scholarly journals High HIV Incidence Among Men Who Have Sex With Men in 8 Chinese Cities: Results From a Trial

2020 ◽  
Vol 7 (5) ◽  
Author(s):  
Wenting Huang ◽  
Yehua Wang ◽  
Haidong Lu ◽  
Dan Wu ◽  
Stephen W Pan ◽  
...  
Keyword(s):  
Hiv Testing ◽  
Incidence Rate ◽  
Sexual Behaviors ◽  
Subgroup Analysis ◽  
Cox Regression ◽  
Large Trial ◽  
Hiv Incidence ◽  
Hiv Seroconversion ◽  
Sex With Men

Abstract Background In China, while the overall HIV prevalence has been decreasing within key populations, the epidemic among men who have sex with men (MSM) is still on the rise. This study aims to assess the HIV incidence rate and identify driving forces of HIV seroconversion among MSM in a closed cohort. Methods This study is a secondary analysis of a large trial of HIV testing promotion among Chinese MSM in 2016–2017. Sexual behaviors, HIV testing activities, and HIV serostatus were measured at baseline and follow-up every 3 months. HIV seroconversion in this study was defined as a self-reported HIV-positive test result. Participants who reported testing for HIV at least twice during different follow-up periods were included. Subgroup analysis and Cox regression were used to examine the correlates with HIV seroconversion. Results Overall, 347 participants were included in this study, with a mean age of 25.3 ± 6.1, and 71.2% were migrants. The sociodemographic characteristics of the included participants were similar to the rest of the participants in the trial (n = 1034); 7.2% (25/347) of participants seroconverted during the study period, resulting in an incidence rate of 15.56/100 person-years. In subgroup analysis, the HIV incidence rate was higher among migrants than nonmigrants (incidence rate ratio, 1.26; 95% confidence interval [CI], 0.47–3.87). In the time-dependent Cox regression model, bisexual MSM had a higher risk of contracting HIV than gay men (adjusted hazard ratio, 2.19; 95% CI, 1.02–4.72). Conclusions Our findings suggest a high HIV incidence rate among Chinese MSM. Further expansion of pre-exposure prophylaxis and other effective HIV prevention interventions are urgently needed.

The electronic identification protects privacy and has consistent HIV incidence with the traditional real-name follow-up among Chinese MSM: A 24-month prospective cohort study (Preprint)

2021 ◽  
Author(s):  
Jie Wei ◽  
Xiangjun Zhang ◽  
Jing Zhang ◽  
Zhenxing Chu ◽  
Wenqing Geng ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Cox Regression ◽  
Retention Rates ◽  
Kappa Statistics ◽  
Hiv Incidence ◽  
Predictive Values ◽  
The Real ◽  
Hiv Seroconversion ◽  
Sex With Men

BACKGROUND Men who have sex with men (MSM) usually face stigma and discrimination in relation to their sexual orientation and have the fear of identification disclosure, which may prevent them from taking HIV tests and participating in research studies. The traditionally used real-name identification methods might lead to biased estimates in HIV incidence. OBJECTIVE This study evaluated an electronic identification (eID) method in estimating HIV incidence among MSM using a social media application that allowed good protection of privacy than the real-name identification. METHODS From January 2018 to January 2020, a WeChat OpenID identifier was used to generate and assign eID for MSM who attended the First Affiliated Hospital of China Medical University for voluntary counselling and testing (VCT) services. The inclusion criteria were men aged 18 years and older who had consensual anal or oral sex with men in the previous 12 months and agreed to WeChat authorization. The eID group was compared with the real-name identification group (PID) that we acquired through HIV testing information regarding participants’ demographic and behavioral characteristics and HIV incidence. Sensitivity, specificity, positive and negative predictive values, and Kappa statistics were used to compare the consistency of the two groups. Cox regression was used to assess factors that were associated with HIV infection during the follow-up period. RESULTS Of 1499 WeChat OpenID users, 1133 participants were identified and linked to their traditional PID and some participants used multiple OpenIDs. The Kappa consistency between eID and traditional PID method were 0.753. At baseline, 4.2% participants in eID group received an HIV positive testing result, which was comparable to PID group (5.4%, Kappa=0.992). Thirty-five participants infected HIV during the follow-up period. The incidence of HIV infection was 7.3/100 person-years for eID group (95% CI, 5.4-10.1) and 5.8/100 person-years for PID group (95% CI, 4.2-8.0), and the consistency was high (Kappa=0.712, P>.05). The retention rates between eID and PID group were also accordant (Kappa=0.722). Number of sexual partners, recent unprotected anal sex, and recent party drug use were associated with HIV seroconversion. CONCLUSIONS The eID method that allowed anonymous tests and multiple visits had consistent results compared to the traditional real-name PID method. This method can be scaled up in future prevention and testing programs in HIV high risk populations with high privacy and confidentiality demands.

scholarly journals HIV incidence among men who have sex with men using geosocial networking smartphone application in Beijing, China: an open cohort study

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Guo-Dong Mi ◽  
Bin-Bin Zhang ◽  
Fei Yu ◽  
Xian-Long Ren ◽  
Jason J. Ong ◽  
...  
Keyword(s):  
Hiv Risk ◽  
Sexual Behaviors ◽  
Smartphone Application ◽  
Consistent Condom ◽  
Hiv Incidence ◽  
Anal Sex ◽  
Hiv Test ◽  
Hiv Seroconversion ◽  
Geosocial Networking ◽  
Sex With Men

Abstract Background Sexual transmission among men who have sex with men (MSM) is the dominant route of HIV transmission in China. Extensive use of geosocial networking (GSN) smartphone application (app) has dramatically changed the pattern of sexual behaviors and HIV risk among MSM, but data on HIV incidence and the changing risk behaviors of GSN app-using MSM are limited. We aims to assess the HIV incidence and its correlates among gay GSN app-using MSM in China. Methods We constructed an open cohort which was initiated and maintained using a GSN app to assess the HIV incidence among app-using MSM, recruited from June 2017 to December 2018. MSM completed an online questionnaire on their sociodemographic characteristics, sexual behaviors, recreational drug use and sexually transmitted infections status. Then each man had an HIV test, and those tested negatives were enrolled into the cohort. Participants completed follow-ups with additional HIV tests though the app during the study period, and were censored at HIV seroconversion or study end date. HIV incidence was calculated by dividing the sum of observed HIV seroconversions by the observed person-time. Univariate (Chi-square test and Fisher’s exact test) and multivariate (proportional hazards regression) analyses were used to examine correlates of HIV incidence. Results A total of 6957 HIV negative MSM were enrolled in the open cohort, 37 seroconversions occurred among 1937 men contributing 1065 observed person-years: HIV incidence was 3.47 per 100 person-years [95% confidence interval (CI): 2.37–4.57]. More than five sexual partners [hazard ratio (HR) = 2.65, 95% CI: 1.04–6.67], and sex with HIV positive partners (HR = 3.82, 95% CI: 1.16–12.64) in the preceding six months were positively associated with HIV seroconversion. Consistent condom use for anal sex (HR = 0.27, 95% CI: 0.07–0.96), and reporting insertive anal sex only (HR = 0.23, 95% CI: 0.08–0.62) in the preceding six months were protective factors for HIV seroconversion. Conclusions Tailored interventions targeting app-using MSM are urgently needed given their high risk of HIV. As a new tool for accessing MSM at higher HIV risk, GSN smartphone app could play an important role in HIV research among MSM.

scholarly journals HIV Self-Testing to Promote Serostatus Disclosure Among Men Who Have Sex With Men in China: Protocol for a Stepped Wedge Randomized Controlled Trial (Preprint)

2020 ◽  
Author(s):  
Tianyi Lu ◽  
Hang Li ◽  
Xiang Mao ◽  
Erlei Peng ◽  
Yangyang Gao ◽  
...  
Keyword(s):  
Hiv Testing ◽  
Sexual Behaviors ◽  
Controlled Trial ◽  
Sexual Partners ◽  
Hiv Status ◽  
Serostatus Disclosure ◽  
Self Testing ◽  
Hiv Serostatus ◽  
Sex With Men

BACKGROUND Disclosure of HIV serostatus is important for the prevention of HIV infection among men who have sex with men (MSM). However, knowledge of sexual partners’ HIV status among MSM in China is low. As a complement to HIV testing services, HIV self-testing (HIVST) has considerable potential to promote serostatus disclosure. OBJECTIVE The primary objective of our trial is to evaluate the effect of HIVST on improving serostatus disclosure to sexual partners. We hypothesize that MSM in an intervention condition will have a higher awareness of the HIV status of their sexual partners compared with MSM in the control condition. The secondary aims are to evaluate (i) changes in sexual behaviors after disclosure of HIV status by sexual partners, (ii) promotion of the frequency of HIV and syphilis testing on participants and their sexual partners, and (iii) factors that restrict the disclosure of HIV infection to sexual partners. We hypothesize that MSM in the intervention condition will exhibit safer sexual decision making and a higher rate of HIV testing uptake compared with MSM in the control condition. METHODS A stepped wedge randomized controlled trial will be conducted throughout China. Study recruitment of 800 MSM will be promoted through advertisements released on WeChat public accounts. Individuals who are born biologically male, aged ≥18 years, HIV negative, and who have not undergone HIV testing in the past 3 months will be recruited. Eligible men will be randomly divided (1:1:1:1) into four groups and randomized. The group cluster will initiate the intervention so that participants will be provided with 2-4 free finger prick–based HIVST kits until trial completion. The intervention period for participants in each of the four groups will be initiated at 3-month intervals. Men in both groups will be required to complete a baseline and four follow-up surveys every 3 months. The primary intervention outcome will evaluate the effect of the distribution of HIVST kits on improvement in the disclosure of sexual partners’ HIV status. The secondary outcomes will be changes in sexual behaviors after disclosure of HIV status from sexual partners, the promotion of the frequency of HIVST on participants and their sexual partners, and the factors that restrict disclosure of HIV status to sexual partners. RESULTS Subject recruitment began in August 2018. The first round of follow-up surveys post intervention is complete, with three rounds remaining to be done. Data analysis was scheduled for April 2020 and the results will be disseminated through conferences and peer-reviewed publications. CONCLUSIONS Few studies have evaluated interventions to increase knowledge of sexual partners’ HIV status among MSM. Our trial will provide information on the link between HIVST and HIV serostatus disclosure. The findings of this trial will facilitate the implementation of HIVST services to help control the spread of HIV among MSM in China. CLINICALTRIAL Chinese Clinical Trial Registry ChiCTR1800019453; http://www.chictr.org.cn/showproj.aspx?proj=30158 INTERNATIONAL REGISTERED REPORT DERR1-10.2196/17788

scholarly journals HIV Self-Testing to Promote Serostatus Disclosure Among Men Who Have Sex With Men in China: Protocol for a Stepped Wedge Randomized Controlled Trial

10.2196/17788 ◽  
2020 ◽  
Vol 9 (7) ◽  
pp. e17788
Author(s):  
Tianyi Lu ◽  
Hang Li ◽  
Xiang Mao ◽  
Erlei Peng ◽  
Yangyang Gao ◽  
...  
Keyword(s):  
Hiv Testing ◽  
Sexual Behaviors ◽  
Controlled Trial ◽  
Sexual Partners ◽  
Hiv Status ◽  
Serostatus Disclosure ◽  
Self Testing ◽  
Hiv Serostatus ◽  
Sex With Men

Background Disclosure of HIV serostatus is important for the prevention of HIV infection among men who have sex with men (MSM). However, knowledge of sexual partners’ HIV status among MSM in China is low. As a complement to HIV testing services, HIV self-testing (HIVST) has considerable potential to promote serostatus disclosure. Objective The primary objective of our trial is to evaluate the effect of HIVST on improving serostatus disclosure to sexual partners. We hypothesize that MSM in an intervention condition will have a higher awareness of the HIV status of their sexual partners compared with MSM in the control condition. The secondary aims are to evaluate (i) changes in sexual behaviors after disclosure of HIV status by sexual partners, (ii) promotion of the frequency of HIV and syphilis testing on participants and their sexual partners, and (iii) factors that restrict the disclosure of HIV infection to sexual partners. We hypothesize that MSM in the intervention condition will exhibit safer sexual decision making and a higher rate of HIV testing uptake compared with MSM in the control condition. Methods A stepped wedge randomized controlled trial will be conducted throughout China. Study recruitment of 800 MSM will be promoted through advertisements released on WeChat public accounts. Individuals who are born biologically male, aged ≥18 years, HIV negative, and who have not undergone HIV testing in the past 3 months will be recruited. Eligible men will be randomly divided (1:1:1:1) into four groups and randomized. The group cluster will initiate the intervention so that participants will be provided with 2-4 free finger prick–based HIVST kits until trial completion. The intervention period for participants in each of the four groups will be initiated at 3-month intervals. Men in both groups will be required to complete a baseline and four follow-up surveys every 3 months. The primary intervention outcome will evaluate the effect of the distribution of HIVST kits on improvement in the disclosure of sexual partners’ HIV status. The secondary outcomes will be changes in sexual behaviors after disclosure of HIV status from sexual partners, the promotion of the frequency of HIVST on participants and their sexual partners, and the factors that restrict disclosure of HIV status to sexual partners. Results Subject recruitment began in August 2018. The first round of follow-up surveys post intervention is complete, with three rounds remaining to be done. Data analysis was scheduled for April 2020 and the results will be disseminated through conferences and peer-reviewed publications. Conclusions Few studies have evaluated interventions to increase knowledge of sexual partners’ HIV status among MSM. Our trial will provide information on the link between HIVST and HIV serostatus disclosure. The findings of this trial will facilitate the implementation of HIVST services to help control the spread of HIV among MSM in China. Trial Registration Chinese Clinical Trial Registry ChiCTR1800019453; http://www.chictr.org.cn/showproj.aspx?proj=30158 International Registered Report Identifier (IRRID) DERR1-10.2196/17788

scholarly journals HIV Incidence among Men Who Have Sex with Men Using Geosocial Networking Smartphone Application in Beijing, China: an Open Cohort Study

2020 ◽  
Author(s):  
Guodong Mi ◽  
Binbin Zhang ◽  
Fei Yu ◽  
Xianlong Ren ◽  
Jason Ong ◽  
...  
Keyword(s):  
Hiv Risk ◽  
Sexual Behaviors ◽  
Smartphone Application ◽  
Consistent Condom ◽  
Hiv Incidence ◽  
Anal Sex ◽  
Hiv Test ◽  
Hiv Seroconversion ◽  
Geosocial Networking ◽  
Sex With Men

Abstract Background Sexual transmission among men who have sex with men (MSM) is the dominant route of HIV transmission in China. Extensive use of geosocial networking (GSN) smartphone application (app) have dramatically changed the patterns of sexual behaviors and HIV risk among MSM, but data on HIV incidence and changed risk behaviors of GSN app using MSM are limited.Methods We constructed an open cohort which was constructed and maintained using a GSN app to assess the HIV incidence among app-using MSM, recruited from June 2017 to December 2018. MSM completed an online questionnaire of their sociodemographic characteristics, sexual behaviors, recreational drug use and sexually transmitted infections status. Then each man had an HIV test, and those testing negative were enrolled into the cohort. Participants completed follow-ups with additional HIV tests though the app during the study period, and were censored at HIV seroconversion or study end date. HIV incidence were calculated by dividing the sum of observed HIV seroconversions by the observed person-time. Univariate (Chi-square test and Fisher’s exact test) and multivariate (proportional hazards regression) analyses were used to examine correlates of HIV incidence.Results A total of 6957 HIV negative MSM were enrolled in the open cohort, 37 seroconversions occurred among 1937 men contributing 1065 observed person-years: HIV incidence was 3.47 per 100 person-years (95%CI 2.37–4.57). HIV seroconversion was associated with the following factors in the preceding six months: more than five sexual partners (HR = 2.65 95%CI 1.04–6.67), and sex with HIV positive partners (HR = 3.82 95%CI 1.16–12.64). Consistent condom use for anal sex (HR = 0.27 95%CI 0.07–0.96), and reporting insertive anal sex only (HR = 0.23 95%CI 0.08–0.62) were protective factors for HIV seroconversion.Conclusions Tailored interventions targeting app-using MSM are urgently needed given their high risk of HIV. As a new tool for accessing MSM at higher HIV risk, GSN smartphone app-based interventions could play an important role in HIV control among MSM using combinations of biomedical and behavioral interventions.

Trend in HIV incidence in a cohort of homosexual men in Sydney: data from the Health in Men Study

Sexual Health ◽  
2008 ◽  
Vol 5 (2) ◽  
pp. 109 ◽  
Author(s):  
Fengyi Jin ◽  
Garrett P. Prestage ◽  
Ann McDonald ◽  
Tim Ramacciotti ◽  
John C. Imrie ◽  
...  
Keyword(s):  
Cox Regression ◽  
New South ◽  
Homosexual Men ◽  
Sexually Active ◽  
Hiv Incidence ◽  
Community Based ◽  
South Wales ◽  
Hiv Seroconversion ◽  
Study Database

Objectives: To determine the incidence of HIV seroconversion in a community-based cohort of homosexual men in Sydney from 2002 to 2006. Methods: Participants were recruited between 2001 and 2004 from community-based events and venues. They were tested for HIV annually at follow-up interviews. Each year, the study database was matched against the national HIV register to identify additional HIV seroconversions among men lost to active follow up. The trend in HIV incidence over time was examined using Cox regression. Results: Among 1426 participants, 52 cases of HIV seroconversion were identified between 2002 and 2006, an incidence of 0.87 per 100 person-years (95% CI: 0.65–1.14). HIV incidence varied from 1.67 per 100 person-years in 2002 to 0.39 in 2006 (P trend = 0.282). The median age of HIV seroconversion was 36.9 years, ranging from 22 to 63 years. Conclusion: In this community-based cohort of highly sexually active homosexual men in Sydney, HIV incidence was close to 1% each year and declined non-significantly between 2002 and 2006. These data are consistent with surveillance data suggesting no increase in recent HIV incidence in homosexual men in New South Wales.

scholarly journals Use of incretin-based drugs and risk of cholangiocarcinoma: Scandinavian cohort study

Diabetologia ◽  
2021 ◽  
Author(s):  
Peter Ueda ◽  
Viktor Wintzell ◽  
Mads Melbye ◽  
Björn Eliasson ◽  
Ann-Marie Svensson ◽  
...  
Keyword(s):  
Incidence Rate ◽  
Cox Regression ◽  
Absolute Rate ◽  
Dipeptidyl Peptidase 4 ◽  
Rate Difference ◽  
Receptor Agonists ◽  
Dpp4 Inhibitors ◽  
Increased Risk ◽  
Increase In Risk

Abstract Aims/hypothesis Concerns have been raised regarding a potential association of use of the incretin-based drugs dipeptidyl peptidase 4 (DPP4) inhibitors and glucagon-like peptide-1 (GLP-1)-receptor agonists with risk of cholangiocarcinoma. We examined this association in nationwide data from three countries. Methods We used data from nationwide registers in Sweden, Denmark and Norway, 2007–2018, to conduct two cohort studies, one for DPP4 inhibitors and one for GLP-1-receptor agonists, to investigate the risk of incident cholangiocarcinoma compared with an active-comparator drug class (sulfonylureas). The cohorts included patients initiating treatment episodes with DPP4 inhibitors vs sulfonylureas, and GLP-1-receptor agonists vs sulfonylureas. We used Cox regression models, adjusted for potential confounders, to estimate hazard ratios from day 366 after treatment initiation to account for cancer latency. Results The main analyses of DPP4 inhibitors included 1,414,144 person-years of follow-up from 222,577 patients receiving DPP4 inhibitors (median [IQR] follow-up time, 4.5 [2.6–7.0] years) and 123,908 patients receiving sulfonylureas (median [IQR] follow-up time, 5.1 [2.9–7.8] years) during which 350 cholangiocarcinoma events occurred. Use of DPP4 inhibitors, compared with sulfonylureas, was not associated with a statistically significant increase in risk of cholangiocarcinoma (incidence rate 26 vs 23 per 100,000 person-years; adjusted HR, 1.15 [95% CI 0.90, 1.46]; absolute rate difference 3 [95% CI -3, 10] events per 100,000 person-years). The main analyses of GLP-1-receptor agonists included 1,036,587 person-years of follow-up from 96,813 patients receiving GLP-1-receptor agonists (median [IQR] follow-up time, 4.4 [2.4–6.9] years) and 142,578 patients receiving sulfonylureas (median [IQR] follow-up time, 5.5 [3.2–8.1] years) during which 249 cholangiocarcinoma events occurred. Use of GLP-1-receptor agonists was not associated with a statistically significant increase in risk of cholangiocarcinoma (incidence rate 26 vs 23 per 100,000 person-years; adjusted HR, 1.25 [95% CI 0.89, 1.76]; absolute rate difference 3 [95% CI -5, 13] events per 100,000 patient-years). Conclusions/interpretation In this analysis using nationwide data from three countries, use of DPP4 inhibitors and GLP-1-receptor agonists, compared with sulfonylureas, was not associated with a significantly increased risk of cholangiocarcinoma. Graphical abstract

Factors Associated With HIV Testing in Teenage Men Who Have Sex With Men

2021 ◽  
pp. 31-39
Author(s):  
Brian Mustanski ◽  
David A. Moskowitz ◽  
Kevirj O. Moran ◽  
H. Jonathon Rendina ◽  
Michael E. Newcomb ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Hiv Testing ◽  
Sexual Behaviors ◽  
Odds Ratio ◽  
Hiv Knowledge ◽  
Hiv Prevention Intervention ◽  
Hiv Test ◽  
Sexual Health Communication ◽  
Sex With Men ◽  
Regular Doctor

BACKGROUND Adolescent men who have sex with men (AMSM) have a high rate of HIV diagnoses. An estimated 14.5% of HIV infections in the United States are undiagnosed; but among 13- to 24-year-olds, the rate is 51.4%. We describe HIV testing rates and identifies salient individual, family, school, and health care influences among AMSM. METHODS Data were collected as part of SMART, an ongoing pragmatic trial of an online HIV prevention intervention for AMSM (N = 699). Measures included lifetime HIV testing, demographics, sexual behaviors, condom use, HIV education from school and family, sexual health communication with doctors, HIV knowledge, and risk attitudes. RESULTS Only 23.2% of participants had ever had an HIV test. Rates of testing increased with age (5.6% in 13- to 14-year-olds; 15.8% in 15- to 16-year-olds; 37.8% in 17- to 18-year-olds), and sexual experience was a strong predictor of testing (odds ratio: 6.54; 95% confidence interval: 3.95–11.49; P < .001). Most participants had a regular doctor (67.5%), but few had conversations about same-sex sexual behaviors (21.3%), HIV testing (19.2%), or sexual orientation (29.2%). Speaking to a doctor about HIV testing had a large effect (odds ratio: 25.29; confidence interval: 15.91–41.16; P < .001), with 75.4% who had such conversations having been tested, compared to only 10.8% of those who had not had such conversations. CONCLUSIONS Despite higher risk, few participants reported ever having received an HIV test. Data indicate pediatricians are an important, but largely untapped, source of testing and could be integral to achieving testing rates needed to end the epidemic.

scholarly journals Sexually transmitted infections and sexual behaviors of men who have sex with men in an American Deep South PrEP clinic

2020 ◽  
Vol 31 (2) ◽  
pp. 127-135 ◽  
Author(s):  
Ronnie M Gravett ◽  
Andrew O Westfall ◽  
Edgar T Overton ◽  
Kachina Kudroff ◽  
Christina A Muzny ◽  
...  
Keyword(s):  
High Risk ◽  
Sexually Transmitted Infections ◽  
Incidence Rate ◽  
Sexual Behaviors ◽  
The United States ◽  
Sexual Partners ◽  
Deep South ◽  
Multiple Sexual Partners ◽  
Sexually Transmitted ◽  
Sex With Men

HIV pre-exposure prophylaxis (PrEP) effectively prevents HIV acquisition among men who have sex with men (MSM), but PrEP uptake has been associated with sexually transmitted infections (STIs). The effect of PrEP on STIs in MSM in the Deep South of the United States is unknown. We performed a retrospective analysis of adult MSM at an American Deep South PrEP clinic to calculate the prevalence and incidence rate of bacterial STIs (chlamydia, gonorrhea, and syphilis) and identify associated risk factors by linking incident STI to patient-reported outcomes; 139 MSM accessed the clinic between 2014 and 2018 with baseline bacterial STI prevalence of 11%. Twenty-six of 81 eligible MSM on PrEP had incident STIs with an incidence rate of 33.1 cases per 100 person-years. Significantly higher proportions of high PrEP adherence, multiple sexual partners, and inconsistent condom use were seen in those with incident STI, and we identified MSM with both high PrEP adherence and multiple sexual partners as being at especially high risk for bacterial STIs (hazard ratio: 7.57, 95% confidence interval: 1.75–32.74). Bacterial STIs are common after initiating PrEP in this clinic, and MSM reporting high PrEP adherence and multiple sexual partners have a significant risk for incident STI. High-risk sexual behaviors persisted after starting PrEP, highlighting the importance of ongoing, intensive sexual health screening and interventions.

Increases in HIV incidence among men who have sex with men undergoing repeat diagnostic HIV testing in Ontario, Canada

AIDS ◽  
2002 ◽  
Vol 16 (12) ◽  
pp. 1655-1661 ◽  
Author(s):  
Liviana Calzavara ◽  
Ann N. Burchell ◽  
Carol Major ◽  
Robert S. Remis ◽  
Paul Corey ◽  
...  
Keyword(s):  
Hiv Testing ◽  
Hiv Incidence ◽  
Sex With Men
Sign in / Sign up

Export Citation Format

Share Document