scholarly journals Model studies of interactions between nucleic acids and proteins: hydrogen bonding of amides with nucleic acid bases

1979 ◽  
Vol 6 (3) ◽  
pp. 1063-1072 ◽  
Author(s):  
Gérard Lancelot ◽  
Hélène Claude
Keyword(s):  
Hydrogen Bonding ◽  
Nucleic Acid ◽  
Nucleic Acids ◽  
Nucleic Acid Bases ◽  
Model Studies

Binding of metal ions and water molecules to nucleic acid bases: the influence of water molecule coordination to a metal ion on water–nucleic acid base hydrogen bonds

2019 ◽  
Vol 75 (3) ◽  
pp. 301-309
Author(s):  
Jelena M. Andrić ◽  
Ivana M. Stanković ◽  
Snežana D. Zarić
Keyword(s):  
Nucleic Acid ◽  
Hydrogen Bonds ◽  
Nucleic Acids ◽  
Metal Ions ◽  
Quantum Chemical Calculations ◽  
Quantum Chemical ◽  
Metal Ion ◽  
Water Molecules ◽  
Nucleic Acid Bases ◽  
Coordinated Water

The interactions of nucleic acid bases with non-coordinated and coordinated water molecules were studied by analyzing data in the Protein Data Bank (PDB) and by quantum chemical calculations. The analysis of the data in the crystal structures from the PDB indicates that hydrogen bonds involving oxygen or nitrogen atoms of nucleic acid bases and water molecules are shorter when water is bonded to a metal ion. These results are in agreement with the quantum chemical calculations on geometries and interaction energies of hydrogen bonds; the calculations on model systems show that hydrogen bonds of nucleic acid bases with water bonded to a metal ion are stronger than hydrogen bonds with non-coordinated water. These calculated values are similar to the strength of hydrogen bonds between nucleic acid bases. The results presented in this paper may be relevant to understand the role of water molecules and metal ions in the process of replication and stabilization of nucleic acids and also to understand the possible toxicity of metal ion interactions with nucleic acids.

scholarly journals Chemical structure of QAII, one of the covalently bound adducts of carcinogenic 4-nitroquinoline 1-oxide with nucleic acid bases of cellular nucleic acids.

1975 ◽  
Vol 23 (11) ◽  
pp. 3041-3043 ◽  
Author(s):  
YUTAKA KAWAZOE ◽  
MISAKO ARAKI ◽  
GUANGFU HUANG ◽  
TOSHIHIKO OKAMOTO ◽  
MITSUHIKO TADA ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Chemical Structure ◽  
Nucleic Acid Bases ◽  
Covalently Bound

scholarly journals Recognition of Nucleic Acid Bases and Base-pairs by Hydrogen Bonding to Amino Acid Side-chains

2003 ◽  
Vol 327 (4) ◽  
pp. 781-796 ◽  
Author(s):  
Alan C. Cheng ◽  
William W. Chen ◽  
Cynthia N. Fuhrmann ◽  
Alan D. Frankel
Keyword(s):  
Hydrogen Bonding ◽  
Amino Acid ◽  
Nucleic Acid ◽  
Side Chains ◽  
Nucleic Acid Bases ◽  
Base Pairs ◽  
Amino Acid Side Chains

scholarly journals Site Preferences of Nucleic Acid Bases Hydrogen Bonding to Glycine Dipeptide

2015 ◽  
Vol 73 (4) ◽  
pp. 357
Author(s):  
Chang Liu ◽  
Ge Yu ◽  
Cuiying Huang ◽  
Changsheng Wang
Keyword(s):  
Hydrogen Bonding ◽  
Nucleic Acid ◽  
Nucleic Acid Bases ◽  
Site Preferences
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