scholarly journals The mycobacterial antibiotic resistance determinant WhiB7 acts as a transcriptional activator by binding the primary sigma factor SigA (RpoV)

2013 ◽  
Vol 41 (22) ◽  
pp. 10062-10076 ◽  
Author(s):  
Ján Burian ◽  
Grace Yim ◽  
Michael Hsing ◽  
Peter Axerio-Cilies ◽  
Artem Cherkasov ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Sigma Factor ◽  
Transcriptional Activator ◽  
Resistance Determinant ◽  
Antibiotic Resistance Determinant

scholarly journals Molecular Basis of NDM-1, a New Antibiotic Resistance Determinant

PLoS ONE ◽  
2011 ◽  
Vol 6 (8) ◽  
pp. e23606 ◽  
Author(s):  
Zhongjie Liang ◽  
Lianchun Li ◽  
Yuanyuan Wang ◽  
Limin Chen ◽  
Xiangqian Kong ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Molecular Basis ◽  
Resistance Determinant ◽  
Antibiotic Resistance Determinant

scholarly journals A multicopy suppressor screening approach as a means to identify antibiotic resistance determinant candidates in Yersinia pestis

2008 ◽  
Vol 8 (1) ◽  
pp. 122 ◽  
Author(s):  
Karen L Stirrett ◽  
Julian A Ferreras ◽  
Sebastian M Rossi ◽  
Richard L Moy ◽  
Fabio V Fonseca ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Yersinia Pestis ◽  
Resistance Determinant ◽  
Multicopy Suppressor ◽  
Screening Approach ◽  
Antibiotic Resistance Determinant

scholarly journals Further studies on the antibiotic resistance of Shigella sonnei: II. The acquisition of transferable antibiotic resistance in vivo

1968 ◽  
Vol 66 (3) ◽  
pp. 479-487 ◽  
Author(s):  
Joan R. Davies ◽  
W. N. Farrant ◽  
A. J. H. Tomlinson
Keyword(s):  
Drug Resistance ◽  
Antibiotic Resistance ◽  
Shigella Sonnei ◽  
Resistance Determinant ◽  
Resistance Transfer ◽  
Antibiotic Resistance Determinant

A method is described for the testing of strains of Sh. sonnei for antibiotic resistance, colicine type and drug resistance transfer using a multiple inoculator.The examination of 731 strains of Sh. sonnei isolated from convalescent cases and their family contacts showed that about 5% of individuals were excreting organisms which differed from the infecting strain by a single transferable antibiotic resistance determinant. It is suggested that the acquisition of such resistance may occur in 13% of family incidents.

scholarly journals Roles of rpoN, fliA,and flgR in Expression of Flagella inCampylobacter jejuni

2001 ◽  
Vol 183 (9) ◽  
pp. 2937-2942 ◽  
Author(s):  
Aparna Jagannathan ◽  
Chrystala Constantinidou ◽  
Charles W. Penn
Keyword(s):  
Campylobacter Jejuni ◽  
Genome Sequence ◽  
Sigma Factor ◽  
Transcriptional Activator ◽  
Alternative Sigma Factor ◽  
Wild Type ◽  
Electron Microscopic ◽  
Global Regulation ◽  
Mutant Strains ◽  
Microscopic Studies

ABSTRACT Three potential regulators of flagellar expression present in the genome sequence of Campylobacter jejuni NCTC 11168, the genes rpoN, flgR, andfliA, which encode the alternative sigma factor ς54, the ς54-associated transcriptional activator FlgR, and the flagellar sigma factor ς28, respectively, were investigated for their role in global regulation of flagellar expression. The three genes were insertionally inactivated inC. jejuni strains NCTC 11168 and NCTC 11828. Electron microscopic studies of the wild-type and mutant strains showed that therpoN and flgR mutants were nonflagellate and that the fliA mutant had truncated flagella. Immunoblotting experiments with the three mutants confirmed the roles of rpoN, flgR, and fliA in the expression of flagellin.

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