scholarly journals Alexithymia and Somatization in Agenesis of the Corpus Callosum

2021 ◽  
Author(s):  
Lynn K Paul ◽  
Shawneen R Pazienza ◽  
Warren S Brown
Keyword(s):  
Corpus Callosum ◽  
Emotional Experience ◽  
Emotion Processing ◽  
Critical Role ◽  
Physical Symptoms ◽  
Interhemispheric Transfer ◽  
Cerebral Hemispheres ◽  
Emotional Coping ◽  
Cognitive Dimensions

Abstract Deficient communication between the cerebral hemispheres is one of several prevailing neurobiological explanations for alexithymia and has been strongly supported by research on patients with commissurotomy. We examined self-reported symptoms of alexithymia in adults with agenesis of the corpus callosum (AgCC), a condition characterized by more subtle reductions in interhemispheric transfer than in commissurotomy. 16 adults with AgCC and FSIQ > 80 were compared with 15 age- and IQ-matched neurotypical controls. The AgCC group endorsed greater difficulty identifying and describing feelings and more vague physical symptoms than controls, but similar levels of emotional experience and emotional coping. This finding of impaired emotional interpretation with intact emotional experience is consistent with findings in callosotomy patients, implicating the critical role of the corpus callosum in cognitive dimensions of emotion processing. Further study of alexithymia in AgCC using task-based measures may help clarify the nature of this relationship.

Applications of Advances in Neuroscience to Assessment of Brain Injury

2008 ◽  
Vol 9 (1) ◽  
pp. 36-43
Author(s):  
Gina Geffen
Keyword(s):  
Brain Injury ◽  
Corpus Callosum ◽  
Brain Imaging ◽  
Imaging Techniques ◽  
Interhemispheric Transfer ◽  
Tactile Information ◽  
Normal Individuals

AbstractThe application of neuroscience advances to brain injury is addressed in the context of our studies of the role of the corpus callosum in the interhemispheric transfer of auditory and tactile information. The outcome of these studies, which were conducted over a period of 30 years in normal individuals as well as those with congenital and acquired lesions of the corpus callosum, have since been confirmed and extended by modern brain imaging techniques. These techniques nevertheless continue to rely on the use of sensitive, specific, valid and reliable behavioural testing paradigms.

Heart-Brain Neurodynamics

2019 ◽  
pp. 191-219 ◽  
Author(s):  
Rollin McCraty
Keyword(s):  
Emotional Experience ◽  
Critical Role ◽  
The Body ◽  
Emotional Life ◽  
Physiological Basis ◽  
Brain Functions ◽  
Emotional System ◽  
The Relationship ◽  
The Brain

As pervasive and vital as they are in human experience, emotions have long remained an enigma to science. This chapter explores recent scientific advances that clarify central controversies in the study of emotion, including the relationship between intellect and emotion and the historical debate on the source of emotional experience. Particular attention is given to the intriguing body of research illuminating the critical role of ascending input from the body to the brain in the generation and perception of emotions. This discussion culminates in the presentation of a new, systems-oriented model of emotion in which the brain functions as a complex pattern-matching system, continually processing input from both the external and internal environments. From this perspective, it is shown that the heart is a key component of the emotional system, thus providing a physiological basis for the long-acknowledged link between the heart and our emotional life.

The Role of the SLP in Autism Spectrum Disorder Screening and Assessment

2008 ◽  
Vol 15 (2) ◽  
pp. 50-59 ◽  
Author(s):  
Amy Philofsky
Keyword(s):  
Language Development ◽  
Critical Role ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Children With Asd ◽  
Prevalence Estimates ◽  
Notable Increase ◽  
Screening Assessment ◽  
Critical Components

AbstractRecent prevalence estimates for autism have been alarming as a function of the notable increase. Speech-language pathologists play a critical role in screening, assessment and intervention for children with autism. This article reviews signs that may be indicative of autism at different stages of language development, and discusses the importance of several psychometric properties—sensitivity and specificity—in utilizing screening measures for children with autism. Critical components of assessment for children with autism are reviewed. This article concludes with examples of intervention targets for children with ASD at various levels of language development.

A critical role of iNOS-derived Nitric Oxide (NO) and progesterone in implantation

1998 ◽  
Vol 5 (1) ◽  
pp. 115A-115A
Author(s):  
K CHWALISZ ◽  
E WINTERHAGER ◽  
T THIENEL ◽  
R GARFIELD
Keyword(s):  
Nitric Oxide ◽  
Critical Role

Interhemispheric transfer evaluation in multiple sclerosis 1The authors would like to thank Claude-Alain Hauert and Christoph Michel for their assistance in the evaluation of motor tapping and Michel Habib for his suggestions and comments. This work was supported by a grant from the Swiss Society of Multiple Sclerosis.

2000 ◽  
Vol 59 (3) ◽  
pp. 150-158 ◽  
Author(s):  
Nadia Ortiz ◽  
Michael Reicherts ◽  
Alan J. Pegna ◽  
Encarni Garran ◽  
Michel Chofflon ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Corpus Callosum ◽  
Lexical Decision ◽  
Dichotic Listening ◽  
Neurological Impairment ◽  
Interhemispheric Transfer ◽  
Decision Task ◽  
Swiss Society ◽  
Listening Test ◽  
Relapsing Remitting

Patients suffering from Multiple Sclerosis (MS) have frequently been found to suffer from damage to callosal fibers. Investigations have shown that this damage is associated with signs of hemisphere disconnections. The aim of our study was to provide evidence for the first signs of interhemispheric dysfunction in a mildly disabled MS population. Therefore, we explored whether the Interhemispheric Transfer (IT) deficit is multi-modal and sought to differentiate two MS evolution forms, on the basis of an interhemispheric disconnection index. Twenty-two patients with relapsing-remitting form of MS (RRMS) and 14 chronic-progressive (CPMS) were compared with matched controls on four tasks: a tachistoscopic verbal and non-verbal decision task, a dichotic listening test, cross tactile finger localization and motor tapping. No overall impairment was seen. The dichotic listening and lexical decision tasks were the most sensitive to MS. In addition, CPMS patients' IT was more impaired and was related to the severity of neurological impairment. The different sizes of the callosal fibers, which determine their vulnerability, may explain the heterogeneity of transfer through the Corpus Callosum. Therefore, evaluation of IT may be of value as an index of evolution in MS.

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