scholarly journals Acute Liver Failure Due to Echovirus 9 Associated With Persistent B-Cell Depletion From Rituximab

2017 ◽  
Vol 4 (3) ◽  
Author(s):  
Kristina L Bajema ◽  
Paul D Simonson ◽  
Alex L Greninger ◽  
Basak Çoruh ◽  
Paul S Pottinger ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Next Generation Sequencing ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
B Cell ◽  
Early Recognition ◽  
Etiologic Agent ◽  
Cell Depletion ◽  
B Cell Depletion ◽  
Generation Sequencing

Abstract We describe a case of fatal acute liver failure due to echovirus 9 in the setting of persistent B-cell depletion and hypogammaglobulinemia 3 years after rituximab therapy. Metagenomic next-generation sequencing further specified the etiologic agent. Early recognition may provide an opportunity for interventions including intravenous immunoglobulin and liver transplantation.

Next‐generation sequencing of the intrahepatic antibody repertoire delineates a unique B‐cell response in HBV‐associated acute liver failure

2020 ◽  
Vol 27 (8) ◽  
pp. 847-851
Author(s):  
Zhaochun Chen ◽  
Chen‐Hsiang Shen ◽  
Ronald E. Engle ◽  
Fausto Zamboni ◽  
Peter D. Kwong ◽  
...  
Keyword(s):  
Next Generation Sequencing ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
B Cell ◽  
Cell Response ◽  
Antibody Repertoire ◽  
Next Generation ◽  
Generation Sequencing ◽  
B Cell Response

High affinity anti-BSEP antibodies after liver transplantation for PFIC-2 - Successful treatment with immunoadsorption and B-cell depletion

2016 ◽  
Vol 20 (7) ◽  
pp. 987-993 ◽  
Author(s):  
Ralf Kubitz ◽  
Carola Dröge ◽  
Stefanie Kluge ◽  
Jan Stindt ◽  
Claudia Stross ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
B Cell ◽  
Successful Treatment ◽  
Cell Depletion ◽  
B Cell Depletion ◽  
High Affinity

scholarly journals Viral Surveillance in Serum Samples From Patients With Acute Liver Failure By Metagenomic Next-Generation Sequencing

2017 ◽  
Vol 65 (9) ◽  
pp. 1477-1485 ◽  
Author(s):  
Sneha Somasekar ◽  
Deanna Lee ◽  
Jody Rule ◽  
Samia N Naccache ◽  
Mars Stone ◽  
...  
Keyword(s):  
Next Generation Sequencing ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Next Generation ◽  
Serum Samples ◽  
Viral Surveillance ◽  
Generation Sequencing

Chemotherapy-induced B-cell depletion in hepatoblastoma patients undergoing ABO-incompatible living donor liver transplantation

2016 ◽  
Vol 20 (3) ◽  
pp. 401-407 ◽  
Author(s):  
Hiroyuki Kanazawa ◽  
Akinari Fukuda ◽  
Vidyadhar Padmakar Mali ◽  
Tri Hening Rahayatri ◽  
Yoshihiro Hirata ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
B Cell ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Cell Depletion ◽  
B Cell Depletion ◽  
Donor Liver ◽  
Donor Liver Transplantation

Comprehensive detection of viruses in pediatric patients with acute liver failure using next-generation sequencing

2017 ◽  
Vol 96 ◽  
pp. 67-72 ◽  
Author(s):  
Takako Suzuki ◽  
Jun-ichi Kawada ◽  
Yusuke Okuno ◽  
Satoshi Hayano ◽  
Kazuhiro Horiba ◽  
...  
Keyword(s):  
Next Generation Sequencing ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Pediatric Patients ◽  
Next Generation ◽  
Generation Sequencing
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