scholarly journals Intron gain and loss in the evolution of the conserved eukaryotic recombination machinery

2002 ◽  
Vol 30 (23) ◽  
pp. 5175-5181 ◽  
Author(s):  
F. Hartung
Keyword(s):  
Intron Gain ◽  
Gain And Loss

scholarly journals Mechanisms of intron gain and loss in Cryptococcus

2008 ◽  
Vol 9 (1) ◽  
pp. R24 ◽  
Author(s):  
Thomas J Sharpton ◽  
Daniel E Neafsey ◽  
James E Galagan ◽  
John W Taylor
Keyword(s):  
Intron Gain ◽  
Gain And Loss

scholarly journals Multiple intron gain and loss events occurred during the evolution of Cenp-A gene

2013 ◽  
Vol 58 (18) ◽  
pp. 2174-2178 ◽  
Author(s):  
XinYu Fan ◽  
Li Yu ◽  
HuaiLiang Xu ◽  
Ying Li
Keyword(s):  
Intron Gain ◽  
Gain And Loss

scholarly journals The Role of Reverse Transcriptase in Intron Gain and Loss Mechanisms

2011 ◽  
Vol 29 (1) ◽  
pp. 179-186 ◽  
Author(s):  
Noa E. Cohen ◽  
Roy Shen ◽  
Liran Carmel
Keyword(s):  
Reverse Transcriptase ◽  
Intron Gain ◽  
Gain And Loss ◽  
Loss Mechanisms

scholarly journals Mechanisms of intron gain and loss in Drosophila

2011 ◽  
Vol 11 (1) ◽  
pp. 364 ◽  
Author(s):  
Paul Yenerall ◽  
Bradlee Krupa ◽  
Leming Zhou
Keyword(s):  
Intron Gain ◽  
Gain And Loss

The biology of intron gain and loss

2006 ◽  
Vol 22 (1) ◽  
pp. 16-22 ◽  
Author(s):  
Daniel C. Jeffares ◽  
Tobias Mourier ◽  
David Penny
Keyword(s):  
Intron Gain ◽  
Gain And Loss

scholarly journals Spliceosomal intronogenesis

2016 ◽  
Vol 113 (23) ◽  
pp. 6514-6519 ◽  
Author(s):  
Sujin Lee ◽  
Scott W. Stevens
Keyword(s):  
Phylogenetic Analyses ◽  
Intron Loss ◽  
Intron Gain ◽  
The Novel ◽  
Intervening Sequences ◽  
Gain And Loss ◽  
Nuclear Genomes ◽  
Yeast Genes ◽  
Novel Allele

The presence of intervening sequences, termed introns, is a defining characteristic of eukaryotic nuclear genomes. Once transcribed into pre-mRNA, these introns must be removed within the spliceosome before export of the processed mRNA to the cytoplasm, where it is translated into protein. Although intron loss has been demonstrated experimentally, several mysteries remain regarding the origin and propagation of introns. Indeed, documented evidence of gain of an intron has only been suggested by phylogenetic analyses. We report the use of a strategy that detects selected intron gain and loss events. We have experimentally verified, to our knowledge, the first demonstrations of intron transposition in any organism. From our screen, we detected two separate intron gain events characterized by the perfect transposition of a reporter intron into the yeast genes RPL8B and ADH2, respectively. We show that the newly acquired introns are able to be removed from their respective pre-mRNAs by the spliceosome. Additionally, the novel allele, RPL8Bint, is functional when overexpressed within the genome in a strain lacking the Rpl8 paralogue RPL8A, demonstrating that the gene targeted for intronogenesis is functional.

scholarly journals High Rate of Recent Intron Gain and Loss in Simultaneously Duplicated Arabidopsis Genes

2006 ◽  
Vol 23 (8) ◽  
pp. 1548-1557 ◽  
Author(s):  
David G. Knowles ◽  
Aoife McLysaght
Keyword(s):  
Intron Gain ◽  
High Rate ◽  
Gain And Loss

scholarly journals Patterns of Intron Gain and Loss in Fungi

PLoS Biology ◽  
2004 ◽  
Vol 2 (12) ◽  
pp. e422 ◽  
Author(s):  
Cydney B Nielsen ◽  
Brad Friedman ◽  
Bruce Birren ◽  
Christopher B Burge ◽  
James E Galagan
Keyword(s):  
Intron Gain ◽  
Gain And Loss
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