scholarly journals Broiler breeder survivors of chronic unilateral pulmonary artery occlusion produce progeny resistant to pulmonary hypertension syndrome (ascites) induced by cool temperatures

1999 ◽  
Vol 78 (3) ◽  
pp. 404-411 ◽  
Author(s):  
RF Wideman ◽  
H French
Keyword(s):  
Pulmonary Hypertension ◽  
Pulmonary Artery ◽  
Artery Occlusion ◽  
Pulmonary Hypertension Syndrome ◽  
Broiler Breeder ◽  
Unilateral Pulmonary Artery Occlusion

UNILATERAL PULMONARY ARTERY OCCLUSION IN MAN

1957 ◽  
Vol 34 (2) ◽  
pp. 206-227 ◽  
Author(s):  
Bernard L. Brofman ◽  
Bernard L. Charms ◽  
Paul M. Kohn ◽  
John Elder ◽  
Robert Newman ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Artery Occlusion ◽  
Unilateral Pulmonary Artery Occlusion

Microvascular injury distal to unilateral pulmonary artery occlusion

1981 ◽  
Vol 51 (4) ◽  
pp. 845-851 ◽  
Author(s):  
R. L. Johnson ◽  
S. S. Cassidy ◽  
M. Haynes ◽  
R. L. Reynolds ◽  
W. Schulz
Keyword(s):  
Pulmonary Artery ◽  
Left Lung ◽  
Left Pulmonary Artery ◽  
Artery Occlusion ◽  
Diffusing Capacity ◽  
Pulmonary Capillary Blood Flow ◽  
Pulmonary Capillary ◽  
Pulmonary Capillary Blood ◽  
Rebreathing Method ◽  
Unilateral Pulmonary Artery Occlusion

We explored three questions: 1) does edema fluid accumulate distal to temporary unilateral pulmonary artery occlusion (TUPAO); 2) if so how rapidly does it accumulate; and 3) how is it affected by positive end-expiratory pressure (PEEP)? Using a tracheal divider we measured pulmonary capillary blood flow (Qc), tissue volume (Vt), and diffusing capacity (DLCO) in each lung with a rebreathing method. After control measurements in 12 dogs, the left pulmonary artery was occluded and measurements were repeated at intervals during 4 h of occlusion and 30 min after release of the occlusion. Six of the dogs were ventilated with 10 cmH2O PEEP. Finally the lungs were removed, weighed, and fixed for histology. TUPAO caused a 29% increase in Vt of the left lung without PEEP and a 59% increase with PEEP. After release of the occlusion, Qc and DLCO in the left lung returned to control levels within 30 min in dogs not on PEEP but remained depressed in dogs ventilated with PEEP even though PEEP was removed. At postmortem the left lung weighed more than expected in both groups of dogs but was significantly heavier in those on PEEP. Histology confirmed bronchovascular cuffing with edema and hemorrhage.

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