scholarly journals DNA base sequence effects on bulky lesion-induced conformational heterogeneity during DNA replication

2018 ◽  
Vol 46 (12) ◽  
pp. 6356-6370 ◽  
Author(s):  
Ang Cai ◽  
Katie A Wilson ◽  
Satyakam Patnaik ◽  
Stacey D Wetmore ◽  
Bongsup P Cho
1981 ◽  
Vol 152 (2) ◽  
pp. 183-208 ◽  
Author(s):  
G. Engler ◽  
A. Depicker ◽  
R. Maenhaut ◽  
R. Villarroel ◽  
M. Van Montagu ◽  
...  

1982 ◽  
Vol 15 (4) ◽  
pp. 343-351 ◽  
Author(s):  
Richard Lavery ◽  
Bernard Pullman ◽  
Krystyna Zakrzewska

1984 ◽  
Vol 4 (7) ◽  
pp. 1416-1419
Author(s):  
R B Lefebvre ◽  
S Riva ◽  
K I Berns

Deletion of an 11-base symmetrical sequence in the inverted terminal repetition of the adeno-associated virus 2 genome inhibits DNA replication. Substitution of either an 8- or a 12-base symmetrical sequence unrelated to the original 11-base sequence restores DNA replication.


2020 ◽  
pp. 133-157
Author(s):  
Alan McHughen

We now look at personal genetics and genomics, especially important with the rise of companies willing to analyze your own DNA (for a small fee, of course), giving you the raw genetic information about yourself and your ancestors. Although we previously learned that DNA is “the same” in all species, we now turn to the individual, you, and explore how your DNA base sequence differs from the DNA base sequence of a bacterium, a liverwort, a chimp, and your weird Uncle Jason. This chapter provides the background to appreciate the specific issues related to medical and health issues, and then genealogical studies, coming up in later chapters. For most people, personal genomics testing involves sending a sample of DNA, in the form of spit or a cheek swab, to a lab. What kind of analyses do the labs perform, and what information do they reveal? In addition to full DNA sequence tests, there’s a whole gamut of other DNA tests, including SNP tests, Y-chromosome tests, mtDNA tests, and more. Your DNA base sequence is a gold mine of information unique to you, and it is entirely yours to discover. Whether you are curious about your medical and health genetics, wish to connect with relatives and build a family tree, or are just fascinated at what information your ancestors provided you, these next chapters will help you dig up the hidden secrets of your own genetic heritage.


Sign in / Sign up

Export Citation Format

Share Document