scholarly journals Compromise of renal transplant blood flow by an arteriovenous graft

2006 ◽  
Vol 21 (9) ◽  
pp. 2644-2646 ◽  
Author(s):  
Emily Symington ◽  
Behdad Afzali ◽  
Iain MacPhee ◽  
Eric S. Chemla
Keyword(s):  
Blood Flow ◽  
Renal Transplant ◽  
Arteriovenous Graft

scholarly journals Verapamil improves the outcome after cadaver renal transplantation.

1991 ◽  
Vol 2 (5) ◽  
pp. 983-990
Author(s):  
I Dawidson ◽  
P Rooth ◽  
C Lu ◽  
A Sagalowsky ◽  
K Diller ◽  
...  
Keyword(s):  
Blood Flow ◽  
Renal Transplantation ◽  
Renal Transplant ◽  
Oral Administration ◽  
Renal Artery ◽  
Graft Survival ◽  
Antilymphocyte Globulin ◽  
Acute Renal Dysfunction ◽  
Transplant Patients ◽  
Blood Flow Velocities

Because of their favorable effects on renal hemodynamics, calcium antagonists may have a major role in the prevention and management of certain types of acute renal dysfunction. In fact, verapamil (VP) was shown to prevent cyclosporin A (CsA)-induced decreases in RBF in mice and in cadaver renal transplant (CRT) recipients. The study presented here of 59 cadaver renal transplant patients evaluates the outcome from perioperative treatment with VP (N = 30) administered intraoperatively into the renal artery (10 mg) followed by oral administration of 120 mg every 8 to 12 h for 14 days versus no drug (N = 29). Early immunosuppression included azathioprine, corticosteroids, and antilymphocyte globulin with subsequent overlapping with CsA on days 5 and 6. Actuarial graft survival at 1 yr was different when the two groups were compared (P less than 0.05). Estimated graft survival at 1 yr for VP patients was 93.3 compared with 72.4% in control patients. The improved graft survival was most striking in repeat transplants with 90% graft survival at 1 yr for VP recipients versus 37.5% for controls. Compared with controls, VP recipients had significantly improved renal parenchymal diastolic blood flow velocities on the first day after surgery (7.8 versus 5.8 cm/s). By day 7, GFR were greater with VP (44 +/- 29 mL/min) versus controls (28 +/- 22 mL/min). Of VP patients, 67% (18 of 24) had GFR greater than 30 mL/min versus 33% (9 of 26) for control patients. Similarly, on the seventh day, 77% (21 of 30) of VP patients had serum creatinines less than 2.0 mg% versus 34% (10 of 29) for controls.(ABSTRACT TRUNCATED AT 250 WORDS)

Basic science and renal transplant

2019 ◽  
pp. 827-846
Author(s):  
John Reynard ◽  
Simon F Brewster ◽  
Suzanne Biers ◽  
Naomi Laura Neal
Keyword(s):  
Blood Flow ◽  
Renal Transplantation ◽  
Renal Replacement Therapy ◽  
Renal Transplant ◽  
Basic Science ◽  
Renal Physiology ◽  
Physiological Functions ◽  
Organ Rejection ◽  
Sodium And Potassium ◽  
Donor Transplant

This chapter covers the basic physiological functions of the kidney, bladder, and urethra. Renal anatomy is detailed, including the anatomical relations of the kidney. Renal physiology is covered in detail, including the regulation of renal blood flow and regulation of water, acid–base, sodium, and potassium balance. It includes the principles of renal replacement therapy and the principles of renal transplantation, including assessment of both the recipient and the donor. Transplant surgery is outlined, including commonly used drugs and complications and their management and common complications of renal transplant surgery. The different types of organ rejection are discussed, including their treatments.

Basic science and renal transplant

2013 ◽  
pp. 793-814
Author(s):  
John Reynard ◽  
Simon Brewster ◽  
Suzanne Biers
Keyword(s):  
Blood Flow ◽  
Renal Replacement Therapy ◽  
Renal Transplant ◽  
Water Balance ◽  
Basic Science ◽  
Renal Physiology ◽  
Potassium Excretion ◽  
Acid Base Balance ◽  
Base Balance ◽  
Sodium And Potassium

Basic physiology of bladder and urethra 794 Basic renal anatomy 796 Renal physiology: glomerular filtration and regulation of renal blood flow 800 Renal physiology: regulation of water balance 802 Renal physiology: regulation of sodium and potassium excretion 803 Renal physiology: acid–base balance 804 Renal replacement therapy ...

Assessment of Preservation Induced Reperfusion Injury via Intraoperative Renal Transplant Blood Flow and Endothelin Concentration Studies

1997 ◽  
pp. 714-718 ◽  
Author(s):  
Peter N. Jr Bretan ◽  
Errol Lobo ◽  
Johnny A. Chang ◽  
Ouvidiu Dumitrescu ◽  
Bulaklak Miller ◽  
...  
Keyword(s):  
Blood Flow ◽  
Renal Transplant ◽  
Reperfusion Injury

Novel treatment of a totally occluded venous outflow tract of an arteriovenous graft

2018 ◽  
Vol 20 (3) ◽  
pp. 333-336
Author(s):  
Crystal A Farrington ◽  
Ahmed K Abdel-Aal ◽  
Ammar Almehmi
Keyword(s):  
Blood Flow ◽  
Chronic Total Occlusion ◽  
Femoral Vein ◽  
Chronic Hemodialysis ◽  
Outflow Tract ◽  
Arteriovenous Graft ◽  
Initial Attempt ◽  
Venous Outflow ◽  
Total Occlusion ◽  
Vein Access

Introduction: Conventional guidewire techniques are not always sufficient to restore arteriovenous graft patency in patients with challenging vascular scenarios. We discuss a novel approach to the treatment of chronic total occlusion of the venous outflow tract to enable successful arteriovenous graft thrombectomy. Case presentation: A 28-year-old female with end-stage renal disease on chronic hemodialysis and recurrent arteriovenous graft thromboses presented with a clotted thigh graft. An existing ipsilateral common femoral vein stent was found to be chronically occluded, causing persistent venous outflow obstruction and rendering an initial attempt at thrombectomy unsuccessful due to wire buckling and the inability to navigate through the stent chronic total occlusion. Results: After establishing femoral vein access, a vibrational recanalization device was used to cross the occluded stent. The device was then removed, permitting routine angioplasty. Post-angioplasty angiogram revealed persistent intra-stent stenosis, so a covered stent was deployed with good angiographic results. Routine pharmaco-mechanical thrombectomy of the arteriovenous graft was then performed. Two additional stents were placed due to stenotic recoil in the venous limb of the graft. Angioplasty was also performed at the arteriovenous graft arterial anastomosis. Repeat imaging demonstrated marked improvement in the graft blood flow. Discussion: Total occlusion of the venous outflow tract prevents adequate blood flow through an arteriovenous graft and undermines successful thrombectomy. We describe the use of the Crosser vibrational recanalization device for the safe and effective treatment of a chronic total occlusion of the venous outflow tract, thus extending the life of the patient’s vascular access for hemodialysis.

scholarly journals RENAL TRANSPLANT BLOOD FLOW MEASUREMENT USING ULTRASONIC CONTRAST AGENTS

2001 ◽  
Vol 92 (6) ◽  
pp. 640-644
Author(s):  
Tsukasa Nishioka ◽  
Seiji Matsumoto ◽  
Eiji Konya ◽  
Takahiro Akiyama ◽  
Tskeshi Matsuura ◽  
...  
Keyword(s):  
Blood Flow ◽  
Renal Transplant ◽  
Contrast Agents ◽  
Flow Measurement ◽  
Blood Flow Measurement

Leukocyte and Platelet Depletion Improves Blood Flow and Function in a Renal Transplant Model

2012 ◽  
Vol 172 (1) ◽  
pp. 159-164 ◽  
Author(s):  
Phillip J. Yates ◽  
Sarah A. Hosgood ◽  
Michael L. Nicholson
Keyword(s):  
Blood Flow ◽  
Renal Transplant ◽  
And Function ◽  
Transplant Model ◽  
Platelet Depletion

Assessment of Preservation Induced Reperfusion Injury via Intraoperative Renal Transplant Blood Flow and Endothelin Concentration Studies

1997 ◽  
Vol 158 (3) ◽  
pp. 714-718 ◽  
Author(s):  
Peter N. Bretan ◽  
Errol Lobo ◽  
Johnny A. Chang ◽  
Ouvidiu Dumitrescu ◽  
Bulaklak Miller ◽  
...  
Keyword(s):  
Blood Flow ◽  
Renal Transplant ◽  
Reperfusion Injury
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