scholarly journals Evolutionary dynamics and molecular epidemiology of West Nile virus in New York State: 1999–2015

2019 ◽  
Vol 5 (2) ◽  
Author(s):  
Sean M Bialosuknia ◽  
Yi Tan ◽  
Steven D Zink ◽  
Cheri A Koetzner ◽  
Joseph G Maffei ◽  
...  
Keyword(s):  
New York ◽  
West Nile Virus ◽  
Molecular Epidemiology ◽  
Evolutionary Dynamics ◽  
New York State ◽  
West Nile ◽  
York State

scholarly journals Evolutionary dynamics and molecular epidemiology of West Nile virus in New York State: 1999–2015

2019 ◽  
Vol 5 (2) ◽  
Author(s):  
Sean M Bialosuknia ◽  
Yi Tan ◽  
Steven D Zink ◽  
Cheri A Koetzner ◽  
Joseph G Maffei ◽  
...  
Keyword(s):  
New York ◽  
West Nile Virus ◽  
Deep Sequencing ◽  
Evolutionary Dynamics ◽  
New York State ◽  
Rapid Expansion ◽  
Sequencing Data ◽  
West Nile ◽  
York State ◽  
Deep Sequencing Data

AbstractFollowing its introduction into New York State (NYS) in 1999, West Nile virus (WNV; Flavivirus, Flaviviridae) underwent a rapid expansion throughout the USA and into Canada and Latin America. WNV has been characterized as being evolutionarily stable, with weak geographic structure, a dominance of purifying selection and limited adaptive change. We analyzed all available full-genome WNV sequences, focusing on the 543 available sequences from NYS, which included 495 newly sequenced 2000–15 isolates. In addition, we analyzed deep-sequencing data from 317 of these isolates. While our data are generally in agreement with the limited pace of evolutionary change and broad geographic and temporal mixing identified in other studies, we have identified some important exceptions. Most notably, there are 14 codons which demonstrated evidence of positive selection as determined by multiple models, including some positions with evidence of selection in NYS exclusively. Coincident with increased WNV activity, genotypes possessing one or more of these mutations, designated NY01, NY07, and NY10, have increased in prevalence in recent years and displaced historic strains. In addition, we have found a geographical bias with many of these mutations, which suggests selective pressures and adaptations could be regional. Lastly, our deep-sequencing data suggest both increased overall diversity in avian tissue isolates relative to mosquito isolates and multiple non-synonymous minority variants that are both host-specific and retained over time and space. Together, these data provide novel insight into the evolutionary pressures on WNV and the need for continued genetic surveillance and characterization of emergent strains.

scholarly journals Mosquito Surveillance and Polymerase Chain Reaction Detection of West Nile Virus, New York State

2001 ◽  
Vol 7 (4) ◽  
pp. 643-649 ◽  
Author(s):  
Dennis J. White ◽  
Laura D. Kramer ◽  
P. Bryon Backenson ◽  
Gary Lukacik ◽  
Geraldine Johnson ◽  
...  
Keyword(s):  
New York ◽  
Polymerase Chain Reaction ◽  
West Nile Virus ◽  
New York State ◽  
Polymerase Chain Reaction Detection ◽  
Chain Reaction ◽  
West Nile ◽  
Mosquito Surveillance ◽  
York State ◽  
Polymerase Chain

scholarly journals Factors Associated With the Risk of West Nile Virus Among Crows in New York State

2010 ◽  
Vol 58 (4) ◽  
pp. 270-275 ◽  
Author(s):  
C. H. DeCarlo ◽  
A. B. Clark ◽  
K. J. McGowan ◽  
P. E. Ziegler ◽  
A. L. Glaser ◽  
...  
Keyword(s):  
New York ◽  
West Nile Virus ◽  
New York State ◽  
West Nile ◽  
York State ◽  
Factors Associated

scholarly journals West Nile Virus Outbreak Among Horses in New York State, 1999 and 2000

2001 ◽  
Vol 7 (4) ◽  
pp. 745-747 ◽  
Author(s):  
Susan C. Trock ◽  
Barry J. Meade ◽  
Amy L. Glaser ◽  
Eileen N. Ostlund ◽  
Robert S. Lanciotti ◽  
...  
Keyword(s):  
New York ◽  
West Nile Virus ◽  
New York State ◽  
West Nile ◽  
York State

scholarly journals Dead Crow Densities and Human Cases of West Nile Virus, New York State, 2000

2001 ◽  
Vol 7 (4) ◽  
pp. 662-664 ◽  
Author(s):  
Millicent Eidson ◽  
Jim Miller ◽  
Laura Kramer ◽  
Bryan Cherry ◽  
Yoichiro Hagiwara ◽  
...  
Keyword(s):  
New York ◽  
West Nile Virus ◽  
New York State ◽  
West Nile ◽  
York State

scholarly journals West Nile Virus Infection in Birds and Mosquitoes, New York State, 2000

2001 ◽  
Vol 7 (4) ◽  
pp. 679-685 ◽  
Author(s):  
Kristen A. Bernard ◽  
Joseph G. Maffei ◽  
Susan A. Jones ◽  
Elizabeth B. Kauffman ◽  
Gregory D. Ebel ◽  
...  
Keyword(s):  
New York ◽  
West Nile Virus ◽  
Virus Infection ◽  
New York State ◽  
West Nile Virus Infection ◽  
West Nile ◽  
York State

WEST NILE VIRUS SURVEILLANCE IN MOSQUITOES IN NEW YORK STATE, 2000–2004

2006 ◽  
Vol 22 (2) ◽  
pp. 264-271 ◽  
Author(s):  
GARY LUKACIK ◽  
MADHU ANAND ◽  
EMILY J. SHUSAS ◽  
JOHN J. HOWARD ◽  
JOANNE OLIVER ◽  
...  
Keyword(s):  
New York ◽  
West Nile Virus ◽  
New York State ◽  
West Nile ◽  
York State ◽  
Virus Surveillance

scholarly journals Geographic Prediction of Human Onset of West Nile Virus Using Dead Crow Clusters: An Evaluation of Year 2002 Data in New York State

2005 ◽  
Vol 163 (2) ◽  
pp. 171-180 ◽  
Author(s):  
Glen D. Johnson ◽  
Millicent Eidson ◽  
Kathryn Schmit ◽  
April Ellis ◽  
Martin Kulldorff
Keyword(s):  
New York ◽  
West Nile Virus ◽  
New York State ◽  
West Nile ◽  
York State
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