scholarly journals Mouse Tumor Biology (MTB): a database of mouse models for human cancer

2014 ◽  
Vol 43 (D1) ◽  
pp. D818-D824 ◽  
Author(s):  
Carol J. Bult ◽  
Debra M. Krupke ◽  
Dale A. Begley ◽  
Joel E. Richardson ◽  
Steven B. Neuhauser ◽  
...  
Keyword(s):  
Mouse Models ◽  
Human Cancer ◽  
Tumor Biology ◽  
Mouse Tumor

scholarly journals Abstract 5102: Identifying relevant mouse models of human cancer using the mouse tumor biology database (MTB)

2018 ◽  
Author(s):  
Dale A. Begley ◽  
Debra M. Krupke ◽  
Steven B. Neuhauser ◽  
Joel E. Richardson ◽  
John P. Sundberg ◽  
...  
Keyword(s):  
Mouse Models ◽  
Human Cancer ◽  
Tumor Biology ◽  
Mouse Tumor

scholarly journals The Mouse Tumor Biology Database: A Comprehensive Resource for Mouse Models of Human Cancer

2017 ◽  
Vol 77 (21) ◽  
pp. e67-e70 ◽  
Author(s):  
Debra M. Krupke ◽  
Dale A. Begley ◽  
John P. Sundberg ◽  
Joel E. Richardson ◽  
Steven B. Neuhauser ◽  
...  
Keyword(s):  
Mouse Models ◽  
Human Cancer ◽  
Tumor Biology ◽  
Mouse Tumor

Abstract B50: Mouse Tumor Biology (MTB) database–An integrated data resource for GEM, inbred strains, and PDX models of human cancer

2018 ◽  
Author(s):  
Debra M. Krupke ◽  
Dale A. Begley ◽  
Steven B. Neuhauser ◽  
Joel E. Richardson ◽  
John P. Sundberg ◽  
...  
Keyword(s):  
Human Cancer ◽  
Tumor Biology ◽  
Inbred Strains ◽  
Mouse Tumor ◽  
Data Resource ◽  
Pdx Models

Abstract A05: The Mouse Tumor Biology (MTB) Database: An electronic tool for identifying and evaluating mouse and PDX models of human cancer

2014 ◽  
Author(s):  
Dale A. Begley ◽  
Debra M. Krupke ◽  
Steven B. Neuhauser ◽  
Joel E. Richardson ◽  
John P. Sundberg ◽  
...  
Keyword(s):  
Human Cancer ◽  
Tumor Biology ◽  
Mouse Tumor ◽  
Electronic Tool ◽  
Pdx Models

scholarly journals How Genetically Engineered Mouse Tumor Models Provide Insights Into Human Cancers

2011 ◽  
Vol 29 (16) ◽  
pp. 2273-2281 ◽  
Author(s):  
Katerina Politi ◽  
William Pao
Keyword(s):  
Mouse Models ◽  
Cancer Biology ◽  
Human Cancer ◽  
Genetically Engineered ◽  
Mouse Tumor ◽  
Tumor Models ◽  
Genetically Engineered Mouse Models ◽  
Human Cancers ◽  
Chemically Induced

Genetically engineered mouse models (GEMMs) of human cancer were first created nearly 30 years ago. These early transgenic models demonstrated that mouse cells could be transformed in vivo by expression of an oncogene. A new field emerged, dedicated to generating and using mouse models of human cancer to address a wide variety of questions in cancer biology. The aim of this review is to highlight the contributions of mouse models to the diagnosis and treatment of human cancers. Because of the breadth of the topic, we have selected representative examples of how GEMMs are clinically relevant rather than provided an exhaustive list of experiments. Today, as detailed here, sophisticated mouse models are being created to study many aspects of cancer biology, including but not limited to mechanisms of sensitivity and resistance to drug treatment, oncogene cooperation, early detection, and metastasis. Alternatives to GEMMs, such as chemically induced or spontaneous tumor models, are not discussed in this review.

scholarly journals Identifying mouse models for skin cancer using the Mouse Tumor Biology Database

2014 ◽  
Vol 23 (10) ◽  
pp. 761-763 ◽  
Author(s):  
Dale A. Begley ◽  
Debra M. Krupke ◽  
Steven B. Neuhauser ◽  
Joel E. Richardson ◽  
Paul N. Schofield ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Mouse Models ◽  
Tumor Biology ◽  
Mouse Tumor

Abstract 631: The mouse tumor biology database (MTB): An integrated data resource for mouse and patient derived xenograft (PDX) models of human cancer

2016 ◽  
Author(s):  
Dale A. Begley ◽  
Debbie M. Krupke ◽  
Steven B. Neuhauser ◽  
Joel E. Richardson ◽  
John P. Sundberg ◽  
...  
Keyword(s):  
Human Cancer ◽  
Tumor Biology ◽  
Mouse Tumor ◽  
Data Resource ◽  
Patient Derived Xenograft ◽  
Pdx Models

scholarly journals Finding mouse models of human lymphomas and leukemia's using the Jackson laboratory mouse tumor biology database

2015 ◽  
Vol 99 (3) ◽  
pp. 533-536 ◽  
Author(s):  
Dale A. Begley ◽  
John P. Sundberg ◽  
Debra M. Krupke ◽  
Steven B. Neuhauser ◽  
Carol J. Bult ◽  
...  
Keyword(s):  
Mouse Models ◽  
Laboratory Mouse ◽  
Tumor Biology ◽  
Mouse Tumor ◽  
Jackson Laboratory
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