Design and Synthesis of Long-Wavelength Fluorescent Boronic Acid Reporter Compounds

2007 ◽  
Vol 2007 (13) ◽  
pp. 2091-2099 ◽  
Author(s):  
Junfeng Wang ◽  
Shan Jin ◽  
Senol Akay ◽  
Binghe Wang
Keyword(s):  
Boronic Acid ◽  
Long Wavelength ◽  
Design And Synthesis

scholarly journals Design and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNA

2007 ◽  
Vol 35 (4) ◽  
pp. 1222-1229 ◽  
Author(s):  
Na Lin ◽  
Jun Yan ◽  
Zhen Huang ◽  
Craig Altier ◽  
Minyong Li ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Design And Synthesis ◽  
Thymidine Triphosphate

Design and synthesis of a squaraine dye for long wavelength fluorescence-based biosensors

2005 ◽  
Author(s):  
J. Bruce Pitner ◽  
K. Joseph Thomas ◽  
Douglas B. Sherman ◽  
Javier Alarcon ◽  
Ghulam Mohiuddin ◽  
...  
Keyword(s):  
Long Wavelength ◽  
Design And Synthesis ◽  
Squaraine Dye

scholarly journals A Long-Wavelength Fluorescent Squarylium Cyanine Dye Possessing Boronic Acid for Sensing Monosaccharides and Glycoproteins with High Enhancement in Aqueous Solution

Sensors ◽  
2012 ◽  
Vol 12 (5) ◽  
pp. 5420-5431 ◽  
Author(s):  
Shingo Saito ◽  
Tara L. Massie ◽  
Takeshi Maeda ◽  
Hiroyuki Nakazumi ◽  
Christa L. Colyer
Keyword(s):  
Aqueous Solution ◽  
Boronic Acid ◽  
Cyanine Dye ◽  
Long Wavelength

scholarly journals Design and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNA

2007 ◽  
Vol 35 (15) ◽  
pp. 5274-5274 ◽  
Author(s):  
N. Lin ◽  
J. Yan ◽  
Z. Huang ◽  
C. Altier ◽  
M. Li ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Design And Synthesis ◽  
Thymidine Triphosphate

Design and synthesis of boronic acid inhibitors of endothelial lipase

2012 ◽  
Vol 22 (3) ◽  
pp. 1397-1401 ◽  
Author(s):  
Daniel P. O’Connell ◽  
Daniel F. LeBlanc ◽  
Debra Cromley ◽  
Jeffrey Billheimer ◽  
Daniel J. Rader ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Endothelial Lipase ◽  
Design And Synthesis

A Long-Wavelength Fluorescent Probe for Saccharides Based on Boronic-Acid Receptor

2013 ◽  
Vol 31 (8) ◽  
pp. 1095-1101 ◽  
Author(s):  
Hongyan Bai ◽  
Qian Sun ◽  
Haiyu Tian ◽  
Junhong Qian ◽  
Lingyi Zhang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Boronic Acid ◽  
Acid Receptor ◽  
Long Wavelength

2-(4-Boronophenyl)quinoline-4-carboxylic acid derivatives: Design and synthesis, aggregation-induced emission characteristics, and binding activity studies for D-ribose with long-wavelength emission

2019 ◽  
Vol 44 (3-4) ◽  
pp. 152-160
Author(s):  
Guiqian Fang ◽  
Hao Wang ◽  
Zhancun Bian ◽  
Guimin Zhang ◽  
Min Guo ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Boronic Acid ◽  
Clinical Laboratory ◽  
Fluorescence Emission ◽  
Fluorescent Sensors ◽  
Intensity Change ◽  
Buffer Solution ◽  
Aggregation Induced Emission ◽  
Long Wavelength ◽  
Phenyl Boronic Acid

Long-wavelength fluorescent sensors with large Stokes shifts show useful applications in chemical biology and clinical laboratory diagnosis. We have recently reported [4-(4-{[3-(4-boronobenzamido)propyl]carbamoyl}quinolin-2-yl)phenyl]boronic acid that can selectively recognize d-ribose in a buffer solution of pH 7.4. However, the short emission wavelength (395 nm) and aggregation-caused quenching effect are not conducive to applications as a sensor. Novel diboronic acid compounds are synthesized using 2-(4-boronophenyl)quinoline-4-carboxylic acid as the building block and p-phenylenediamine as the linker. These compounds show aggregation-induced emission and fluorescence emission at about 500 nm. In addition, after binding to most carbohydrates, the aggregated state of the boronic acid–containing compounds is dissociated, resulting in fluorescence quenching. Using [4-(4-{[4-(3-borono-5-methoxybenzamido)phenyl]carbamoyl}quinoline-2-yl)phenyl]boronic acid as an example, addition of 55 mM of d-ribose resulted in the strongest quenching of 83% for all the tested carbohydrates, indicating selectively recognizing d-ribose. The reciprocal of the fluorescence intensity change showed a good linear relationship with the reciprocal of d-ribose concentration ( R2 ⩾ 0.99), indicating sensor binding to d-ribose in a ratio of 1:1 to form an inclusion complex. The fluorescence emission is red-shifted compared to 2-(4-boronophenyl)quinoline-4-carboxylic acid and its common derivatives, which provides a new method for the development of long-wavelength fluorescent sensors.

scholarly journals The design and synthesis of high efficiency adsorption materials for 1,3-propanediol: physical and chemical structure regulation

RSC Advances ◽  
2020 ◽  
Vol 10 (62) ◽  
pp. 38085-38096
Author(s):  
Kexin Zheng ◽  
Long Jiang ◽  
Shitao Yu ◽  
Mo Xian ◽  
Zhanqian Song ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Chemical Structure ◽  
High Efficiency ◽  
Design And Synthesis ◽  
Chemically Modified ◽  
Specific Affinity ◽  
Structure Regulation ◽  
Physical And Chemical

Chemically modified materials efficiently captured 1,3-propanediol via the specific affinity between boronic acid and diol.

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