scholarly journals Cardiac Electrophysiology Laboratories: A Potential Target for Antimicrobial Stewardship?

2015 ◽  
Vol 2 (suppl_1) ◽  
Author(s):  
Westyn Branch-Elliman ◽  
Maggie Stanislawski ◽  
Judith Strymish ◽  
Howard S. Gold ◽  
Kalpana Gupta ◽  
...  
Keyword(s):  
Antimicrobial Stewardship ◽  
Cardiac Electrophysiology ◽  
Potential Target

Cardiac Electrophysiology Laboratories: A Potential Target for Antimicrobial Stewardship and Quality Improvement?

2016 ◽  
Vol 37 (9) ◽  
pp. 1005-1011 ◽  
Author(s):  
Westyn Branch-Elliman ◽  
Maggie Stanislawski ◽  
Judith Strymish ◽  
Anna E. Barón ◽  
Kalpana Gupta ◽  
...  
Keyword(s):  
Quality Improvement ◽  
Antimicrobial Stewardship ◽  
Antimicrobial Therapy ◽  
Cardiac Electrophysiology ◽  
Electronic Device ◽  
Antimicrobial Use ◽  
Cardiac Device ◽  
Potential Target ◽  
Procedural Volume ◽  
Improvement Programs

BACKGROUNDInfections following cardiovascular implantable electronic device (CIED) procedures, including pacemaker and implantable cardioverter–defibrillators, are devastating and costly. Preimplantation prophylactic antimicrobials are effective for reducing postprocedural infections. However, routine postprocedural antimicrobials are not associated with improved outcomes, and they may be harmful. Thus, we sought to characterize antimicrobial use patterns following CIED procedures.DESIGNAll patients who underwent CIED procedures from October 1, 2007 to September 30, 2013 and had procedural information entered into the VA Clinical Assessment Reporting and Tracking (CART) software program were included in this study. All antibiotic prescriptions lasting more than 24 hours following device implantation or revision were identified using pharmacy databases, and postprocedural antibiotic use lasting more than 24 hours was characterized.RESULTSIn total, 3,712 CIED procedures were performed at 34 VA facilities on 3,570 patients with a mean age of 71.7 years (standard deviation [SD], 11.1 years), 98.4% of whom were male. Postprocedural antibiotics >24 hours were prescribed following 1,579 of 3,712 CIED procedures (42.5%). The median duration of therapy was 5 days (interquartile range [IQR], 3–7 days). The most commonly prescribed antibiotic was cephalexin (1,152 of 1,579; 72.9%), followed by doxycycline (118 of 1,579; 7.47%) and ciprofloxacin (93 of 1,579; 5.9%). Vancomycin was used in 73 of 1,579 prescriptions (4.62%). Among the highest quartile of procedural volume, prescribing practices varied considerably, ranging from 3.2% to 77.6%.CONCLUSIONSNearly 1 in 2 patients received prolonged postprocedural antimicrobial therapy following CIED procedures, and the rate of postprocedural antimicrobial therapy use varied considerably by facility. Given the lack of demonstrated benefit of routine prolonged antimicrobial therapy following CIED procedures, antimicrobial use following cardiac device interventions may be a potential target for quality improvement programs and antimicrobial stewardship.Infect Control Hosp Epidemiol 2016;37:1005–1011

scholarly journals Implementation of Infection Prevention and Antimicrobial Stewardship in Cardiac Electrophysiology Laboratories: Results from the SHEA Research Network

2017 ◽  
Vol 38 (4) ◽  
pp. 496-498 ◽  
Author(s):  
Preeti Mehrotra ◽  
Kalpana Gupta ◽  
Judith Strymish ◽  
Daniel B. Kramer ◽  
Anne Lambert-Kerzner ◽  
...  
Keyword(s):  
Antimicrobial Stewardship ◽  
Cardiac Electrophysiology ◽  
Infection Prevention ◽  
Research Network ◽  
Antimicrobial Use ◽  
Cross Sectional Survey ◽  
Cross Sectional

Infection prevention in electrophysiology (EP) laboratories is poorly characterized; thus, we conducted a cross-sectional survey using the SHEA Research Network. We found limited uptake of basic interventions, such as surveillance and appropriate peri-procedural antimicrobial use. Further study is needed to identify ways to improve infection prevention in this setting.

Imaging of central cannabinoid CB1 receptors, a potential target for therapeutic agents in movement disorders

2005 ◽  
Vol 32 (06) ◽  
Author(s):  
G Berding ◽  
U Schneider ◽  
P Gielow ◽  
R Buchert ◽  
WH Knapp ◽  
...  
Keyword(s):  
Movement Disorders ◽  
Therapeutic Agents ◽  
Cb1 Receptors ◽  
Potential Target

Implementation status of antimicrobial stewardship programs in hospitals: A quantitative analysis study in Ho Chi Minh city, Vietnam

MedPharmRes ◽  
2020 ◽  
Vol 4 (2) ◽  
pp. 34-39
Author(s):  
Thi-Hai-Yen Nguyen ◽  
Truong Van Dat ◽  
Phuong-Thao Huynh ◽  
Chi-Thuong Tang ◽  
Vinh-Chau Van Nguyen ◽  
...  
Keyword(s):  
Antimicrobial Stewardship ◽  
Health Workers ◽  
Cross Sectional Study ◽  
Ho Chi Minh City ◽  
Multi Drug Resistance ◽  
Cross Sectional ◽  
Clostridioides Difficile ◽  
The Status ◽  
Specific Assessment ◽  
Implementation Status

Vietnam has one of the highest multi drug resistance in Asia. Although, despite many efforts to implement the Antimicrobial Stewardship Programs (the ASP) since 2016, studies that on the implementation policy are very lacking of this program are limited. For that reason, we conducted this cross-sectional study to analyze the viewpoint of health workers (HWs) on the implementation of the ASP at some hospitals in Ho Chi Minh City (HCMC). An assessment of 234 HWs showed that the implementation of the ASP in HCMC hospitals was above average (62.7/100.0). A barrier to the implementation consisted of the deficiency in finances, guidelines for diagnosis, and specific interventions for some common infections, such as distributing current antibiogram and monitoring rate of Clostridioides difficile infections. These were the widely recognized problems in initially implementing the ASP. Although most HWs are aware of the importance of implementing the ASP (79.1%), the specific assessment has not been recorded clearly due to the numerous neutral responses. Despite the support of the leadership, the implementation still faces many difficulties and limitations, especially in 3rd and 4th class hospitals. Besides, there was a lack of wide dissemination of information on the ASP at each unit. To generalize the status of the ASP implementation, researchers should conduct qualitative and quantitative studies with a larger scale.

High-Frequency Cardiac Electrophysiology

2019 ◽  
Author(s):  
Pavel Jurak ◽  
Josef Halamek ◽  
Pavel Leinveber ◽  
Filip Plesinger ◽  
Ivo Viscor ◽  
...  
Keyword(s):  
High Frequency ◽  
Cardiac Electrophysiology
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