scholarly journals Early life stress modulates oxytocin effects on limbic system during acute psychosocial stress

2014 ◽  
Vol 9 (11) ◽  
pp. 1828-1835 ◽  
Author(s):  
Simone Grimm ◽  
Karin Pestke ◽  
Melanie Feeser ◽  
Sabine Aust ◽  
Anne Weigand ◽  
...  
Keyword(s):  
Limbic System ◽  
Life Stress ◽  
Early Life ◽  
Psychosocial Stress ◽  
Early Life Stress ◽  
Acute Psychosocial Stress

scholarly journals Amygdala–Hippocampal Connectivity Changes During Acute Psychosocial Stress: Joint Effect of Early Life Stress and Oxytocin

2015 ◽  
Vol 40 (12) ◽  
pp. 2736-2744 ◽  
Author(s):  
Yan Fan ◽  
Karin Pestke ◽  
Melanie Feeser ◽  
Sabine Aust ◽  
Jens C Pruessner ◽  
...  
Keyword(s):  
Life Stress ◽  
Early Life ◽  
Psychosocial Stress ◽  
Early Life Stress ◽  
Joint Effect ◽  
Acute Psychosocial Stress

scholarly journals Early Life Stress Enhances the Vulnerability to Chronic Psychosocial Stress and Experimental Colitis in Adult Mice

Endocrinology ◽  
2008 ◽  
Vol 149 (6) ◽  
pp. 2727-2736 ◽  
Author(s):  
Alexa H. Veenema ◽  
Stefan O. Reber ◽  
Sandra Selch ◽  
Florian Obermeier ◽  
Inga D. Neumann
Keyword(s):  
Life Stress ◽  
Early Life ◽  
Psychosocial Stress ◽  
Early Life Stress ◽  
Experimental Colitis ◽  
Adult Mice ◽  
Chronic Psychosocial Stress

Early life stress predicts cortisol response to psychosocial stress in healthy young adults

PsyCh Journal ◽  
2019 ◽  
Vol 8 (3) ◽  
pp. 353-362 ◽  
Author(s):  
Huihui Zhang ◽  
Zhuxi Yao ◽  
Li Lin ◽  
Xiaofang Sun ◽  
Xia Shi ◽  
...  
Keyword(s):  
Young Adults ◽  
Life Stress ◽  
Early Life ◽  
Psychosocial Stress ◽  
Early Life Stress ◽  
Cortisol Response

scholarly journals The 5-HTTLPR genotype, early life adversity and cortisol responsivity to psychosocial stress in women

BJPsych Open ◽  
2018 ◽  
Vol 4 (4) ◽  
pp. 180-185 ◽  
Author(s):  
Jurate Aleknaviciute ◽  
Joke H. M. Tulen ◽  
Yolanda B. de Rijke ◽  
Mark van der Kroeg ◽  
Cornelis G. Kooiman ◽  
...  
Keyword(s):  
Childhood Maltreatment ◽  
Life Stress ◽  
Early Life ◽  
Psychosocial Stress ◽  
Social Stress ◽  
Stress Test ◽  
Early Life Stress ◽  
Trier Social Stress Test ◽  
Early Life Adversity ◽  
Personality Psychopathology

BackgroundThe serotonin transporter gene-linked polymorphic region (5-HTTLPR) has previously been associated with hypothalamus–pituitary–adrenal axis function. Moreover, it has been suggested that this association is moderated by an interaction with stressful life experiences.AimsTo investigate the moderation of cortisol response to psychosocial stress by 5-HTTLPR genotype, either directly or through an interaction with early life stress.MethodA total of 151 women, 85 of which had personality psychopathology, performed the Trier Social Stress Test while cortisol responsivity was assessed.ResultsThe results demonstrate a main effect of genotype on cortisol responsivity. Women carrying two copies of the long version of 5-HTTLPR exhibited stronger cortisol responses to psychosocial stress than women with at least one copy of the short allele (P = 0.03). However, the proportion of the variance of stress-induced cortisol responsivity explained by 5-HTTLPR genotype was not further strengthened by including early life adversity as a moderating factor (P = 0.52).ConclusionsOur results highlight the need to clarify gender-specific biological factors influencing the serotonergic system. Furthermore, our results suggest that childhood maltreatment, specifically during the first 15 years of life, is unlikely to exert a moderating influence of large effect on the relationship between the 5-HTTLPR genotype and cortisol responsivity to psychosocial stress.Declaration of interestNone.

The effects of early life stress on context fear generalization in adult rats.

2019 ◽  
Vol 133 (1) ◽  
pp. 50-58 ◽  
Author(s):  
Nathalie D. Elliott ◽  
Rick Richardson
Keyword(s):  
Life Stress ◽  
Early Life ◽  
Early Life Stress ◽  
Adult Rats ◽  
Fear Generalization
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