scholarly journals The Spectrum of Circulating RNA: A Window into Systems Toxicology

2013 ◽  
Vol 132 (2) ◽  
pp. 478-492 ◽  
Author(s):  
Kai Wang ◽  
Yue Yuan ◽  
Hong Li ◽  
Ji-Hoon Cho ◽  
David Huang ◽  
...  
Keyword(s):  
Systems Toxicology ◽  
Circulating Rna

Systems Toxicology: Systematic Approach to Predict Toxicity

2017 ◽  
Vol 22 (46) ◽  
pp. 6911-6917 ◽  
Author(s):  
Narsis Kiani ◽  
Ming-Mei Shang ◽  
Jesper Tegner
Keyword(s):  
Systematic Approach ◽  
Systems Toxicology

Circulating RNA differences between patients with stable and progressive idiopathic pulmonary fibrosis

2020 ◽  
Vol 56 (3) ◽  
pp. 1902058
Author(s):  
Britt Clynick ◽  
Helen E. Jo ◽  
Tamera J. Corte ◽  
Ian N. Glaspole ◽  
Christopher Grainge ◽  
...  
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Circulating Rna

scholarly journals Systems Toxicology Approach for Testing Chemical Cardiotoxicity in Larval Zebrafish

2020 ◽  
Vol 33 (10) ◽  
pp. 2550-2564 ◽  
Author(s):  
Roman Li ◽  
Anze Zupanic ◽  
Marja Talikka ◽  
Vincenzo Belcastro ◽  
Sumit Madan ◽  
...  
Keyword(s):  
Systems Toxicology ◽  
Larval Zebrafish

Circulating RNA as a novel tumor marker: An in vitro study of the origins and characteristics of extracellular RNA

2008 ◽  
Vol 259 (1) ◽  
pp. 50-60 ◽  
Author(s):  
Hongxing Zhou ◽  
Wenrong Xu ◽  
Hui Qian ◽  
Qin Yin ◽  
Wei Zhu ◽  
...  
Keyword(s):  
Tumor Marker ◽  
In Vitro Study ◽  
Vitro Study ◽  
Extracellular Rna ◽  
Circulating Rna

scholarly journals Circulating RNA in blood plasma as diagnostic tool for clinical oncology

2020 ◽  
pp. 5-10
Author(s):  
EA Lolomadze ◽  
VV Kometova ◽  
VV Rodionov
Keyword(s):  
Blood Plasma ◽  
Tumor Cells ◽  
Diagnostic Technique ◽  
Circulating Tumor Dna ◽  
Malignant Neoplasms ◽  
Altered Gene Expression ◽  
Early Predictors ◽  
Altered Gene ◽  
Circulating Rna ◽  
Active Proliferation

One of the key challenges facing today’s oncology is the discovery of early predictors of malignant neoplasms in patients’ biological samples. Liquid biopsy is a noninvasive diagnostic technique based on the detection and isolation of tumor cells, tumor-derived nucleic acid and exosomes circulating in the blood plasma of cancer patients. There is a plethora of research studies of circulating tumor DNA in patients with MN. The active proliferation of tumor cells occurs in the backdrop of altered gene expression. The presence of tissue-specific transcripts in the circulating RNA fraction suggests that levels of circulating RNA reflect the development of the primary tumor. We think that cell-free RNA circulating in the blood plasma is a promising molecular biomarker for early cancer detection.

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