scholarly journals Design and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNA

2007 ◽  
Vol 35 (15) ◽  
pp. 5274-5274 ◽  
Author(s):  
N. Lin ◽  
J. Yan ◽  
Z. Huang ◽  
C. Altier ◽  
M. Li ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Design And Synthesis ◽  
Thymidine Triphosphate

scholarly journals Design and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNA

2007 ◽  
Vol 35 (4) ◽  
pp. 1222-1229 ◽  
Author(s):  
Na Lin ◽  
Jun Yan ◽  
Zhen Huang ◽  
Craig Altier ◽  
Minyong Li ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Design And Synthesis ◽  
Thymidine Triphosphate

ChemInform Abstract: Design and Synthesis of Bio-Isosteres of Thymidine Triphosphate.

ChemInform ◽  
2010 ◽  
Vol 29 (38) ◽  
pp. no-no
Author(s):  
A. O. GOLDRING ◽  
J. BALZARINI ◽  
I. H. GILBERT
Keyword(s):  
Design And Synthesis ◽  
Thymidine Triphosphate

Design and synthesis of boronic acid inhibitors of endothelial lipase

2012 ◽  
Vol 22 (3) ◽  
pp. 1397-1401 ◽  
Author(s):  
Daniel P. O’Connell ◽  
Daniel F. LeBlanc ◽  
Debra Cromley ◽  
Jeffrey Billheimer ◽  
Daniel J. Rader ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Endothelial Lipase ◽  
Design And Synthesis

Design and Synthesis of Long-Wavelength Fluorescent Boronic Acid Reporter Compounds

2007 ◽  
Vol 2007 (13) ◽  
pp. 2091-2099 ◽  
Author(s):  
Junfeng Wang ◽  
Shan Jin ◽  
Senol Akay ◽  
Binghe Wang
Keyword(s):  
Boronic Acid ◽  
Long Wavelength ◽  
Design And Synthesis

Design and synthesis of bio-isosteres of thymidine triphosphate

1998 ◽  
Vol 8 (10) ◽  
pp. 1211-1214 ◽  
Author(s):  
Alastair O. Goldring ◽  
Jan Balzarini ◽  
Ian H. Gilbert
Keyword(s):  
Design And Synthesis ◽  
Thymidine Triphosphate

scholarly journals The design and synthesis of high efficiency adsorption materials for 1,3-propanediol: physical and chemical structure regulation

RSC Advances ◽  
2020 ◽  
Vol 10 (62) ◽  
pp. 38085-38096
Author(s):  
Kexin Zheng ◽  
Long Jiang ◽  
Shitao Yu ◽  
Mo Xian ◽  
Zhanqian Song ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Chemical Structure ◽  
High Efficiency ◽  
Design And Synthesis ◽  
Chemically Modified ◽  
Specific Affinity ◽  
Structure Regulation ◽  
Physical And Chemical

Chemically modified materials efficiently captured 1,3-propanediol via the specific affinity between boronic acid and diol.

Prostatic Acid Phosphatase (PAP) Differentiated Ultracytochemically from Lysosomal Acid Phosphate in the Rat with a PAP/Specific Substrate, Phosphorylcholine

1975 ◽  
Vol 33 ◽  
pp. 450-451
Author(s):  
W. Allen Shannon ◽  
José A. Serrano ◽  
Hannah L. Wasserkrug ◽  
Anna A. Serrano ◽  
Arnold M. Seligman
Keyword(s):  
Acid Phosphatase ◽  
Phosphate Buffer ◽  
Prostatic Carcinoma ◽  
Prostatic Acid Phosphatase ◽  
Chemotherapeutic Agents ◽  
Specific Substrate ◽  
Acid Phosphate ◽  
Lysosomal Acid ◽  
Design And Synthesis ◽  
New Chemotherapeutic Agents

During the design and synthesis of new chemotherapeutic agents for prostatic carcinoma based on phosphorylated agents which might be enzyme-activated to cytotoxicity, phosphorylcholine, [(CH3)3+NCH2CH2OPO3Ca]Cl-, has been indicated to be a very specific substrate for prostatic acid phosphatase (PAP). This phenomenon has led to the development of specific histochemical and ultracytochemical methods for PAP using modifications of the Gomori lead method for acid phosphatase. Comparative histochemical results in prostate and kidney of the rat have been published earlier with phosphorylcholine (PC) and β-glycerophosphate (βGP). We now report the ultracytochemical results.Minced tissues were fixed in 3% glutaraldehyde-0.1 M phosphate buffered (pH 7.4) for 1.5 hr and rinsed overnight in several changes of 0.05 M phosphate buffer (pH 7.0) containing 7.5% sucrose. Tissues were incubated 30 min to 2 hr in Gomori acid phosphatase medium (2) containing 0.1 M substrate, either PC or βGP.

Tailoring microstructures of materials through biomimetics

1993 ◽  
Vol 51 ◽  
pp. 500-501
Author(s):  
Mehmet Sarikaya ◽  
Ilhan A. Aksay
Keyword(s):  
Chemical Properties ◽  
Design And Synthesis ◽  
Structure Sensitive ◽  
Macro Scale ◽  
Methods Of Synthesis ◽  
Successive Level ◽  
Engineering Materials ◽  
Physical And Chemical ◽  
And Chemical Properties ◽  
Synthesis Of Materials

Biomimetics involves investigation of structure, function, and methods of synthesis of biological composite materials. The goal is to apply this information to the design and synthesis of materials for engineering applications.Properties of engineering materials are structure sensitive through the whole spectrum of dimensions from nanometer to macro scale. The goal in designing and processing of technological materials, therefore, is to control microstructural evolution at each of these dimensions so as to achieve predictable physical and chemical properties. Control at each successive level of dimension, however, is a major challenge as is the retention of integrity between successive levels. Engineering materials are rarely fabricated to achieve more than a few of the desired properties and the synthesis techniques usually involve high temperature or low pressure conditions that are energy inefficient and environmentally damaging.In contrast to human-made materials, organisms synthesize composites whose intricate structures are more controlled at each scale and hierarchical order.

Design and synthesis of azaisoflavones

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
B Kang ◽  
YJ Jung ◽  
R Jeon
Keyword(s):  
Design And Synthesis

Computer Modeling-Assisted Design And Synthesis Of Flavonols Derivatives As Proteasome Inhibitors

Planta Medica ◽  
2016 ◽  
Vol 82 (05) ◽  
Author(s):  
KY Orabi ◽  
MS Abaza ◽  
KA ElSayed ◽  
AY Elnagar ◽  
SI Faggal ◽  
...  
Keyword(s):  
Computer Modeling ◽  
Proteasome Inhibitors ◽  
Design And Synthesis
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