scholarly journals Effects of Conjugated Linoleic Acid. 1. Fatty Acid Modification of Yolks and Neonatal Fatty Acid Metabolism

2000 ◽  
Vol 79 (6) ◽  
pp. 817-821 ◽  
Author(s):  
M.A. Latour ◽  
A.A. Devitt ◽  
R.A. Meunier ◽  
J.J. Stewart ◽  
B.A. Watkins
2007 ◽  
Vol 2007 ◽  
pp. 151-151 ◽  
Author(s):  
E. J. Kim ◽  
J. D. Wood ◽  
I. Richardson ◽  
S. A. Huws ◽  
N. D. Scollan

Previous studies have shown that including fish oil (FO) in the diet of beef cattle resulted in increased long chain C20n-3 PUFA (C20:5n-3 and C22:6n-3) in muscle resulting in a lower n-6:n-3 ratio (Scollan et al., 2005). Fish oil is considered to be a good inhibitor of biohydrogenation in the rumen, resulting in increased production of C18:1 trans-11 (Vaccenic acid), the precursor for conjugated linoleic acid (CLA cis-9, trans-11) in muscle. This study investigated the effects of incremental levels of FO in the diet on fatty acid metabolism in the rumen.


1990 ◽  
Vol 64 (4) ◽  
pp. 303-309 ◽  
Author(s):  
Takeya Minematsu ◽  
Seietsu Yamazaki ◽  
Yoshinori Uji ◽  
Hiroaki Okabe ◽  
Masataka Korenaga ◽  
...  

ABSTRACTThe effect of linolenic acid (C18:3ω3) on the development of Strongyloides ratti first-stage larvae (L1) in culture was studied. The fatty acid composition of S. ratti free-living generations was analyzed by gas chromatography. L1 had abundant linoleic acid (C18:2ω6) but its proportion decreased with development. On the contrary, eicosapentaenoic acid (C20:5ω3) and C20:4ω3 were prominent in the filariform larva (L3). Because C20:5ω3 is generally synthesized from C18:3ω3 via C20:4ω3, the high ratio of C20:5ω3/C18:3ω3 of L3 in all the free-living generations suggested that polyunsaturated fatty acid metabolism, particularly the ω-3 series, and eicosanoids produced had important roles in the development of S. ratti L1.


2011 ◽  
Vol 59 (3) ◽  
pp. 1020-1030 ◽  
Author(s):  
Shyamalie D. Senadheera ◽  
Giovanni M. Turchini ◽  
Thanongsak Thanuthong ◽  
David S. Francis

Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1686 ◽  
Author(s):  
Yuan Kei Ching ◽  
Yit Siew Chin ◽  
Mahenderan Appukutty ◽  
Vasudevan Ramanchadran ◽  
Choo Yee Yu ◽  
...  

Fatty acid desaturase 1 (FADS1) gene controls the fatty acid metabolism pathway in the human body. The lower intake of α-linolenic acid (ALA) than linoleic acid (LA) among vegetarians may disrupt the fatty acid metabolism and limit the conversion of ALA to anti-inflammatory products such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). This cross-sectional study aimed to determine the interaction of rs174547 in FADS1 gene with LA and ALA on metabolic syndrome (MetS) components. A total of 200 Chinese and Indian vegetarians in Kuala Lumpur and Selangor, Malaysia participated in the present study. The data on socio-demographic characteristics, vegetarianism practices, dietary practices, anthropometric measurements, blood pressure (BP), and overnight venous fasting blood samples were collected from the vegetarians. The rs174547 in FADS1 gene was significantly associated with MetS and its components such as waist circumference (WC) and fasting blood glucose (FBG). Multiple logistic regression analyses revealed that vegetarians with TT genotype of rs174547 in FADS1 gene had higher odds for MetS, larger WC, higher BP, and a lower level of HDL-c. Two-way ANOVA analysis showed that LA interacts with rs174547 in FADS1 gene to affect HDL-c (p < 0.05) among vegetarians. The present findings suggest the need to develop dietary guidelines for vegetarians in Malaysia. Prospective studies are also needed to affirm the interaction between LA and rs174547 in FADS1 gene on HDL-c among Malaysian vegetarians.


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