scholarly journals Quadruplex formation is necessary for stable PNA invasion into duplex DNA of BCL2 promoter region

2011 ◽  
Vol 39 (16) ◽  
pp. 7114-7123 ◽  
Author(s):  
M. I. Onyshchenko ◽  
T. I. Gaynutdinov ◽  
E. A. Englund ◽  
D. H. Appella ◽  
R. D. Neumann ◽  
...  
Keyword(s):  
Promoter Region ◽  
Duplex Dna ◽  
Quadruplex Formation

Preferential binding of anticancer drugs to triplex DNA compared to duplex DNA: a spectroscopic and calorimetric study

RSC Advances ◽  
2016 ◽  
Vol 6 (46) ◽  
pp. 39903-39917 ◽  
Author(s):  
Neelam Lohani ◽  
Moganty R. Rajeswari
Keyword(s):  
Anticancer Drugs ◽  
Promoter Region ◽  
Binding Study ◽  
Triplex Dna ◽  
Calorimetric Study ◽  
Duplex Dna ◽  
Calorimetric Technique ◽  
Preferential Binding

Binding study of adriamycin and actinomycin to triplex DNA formed on the promoter region of hmgb1 gene using spectroscopic and calorimetric technique.

968: Gelsolin Gene Silencing Involving Unusual Chromatin Structures and a Novel Stem Loop Structure of the Promoter Region in Human Bladder Cancer

2004 ◽  
Vol 171 (4S) ◽  
pp. 256-257
Author(s):  
Kazunori Haga ◽  
Ataru Sazawa ◽  
Toru Harabayashi ◽  
Nobuo Shinohara ◽  
Minoru Nomoto ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Gene Silencing ◽  
Promoter Region ◽  
Loop Structure ◽  
Human Bladder Cancer ◽  
Human Bladder ◽  
Stem Loop ◽  
Stem Loop Structure

Variation in the Promoter Region of the β Fibrinogen Gene Is Associated with Plasma Fibrinogen Levels in Smokers and Non-Smokers

1991 ◽  
Vol 65 (05) ◽  
pp. 487-490 ◽  
Author(s):  
A E Thomas ◽  
F R Green ◽  
C H Kelleher ◽  
H C Wilkes ◽  
P J Brennan ◽  
...  
Keyword(s):  
Heart Disease ◽  
Promoter Region ◽  
Fragment Length Polymorphism ◽  
Fibrinogen Level ◽  
Plasma Fibrinogen ◽  
Plasma Fibrinogen Level ◽  
Healthy Men ◽  
History Of ◽  
General Practices ◽  
Restriction Fragment Length

SummaryWe investigated the association between fibrinogen levels and a HaeIII restriction fragment length polymorphism located at −453 bp from the start of transcription of the β fibrinogen gene. 292 healthy men aged 45 to 69 years, recruited from general practices throughout Britain, were studied. None had a history of ischaemic heart disease. 41.1% (120) were smokers and fibrinogen levels were higher in this group. The frequency of the noncutting allele (designated H2) was 0.19 and was the same in smokers and non-smokers. The H2 allele was associated with elevated levels of fibrinogen in both smokers and non-smokers and the effect of genotype was similar in both groups. After smoking, HaeIII genotype was the strongest predictor of fibrinogen levels and explained 3.1% of the variance in fibrinogen levels. These results confirm earlier studies that variation at the fibrinogen locus contributes to the between-individual differences in plasma fibrinogen level.

Effect of Netropsin on One-electron Oxidation of Duplex DNA¶†

2004 ◽  
Vol 80 (3) ◽  
pp. 456 ◽  
Author(s):  
Lezah W. Roberts ◽  
Gary B. Schuster
Keyword(s):  
Duplex Dna
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