scholarly journals Mouse Tumor Biology Database (MTB): status update and future directions

2007 ◽  
Vol 35 (Database) ◽  
pp. D638-D642 ◽  
Author(s):  
D. A. Begley ◽  
D. M. Krupke ◽  
M. J. Vincent ◽  
J. P. Sundberg ◽  
C. J. Bult ◽  
...  
Keyword(s):  
Tumor Biology ◽  
Mouse Tumor ◽  
Future Directions

scholarly journals Electronic access to mouse tumor data: the Mouse Tumor Biology Database (MTB) project

1999 ◽  
Vol 27 (1) ◽  
pp. 99-105 ◽  
Author(s):  
C. J. Bult ◽  
D. M. Krupke ◽  
J. T. Eppig
Keyword(s):  
Tumor Biology ◽  
Mouse Tumor ◽  
Electronic Access

scholarly journals Aggressive Colorectal Cancer in the Young

2020 ◽  
Vol 33 (05) ◽  
pp. 298-304
Author(s):  
Blake Read ◽  
Patricia Sylla
Keyword(s):  
Colorectal Cancer ◽  
Late Onset ◽  
Tumor Biology ◽  
Population Based ◽  
Average Risk ◽  
Future Directions ◽  
Screening Guidelines ◽  
Treatment And Prevention ◽  
Rising Incidence ◽  
Related Mortality

AbstractDespite the steady decline in the incidence of colorectal cancer (CRC) and cancer-related mortality in Americans of 50 years and older over the last few decades, there has been a disturbing trend of steadily rising incidence in early-onset colorectal cancer (EOCRC), defined as CRC in those younger than 50 years. With the incidence of EOCRC increasing from 4.8 per 100,000 in 1988 to 8.0 per 100,000 in 2015, and with the decreased rates in those older than 50 years largely attributed to improved screening in the older population, new screening recommendations have recently lowered the age for screening average-risk individuals from 50 to 45. EOCRC has been found to present differently from late-onset CRC, with a higher proportion of patients presenting with left-sided and rectal cancer, more aggressive histological features, and more advanced stage at the time of diagnosis. This article reviews the most recent evidence from population-based studies and institutional series, as well as the newest screening guidelines, and provides an up-to-date summary of our current understanding of EOCRC, from clinical presentation to tumor biology and prognosis, and future directions in treatment and prevention.

Abstract B50: Mouse Tumor Biology (MTB) database–An integrated data resource for GEM, inbred strains, and PDX models of human cancer

2018 ◽  
Author(s):  
Debra M. Krupke ◽  
Dale A. Begley ◽  
Steven B. Neuhauser ◽  
Joel E. Richardson ◽  
John P. Sundberg ◽  
...  
Keyword(s):  
Human Cancer ◽  
Tumor Biology ◽  
Inbred Strains ◽  
Mouse Tumor ◽  
Data Resource ◽  
Pdx Models

Abstract C18: Interpreting the cancer genome using the Mouse Tumor Biology (MTB) Database

2013 ◽  
Author(s):  
Debra M. Krupke ◽  
Dale A. Begley ◽  
Steven B. Neuhauser ◽  
Joel E. Richardson ◽  
John P. Sundberg ◽  
...  
Keyword(s):  
Tumor Biology ◽  
Cancer Genome ◽  
Mouse Tumor

Abstract A05: The Mouse Tumor Biology (MTB) Database: An electronic tool for identifying and evaluating mouse and PDX models of human cancer

2014 ◽  
Author(s):  
Dale A. Begley ◽  
Debra M. Krupke ◽  
Steven B. Neuhauser ◽  
Joel E. Richardson ◽  
John P. Sundberg ◽  
...  
Keyword(s):  
Human Cancer ◽  
Tumor Biology ◽  
Mouse Tumor ◽  
Electronic Tool ◽  
Pdx Models

scholarly journals The Mouse Tumor Biology Database (MTB)

2011 ◽  
Vol 49 (1) ◽  
pp. 218-223 ◽  
Author(s):  
D. A. Begley ◽  
D. M. Krupke ◽  
S. B. Neuhauser ◽  
J. E. Richardson ◽  
C. J. Bult ◽  
...  
Keyword(s):  
Tumor Biology ◽  
Mouse Tumor

scholarly journals Electronic access to data from mouse cancer models: The Mouse Tumor Biology database

10.1038/87160 ◽  
2001 ◽  
Vol 27 (S4) ◽  
pp. 65-66 ◽  
Author(s):  
Debra M. Krupke ◽  
Carol J. Bult ◽  
Dieter Naf ◽  
John P. Sundberg ◽  
Janan T. Eppig
Keyword(s):  
Tumor Biology ◽  
Mouse Tumor ◽  
Cancer Models ◽  
Electronic Access ◽  
Access To Data ◽  
Mouse Cancer Models

THE MOUSE TUMOR BIOLOGY DATABASE: INTEGRATED ACCESS TO MOUSE CANCER BIOLOGY DATA

2005 ◽  
Vol 31 (2) ◽  
pp. 259-270 ◽  
Author(s):  
Debra M. Krupke ◽  
Dieter Näf ◽  
Matthew J. Vincent ◽  
Theresa Allio ◽  
Igor Mikaelian ◽  
...  
Keyword(s):  
Cancer Biology ◽  
Tumor Biology ◽  
Mouse Tumor

scholarly journals Mouse Tumor Biology (MTB): a database of mouse models for human cancer

2014 ◽  
Vol 43 (D1) ◽  
pp. D818-D824 ◽  
Author(s):  
Carol J. Bult ◽  
Debra M. Krupke ◽  
Dale A. Begley ◽  
Joel E. Richardson ◽  
Steven B. Neuhauser ◽  
...  
Keyword(s):  
Mouse Models ◽  
Human Cancer ◽  
Tumor Biology ◽  
Mouse Tumor
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