Application of an Updated Physiologically Based Pharmacokinetic Model for Chloroform to Evaluate CYP2E1-Mediated Renal Toxicity in Rats and Mice

Alan F. Sasso; Paul M. Schlosser; Gregory L. Kedderis; Mary Beth Genter; John E. Snawder; Zheng Li; Susan Rieth; John C. Lipscomb

doi:10.1093/toxsci/kfs320

Application of an Updated Physiologically Based Pharmacokinetic Model for Chloroform to Evaluate CYP2E1-Mediated Renal Toxicity in Rats and Mice

Toxicological Sciences ◽

10.1093/toxsci/kfs320 ◽

2012 ◽

Vol 131 (2) ◽

pp. 360-374 ◽

Cited By ~ 18

Author(s):

Alan F. Sasso ◽

Paul M. Schlosser ◽

Gregory L. Kedderis ◽

Mary Beth Genter ◽

John E. Snawder ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Renal Toxicity ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Rats And Mice

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Development of a Physiologically Based Pharmacokinetic Model to Describe the Disposition of Methanol in Pregnant Rats and Mice

Toxicology and Applied Pharmacology ◽

10.1006/taap.1997.8170 ◽

1997 ◽

Vol 145 (2) ◽

pp. 311-322 ◽

Cited By ~ 25

Author(s):

Keith W. Ward ◽

Gregory M. Blumenthal ◽

Frank Welsch ◽

Gary M. Pollack

Keyword(s):

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Pregnant Rats ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Rats And Mice

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A Physiologically Based Pharmacokinetic Model for Inhalation and Intravenous Administration of Naphthalene in Rats and Mice

Toxicology and Applied Pharmacology ◽

10.1006/taap.2001.9269 ◽

2001 ◽

Vol 176 (2) ◽

pp. 81-91 ◽

Cited By ~ 20

Author(s):

B.A.T. Willems ◽

R.L. Melnick ◽

M.C. Kohn ◽

C.J. Portier

Keyword(s):

Intravenous Administration ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Rats And Mice

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Corrigendum to “Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium” [Chem Biol Interact 2012;200:45–64]

Chemico-Biological Interactions ◽

10.1016/j.cbi.2013.06.002 ◽

2013 ◽

Vol 204 (3) ◽

pp. 201-206 ◽

Cited By ~ 1

Author(s):

C.R. Kirman ◽

S.M. Hays ◽

L.L. Aylward ◽

M. Suh ◽

M.A. Harris ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Rats And Mice

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Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium

Chemico-Biological Interactions ◽

10.1016/j.cbi.2012.08.016 ◽

2012 ◽

Vol 200 (1) ◽

pp. 45-64 ◽

Cited By ~ 33

Author(s):

C.R. Kirman ◽

S.M. Hays ◽

L.L. Aylward ◽

M. Suh ◽

M.A. Harris ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Rats And Mice

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Use of In Vitro Data for Construction of a Physiologically Based Pharmacokinetic Model for Naphthalene in Rats and Mice To Probe Species Differences

Biotechnology Progress ◽

10.1021/bp990057t ◽

1999 ◽

Vol 15 (3) ◽

pp. 540-555 ◽

Cited By ~ 35

Author(s):

D.J. Quick ◽

M.L. Shuler

Keyword(s):

Pharmacokinetic Model ◽

Species Differences ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Rats And Mice ◽

Vitro Data ◽

In Vitro Data

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Physiologically based pharmacokinetic model development for trazodone: application to paediatric dose projection

10.26226/morressier.5971be87d462b80290b534f2 ◽

2017 ◽

Author(s):

F. Calisti

Keyword(s):

Pharmacokinetic Model ◽

Model Development ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Paediatric Dose

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Risk Assessment of Perfluorooctane Sulfonate (PFOS) using Dynamic Age Dependent Physiologically based Pharmacokinetic Model (PBPK) across human lifetime

Environmental Research ◽

10.1016/j.envres.2021.111287 ◽

2021 ◽

pp. 111287

Author(s):

Deepika Deepika ◽

Raju Prasad Sharma ◽

Marta Schuhmacher ◽

Vikas Kumar

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Perfluorooctane Sulfonate ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Age Dependent

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Human risk assessment of di-isobutyl phthalate through the application of a developed physiologically based pharmacokinetic model of di-isobutyl phthalate and its major metabolite mono-isobutyl phthalate

Archives of Toxicology ◽

10.1007/s00204-021-03057-5 ◽

2021 ◽

Author(s):

Seung-Hyun Jeong ◽

Ji-Hun Jang ◽

Hea-Young Cho ◽

Yong-Bok Lee

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Major Metabolite ◽

Physiologically Based Pharmacokinetic Model ◽

Human Risk Assessment ◽

Human Risk ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically‐Based Pharmacokinetic Model for Alectinib, Ruxolitinib, and Panobinostat in The Presence of Cancer, Renal Impairment, and Hepatic Impairment

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2282 ◽

2021 ◽

Author(s):

Mo'tasem M. Alsmadi

Keyword(s):

Renal Impairment ◽

Hepatic Impairment ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Development of a Physiologically-Based Pharmacokinetic Model for Perchloroethylene Using Tissue Concentration-Time Data

Toxicology and Applied Pharmacology ◽

10.1006/taap.1994.1179 ◽

1994 ◽

Vol 128 (1) ◽

pp. 50-59 ◽

Cited By ~ 15

Author(s):

C.E. Dallas ◽

X.M. Chen ◽

K. Obarr ◽

S. Muralidhara ◽

P. Varkonyi ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Tissue Concentration ◽

Physiologically Based Pharmacokinetic Model ◽

Time Data ◽

Physiologically Based Pharmacokinetic ◽

Concentration Time ◽

Physiologically Based

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