NTs have proved able to transport a wide range of molecules across membranes and into living cells; therefore, they have attracted great interest in biomedical applications such as advanced imaging, tissue regeneration, and drug or gene deliver. As it is known, carbon nanotubes exhibit various unique intrinsic chemical and physical properties and it has been intensive explored, in the last few years, for applications in biology and biomedicine.

scholarly journals Self-Assembling Peptides: From Design to Biomedical Applications

2021 ◽  
Vol 22 (23) ◽  
pp. 12662
Author(s):  
Sara La Manna ◽  
Concetta Di Natale ◽  
Valentina Onesto ◽  
Daniela Marasco
Keyword(s):  
Drug Delivery ◽  
Tissue Regeneration ◽  
Biomedical Applications ◽  
Biological Functions ◽  
Stimuli Responsive ◽  
Hydrophilic Drugs ◽  
Self Assembling ◽  
Recognition Sites ◽  
Biomedical Field ◽  
Self Assembled

Self-assembling peptides could be considered a novel class of agents able to harvest an array of micro/nanostructures that are highly attractive in the biomedical field. By modifying their amino acid composition, it is possible to mime several biological functions; when assembled in micro/nanostructures, they can be used for a variety of purposes such as tissue regeneration and engineering or drug delivery to improve drug release and/or stability and to reduce side effects. Other significant advantages of self-assembled peptides involve their biocompatibility and their ability to efficiently target molecular recognition sites. Due to their intrinsic characteristics, self-assembled peptide micro/nanostructures are capable to load both hydrophobic and hydrophilic drugs, and they are suitable to achieve a triggered drug delivery at disease sites by inserting in their structure’s stimuli-responsive moieties. The focus of this review was to summarize the most recent and significant studies on self-assembled peptides with an emphasis on their application in the biomedical field.

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